{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T07:33:30Z","timestamp":1778657610174,"version":"3.51.4"},"reference-count":0,"publisher":"American Diabetes Association","issue":"9","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1969,9,1]]},"abstract":"<jats:p>Plasma glucose, NEFA, insulin and blood pyruvate levels before and after oral\/intravenous glucose administration have been compared in a group of twenty-eight thyrotoxic subjects and a group of control subjects matched for age, sex and degree of obesity.<\/jats:p>\n               <jats:p>The mean fasting plasma glucose level was elevated, and 44 per cent of oral and 24 per cent of intravenous glucose tolerance tests were impaired in the thyrotoxic group.<\/jats:p>\n               <jats:p>The mean plasma insulin level in the thyrotoxic group was elevated both before and after oral and intravenous glucose administration.<\/jats:p>\n               <jats:p>Mean fasting plasma NEFA levels were elevated in the thyrotoxic group but fell to normal levels following glucose administration.<\/jats:p>\n               <jats:p>Mean fasting blood pyruvate levels were similar in control and thyrotoxic groups but abnormally elevated levels were observed in the latter following oral glucose administration.<\/jats:p>\n               <jats:p>Mean fasting serum triglyceride levels were similar in both groups, but the mean fasting serum cholesterol was significantly lower in the thyrotoxic subjects.<\/jats:p>\n               <jats:p>The possible significance of these abnormalities is discussed.<\/jats:p>","DOI":"10.2337\/diab.18.9.633","type":"journal-article","created":{"date-parts":[[2014,12,11]],"date-time":"2014-12-11T05:37:01Z","timestamp":1418276221000},"page":"633-639","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":70,"title":["Effects of Oral and Intravenous Glucose Loading in Thyrotoxicosis: Studies of Plasma Glucose, Free Fatty Acid, Plasma Insulin and Blood Pyruvate Levels"],"prefix":"10.2337","volume":"18","author":[{"given":"J W H","family":"Doar","sequence":"first","affiliation":[{"name":"The Alexander Simpson Laboratory for Metabolic Research, St. Mary's Hospital Medical School, and the University of London\u2008London, W2, England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T C B","family":"Stamp","sequence":"additional","affiliation":[{"name":"The Alexander Simpson Laboratory for Metabolic Research, St. Mary's Hospital Medical School, and the University of London\u2008London, W2, England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Wynn","sequence":"additional","affiliation":[{"name":"The Alexander Simpson Laboratory for Metabolic Research, St. Mary's Hospital Medical School, and the University of London\u2008London, W2, England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F C","family":"Path","sequence":"additional","affiliation":[{"name":"The Alexander Simpson Laboratory for Metabolic Research, St. Mary's Hospital Medical School, and the University of London\u2008London, W2, England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T K","family":"Audhya","sequence":"additional","affiliation":[{"name":"The Alexander Simpson Laboratory for Metabolic Research, St. Mary's Hospital Medical School, and the University of London\u2008London, W2, England"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","container-title":["Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.org\/diabetes\/diabetes\/article-pdf\/18\/9\/633\/344941\/18-9-633.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article-pdf\/18\/9\/633\/344941\/18-9-633.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T16:16:12Z","timestamp":1667405772000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article\/18\/9\/633\/3122\/Effects-of-Oral-and-Intravenous-Glucose-Loading-in"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,9,1]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1969,9,1]]}},"URL":"https:\/\/doi.org\/10.2337\/diab.18.9.633","relation":{},"ISSN":["0012-1797","1939-327X"],"issn-type":[{"value":"0012-1797","type":"print"},{"value":"1939-327X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,9,1]]}}}