{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T04:30:16Z","timestamp":1667449816857},"reference-count":0,"publisher":"American Diabetes Association","issue":"Supplement_2","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1991,12,1]]},"abstract":"<jats:p>A 75-g oral glucose tolerance test (OGTT) was performed in 615 nonobese pregnant women (mean \u00b1 SD age 29.7 \u00b1 4.3 yr) who were referred to the Division of Internal Medicine at our diabetes center because of glycosuria. Seventy-seven cases were found to have urinary glucose at the first trimester, 185 at the second trimester, and 353 at the third trimester. With their 75-g OGTT results, the diagnostic criteria of borderline (formulated by the Japan Diabetes Society), impaired glucose tolerance (IGT; defined by the World Health Organization [WHO]), and gestational diabetes mellitus (GDM; determined by the Japan Society of Obstetrics &amp; Gynecology standards) were compared through blood glucose (BG) curves and immunoreactive insulin (IRI) responses. Borderline (fasting BG \u22656.1 and &amp;lt;7.8 mM and 2-h BG \u22656.7 and &amp;lt;11.1 mM) is neither diabetes nor normal. IGT is as referred to by the WHO. GDM exceeds two points of fasting BG \u22655.6 mM, 1-h BG \u226510.0 mM, or 2-h BG \u22658.3 mM. Diabetes mellitus (DM) is as referred to by the Japan Diabetes Society (same as the WHO). The prevalence of abnormal glucose tolerance among all 615 pregnant women was 54.6% in borderline, 24.5% in IGT, 7.3% in GDM, and 3.4% in DM. The 2-h BG levels in IGT during the first trimester were higher than in borderline (P&amp;lt; 0.01). The 1- and 2-h levels in GDM without DM in a given trimester were higher than in borderline (P&amp;lt; 0.001\u20130.05). However, there were low responses of IRI at the early phase in each group. The prevalence of low responders whose 30-min \u0394IRI (pM)\/\u0394BG (mM) was &amp;lt; 54 was 47% in borderline, 52% in IGT, 83% in GDM, and 100% in DM at the first trimester. Moreover, among 7 cases who were low-IRI responders during their first pregnancy, 3 developed GDM or DM during their second pregnancy. Although it is difficult to clarify which criteria for GDM are better, these data indicate that a low 30-min \u0394IRI\/\u0394BG on 75-g OGTT is an important piece of evidence predicting the future onset of non-insulin-dependent DM.<\/jats:p>","DOI":"10.2337\/diab.40.2.s30","type":"journal-article","created":{"date-parts":[[2013,9,19]],"date-time":"2013-09-19T17:22:06Z","timestamp":1379611326000},"page":"30-34","update-policy":"http:\/\/dx.doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of Diagnostic Criteria of IGT, Borderline, and GDM: Blood Glucose Curve and IRI Response"],"prefix":"10.2337","volume":"40","author":[{"given":"Yasue","family":"Omori","sequence":"first","affiliation":[{"name":"Diabetes Center, Tokyo Women's Medical College\u2008Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satomi","family":"Minei","sequence":"additional","affiliation":[{"name":"Diabetes Center, Tokyo Women's Medical College\u2008Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuko","family":"Uchigata","sequence":"additional","affiliation":[{"name":"Diabetes Center, Tokyo Women's Medical College\u2008Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meimi","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Diabetes Center, Tokyo Women's Medical College\u2008Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Sanaka","sequence":"additional","affiliation":[{"name":"Diabetes Center, Tokyo Women's Medical College\u2008Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masashi","family":"Honda","sequence":"additional","affiliation":[{"name":"Diabetes Center, Tokyo Women's Medical College\u2008Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukimasa","family":"Hirata","sequence":"additional","affiliation":[{"name":"Diabetes Center, Tokyo Women's Medical College\u2008Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","container-title":["Diabetes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.org\/diabetes\/diabetes\/article-pdf\/40\/Supplement_2\/30\/355552\/40-2-s30.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article-pdf\/40\/Supplement_2\/30\/355552\/40-2-s30.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T16:18:06Z","timestamp":1667405886000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/diabetes\/article\/40\/Supplement_2\/30\/9055\/Comparison-of-Diagnostic-Criteria-of-IGT"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,12,1]]},"references-count":0,"journal-issue":{"issue":"Supplement_2","published-print":{"date-parts":[[1991,12,1]]}},"URL":"https:\/\/doi.org\/10.2337\/diab.40.2.s30","relation":{},"ISSN":["0012-1797","1939-327X"],"issn-type":[{"value":"0012-1797","type":"print"},{"value":"1939-327X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,12,1]]}}}