{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:26:07Z","timestamp":1786980367999,"version":"build-2736575974"},"reference-count":0,"publisher":"American Diabetes Association","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.diabetesjournals.org\/journals\/pages\/license"}],"content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Many adults with type 1 diabetes (T1D) have overweight or obesity, underscoring the need for effective dietary weight loss strategies in this population. Time-restricted eating (TRE) has emerged as a popular approach for weight loss; however, its efficacy and safety in T1D have not been evaluated. We examined whether TRE is more effective for reducing body weight than standard care (daily calorie restriction [CR]), or compared with a control group, in adults with T1D and overweight or obesity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                    <jats:p>Participants were randomized to one of three groups for 6 months: 8-h TRE (eating only between 12:00 p.m. and 8:00 p.m., without calorie counting) versus CR (25% energy restriction daily), and compared with a no-intervention control group. The primary outcome was percent change in body weight by month 6.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Thirty-two participants were randomized. By month 6, body weight did not change significantly in the TRE group (\u22122.19% [95% CI \u22125.70, \u22121.31]) or CR group (\u22120.47% [95% CI \u22124.72, 3.78]) relative to a control group, or between TRE and CR groups (\u22121.73% [95% CI \u22125.37, 1.92]). HbA1c levels were significantly reduced by the TRE group when compared with the CR group (\u22120.46% [95% CI \u22120.80, \u22120.12]). There were no significant differences in total insulin dose or mean glucose levels across groups. TRE did not increase the risk for diabetic ketoacidosis, severe hypoglycemia, or severe hyperglycemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>These findings suggest that TRE may be a safe approach for reducing HbA1c levels in T1D, although not more effective for weight loss compared with CR or a control group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2337\/dc26-1093","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:38:18Z","timestamp":1786977498000},"update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy and Safety of Time-Restricted Eating in Adults With Type 1 Diabetes: A Randomized Controlled Trial"],"prefix":"10.2337","author":[{"given":"Mary-Claire","family":"Runchey","sequence":"first","affiliation":[{"name":"1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Corapi","sequence":"additional","affiliation":[{"name":"1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasiliki","family":"Pavlou","sequence":"additional","affiliation":[{"name":"1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Cienfuegos","sequence":"additional","affiliation":[{"name":"1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhao","family":"Lin","sequence":"additional","affiliation":[{"name":"1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Ezpeleta","sequence":"additional","affiliation":[{"name":"1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelsey","family":"Gabel","sequence":"additional","affiliation":[{"name":"1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Tussing-Humphreys","sequence":"additional","affiliation":[{"name":"1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL"},{"name":"2University of Illinois Cancer Center, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa M.","family":"Oddo","sequence":"additional","affiliation":[{"name":"1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaina J.","family":"Alexandria","sequence":"additional","affiliation":[{"name":"3Biostatistics & Informatics, Department of Preventive Medicine, Northwestern University, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julienne","family":"Sanchez","sequence":"additional","affiliation":[{"name":"4College of Medicine, Division of Endocrinology, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry","family":"Unterman","sequence":"additional","affiliation":[{"name":"4College of Medicine, Division of Endocrinology, University of Illinois Chicago, Chicago, IL"},{"name":"5Endocrinology, Jesse Brown VA Medical Center, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6210-2307","authenticated-orcid":false,"given":"Lisa S.","family":"Chow","sequence":"additional","affiliation":[{"name":"6Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, University of Minnesota, Minneapolis, MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3790-6255","authenticated-orcid":false,"given":"Alaina P.","family":"Vidmar","sequence":"additional","affiliation":[{"name":"7Center for Endocrinology, Diabetes and Metabolism, Department of Pediatrics, Children's Hospital Los Angeles and Keck School of Medicine of the University of Southern California, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0686-1069","authenticated-orcid":false,"given":"Sirimon","family":"Reutrakul","sequence":"additional","affiliation":[{"name":"4College of Medicine, Division of Endocrinology, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krista A.","family":"Varady","sequence":"additional","affiliation":[{"name":"1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL"},{"name":"2University of Illinois Cancer Center, University of Illinois Chicago, Chicago, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","published-online":{"date-parts":[[2026,8,17]]},"container-title":["Diabetes Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/doi\/10.2337\/dc26-1093\/893558\/dc261093.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/doi\/10.2337\/dc26-1093\/893558\/dc261093.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:38:18Z","timestamp":1786977498000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/care\/article\/doi\/10.2337\/dc26-1093\/172390\/Efficacy-and-Safety-of-Time-Restricted-Eating-in"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,17]]},"references-count":0,"URL":"https:\/\/doi.org\/10.2337\/dc26-1093","relation":{},"ISSN":["0149-5992","1935-5548"],"issn-type":[{"value":"0149-5992","type":"print"},{"value":"1935-5548","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,17]]},"article-number":"dc261093"}}