{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T05:55:44Z","timestamp":1697349344133},"reference-count":0,"publisher":"American Diabetes Association","issue":"1","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1978,1,1]]},"abstract":"<jats:p>References and texts in the fields of diabetes and clinical chemistry commonly report that ascorbic acid when given orally or parenterally gives a false-positive reaction to the copper reduction glucose test (Clinitest). This impression is based on a study in which ascorbic acid (250 mg.\/dl.) was added to urine in vitro, with a resultant positive-test reading in the absence of glucose. Ascorbic acid is a reducing agent, and theoretically it could interfere with the copper reduction method of glucose detection. In the current study 10 nondiabetic men were ingesting 4 and 6 gm. ascorbic acid per day. A total of 360 glucose detection tests with the copper reduction method were undertaken. In no instance was there a positive reaction to the glucose test.<\/jats:p>","DOI":"10.2337\/diacare.1.1.34","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T22:51:27Z","timestamp":1173135087000},"page":"34-35","update-policy":"http:\/\/dx.doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":3,"title":["Noneffect of Oral Urinary Copper Ascorbic Acid on Reduction Glucose Test"],"prefix":"10.2337","volume":"1","author":[{"given":"Milap C","family":"Nahata","sequence":"first","affiliation":[{"name":"College of Pharmacy, Ohio State University, Columbus, and State University of New York\u2008Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don C","family":"McLeod","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Ohio State University, Columbus, and State University of New York\u2008Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","container-title":["Diabetes Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/1\/1\/34\/335291\/1-1-34.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/1\/1\/34\/335291\/1-1-34.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T23:40:18Z","timestamp":1647042018000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/care\/article\/1\/1\/34\/262\/Noneffect-of-Oral-Urinary-Copper-Ascorbic-Acid-on"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1978,1,1]]}},"URL":"https:\/\/doi.org\/10.2337\/diacare.1.1.34","relation":{},"ISSN":["0149-5992","1935-5548"],"issn-type":[{"value":"0149-5992","type":"print"},{"value":"1935-5548","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,1,1]]}}}