{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T04:29:38Z","timestamp":1667449778677},"reference-count":0,"publisher":"American Diabetes Association","issue":"Supplement_1","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1989,1,1]]},"abstract":"<jats:p>Eight dogs with previously established kidney allografts, immunosuppressed with cyclosporin A, received islet allografts from their respective original kidney donors. The median islet-graft functional survival was only 10.5 days, significantly less than for six similarly immunosuppressed dogs receiving only islet allografts (48.5 days, P &amp;lt; .05). Three of the eight dogs that received sequential kidney and islet allografts had experienced no kidney-graft rejection episodes before islet transplantation, but their islet grafts were all rejected within 19 days. In the pancreatectomized dog, prior donor-specific kidney transplantation has an adverse effect on subsequent islet-graft survival.<\/jats:p>","DOI":"10.2337\/diab.38.1.s179","type":"journal-article","created":{"date-parts":[[2013,9,19]],"date-time":"2013-09-19T17:16:02Z","timestamp":1379610962000},"page":"179-181","update-policy":"http:\/\/dx.doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":1,"title":["Failure of Canine Islet Allotransplantation After Kidney Transplantation"],"prefix":"10.2337","volume":"38","author":[{"given":"Andrew J","family":"Guy","sequence":"first","affiliation":[{"name":"Department of Surgery, The Medical School\u2008Newcastle upon Tyne, England, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S Michael","family":"Griffin","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Medical School\u2008Newcastle upon Tyne, England, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek","family":"Alderson","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Medical School\u2008Newcastle upon Tyne, England, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R","family":"Farndon","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Medical School\u2008Newcastle upon Tyne, England, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","container-title":["Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.org\/diabetes\/diabetes\/article-pdf\/38\/Supplement_1\/179\/513948\/38-1-s179.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article-pdf\/38\/Supplement_1\/179\/513948\/38-1-s179.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T16:10:36Z","timestamp":1667405436000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article\/38\/Supplement_1\/179\/15013\/Failure-of-Canine-Islet-Allotransplantation-After"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,1,1]]},"references-count":0,"journal-issue":{"issue":"Supplement_1","published-print":{"date-parts":[[1989,1,1]]}},"URL":"https:\/\/doi.org\/10.2337\/diab.38.1.s179","relation":{},"ISSN":["0012-1797","1939-327X"],"issn-type":[{"value":"0012-1797","type":"print"},{"value":"1939-327X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,1,1]]}}}