{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:25:44Z","timestamp":1791563144077,"version":"4.3.4"},"reference-count":0,"publisher":"American Diabetes Association","issue":"Supplement_2","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1983,6,1]]},"abstract":"<jats:p>Our longitudinal study of urinary albumin excretion rate in long-term insulin-dependent diabetics without proteinuria (negative albustix) suggests that early detection of patients at high and low risk of developing persistent proteinuria, i.e., diabetic nephropathy, is possible by using a sensitive method for albumin determination.<\/jats:p>\n               <jats:p>Our prospective studies in young insulin-dependent diabetics with diabetic nephropathy show that the rate of decline in giomerular filtration rate (GFR) varies considerably, with a mean of 0.75 ml\/min\/mo and a range from 0.1 to 1.50 ml\/min\/mo, and that an increase in arterial blood pressure to a hypertensive level is an early feature; 43% of the patients had diastolic blood pressure &amp;gt;100 mm Hg. Early and aggressive antihypertensive treatment reduces both albuminuria and the rate of decline in GFR in young patients with diabetic nephropathy.<\/jats:p>","DOI":"10.2337\/diab.32.2.s83","type":"journal-article","created":{"date-parts":[[2013,9,19]],"date-time":"2013-09-19T17:16:02Z","timestamp":1379610962000},"page":"83-87","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":64,"title":["Diabetic Nephropathy and Arterial Hypertension: The Effect of Antihypertensive Treatment"],"prefix":"10.2337","volume":"32","author":[{"given":"Hans-Henrik","family":"Parving","sequence":"first","affiliation":[{"name":"Steno Memorial Hospital, Geniofte, the Department of Clinical Physiology, Bispebjerg Hospital, and the Department of Medicine F. Herlev Hospital\u2008Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan R","family":"Andersen","sequence":"additional","affiliation":[{"name":"Steno Memorial Hospital, Geniofte, the Department of Clinical Physiology, Bispebjerg Hospital, and the Department of Medicine F. Herlev Hospital\u2008Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulla M","family":"Smidt","sequence":"additional","affiliation":[{"name":"Steno Memorial Hospital, Geniofte, the Department of Clinical Physiology, Bispebjerg Hospital, and the Department of Medicine F. Herlev Hospital\u2008Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens Sandahl","family":"Christiansen","sequence":"additional","affiliation":[{"name":"Steno Memorial Hospital, Geniofte, the Department of Clinical Physiology, Bispebjerg Hospital, and the Department of Medicine F. Herlev Hospital\u2008Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgitte","family":"Oxenb\u00f8ll","sequence":"additional","affiliation":[{"name":"Steno Memorial Hospital, Geniofte, the Department of Clinical Physiology, Bispebjerg Hospital, and the Department of Medicine F. Herlev Hospital\u2008Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per Aa","family":"Svendsen","sequence":"additional","affiliation":[{"name":"Steno Memorial Hospital, Geniofte, the Department of Clinical Physiology, Bispebjerg Hospital, and the Department of Medicine F. Herlev Hospital\u2008Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","container-title":["Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.org\/diabetes\/diabetes\/article-pdf\/32\/Supplement_2\/83\/506463\/32-2-s83.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article-pdf\/32\/Supplement_2\/83\/506463\/32-2-s83.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T16:39:49Z","timestamp":1667407189000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article\/32\/Supplement_2\/83\/7022\/Diabetic-Nephropathy-and-Arterial-Hypertension-The"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,6,1]]},"references-count":0,"journal-issue":{"issue":"Supplement_2","published-print":{"date-parts":[[1983,6,1]]}},"URL":"https:\/\/doi.org\/10.2337\/diab.32.2.s83","relation":{},"ISSN":["0012-1797","1939-327X"],"issn-type":[{"value":"0012-1797","type":"print"},{"value":"1939-327X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,6,1]]}}}