{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T09:19:33Z","timestamp":1759483173940},"reference-count":0,"publisher":"American Diabetes Association","issue":"7","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1980,7,1]]},"abstract":"<jats:p>The effect of diabetes on myocardial collagen metabolism was investigated in rats. Diabetes was induced by an i.v. injection of streptozotocin (60 mg\/kg). The animals were killed after 3, 6, 18, or 26 wk of diabetes. Urinary glucose levels were measured by Tes-Tape. The myocardium was quickly removed and homogenized. Collagen was estimated by hydroxyproline content. Collagen synthesis was measured by 14C-proline incorporation. Myocardial collagen concentration and collagen synthesis was not altered in the diabetic rats. Collagen concentration did appear to increase in the 18- and 26-wk rats, but this was probably an age-related phenomenon. These results suggest that diabetes does not alter collagen metabolism in rats.<\/jats:p>","DOI":"10.2337\/diab.29.7.547","type":"journal-article","created":{"date-parts":[[2013,9,19]],"date-time":"2013-09-19T17:16:02Z","timestamp":1379610962000},"page":"547-550","update-policy":"http:\/\/dx.doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":14,"title":["Collagen Metabolism in the Myocardium from Streptozotocin-diabetic Rats"],"prefix":"10.2337","volume":"29","author":[{"given":"John","family":"Modrak","sequence":"first","affiliation":[{"name":"Department of Pharmacodynamics and Toxicology, College of Pharmacy, University of Nebraska Medical Center\u2008Omaha, Nebraska"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","container-title":["Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.org\/diabetes\/diabetes\/article-pdf\/29\/7\/547\/350965\/29-7-547.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article-pdf\/29\/7\/547\/350965\/29-7-547.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T16:34:07Z","timestamp":1667406847000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article\/29\/7\/547\/4862\/Collagen-Metabolism-in-the-Myocardium-from"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,7,1]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1980,7,1]]}},"URL":"https:\/\/doi.org\/10.2337\/diab.29.7.547","relation":{},"ISSN":["0012-1797","1939-327X"],"issn-type":[{"value":"0012-1797","type":"print"},{"value":"1939-327X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,7,1]]}}}