{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T21:19:47Z","timestamp":1698095987360},"reference-count":0,"publisher":"American Diabetes Association","issue":"8","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1990,8,1]]},"abstract":"<jats:p>The goal of this study was to describe a patient who developed insulin-dependent diabetes mellitus (IDDM) after donating a kidney to his sibling andto suggest a possible solution to prevent such an occurrence. A 42- yr-old man was found to have islet cell autoantibodies (ICAs) as part of a screeningprogram of first-degree relatives with IDDM. Two years previously, he had donated his kidney to his HLA-identical sibling with long-standing IDDM. Both oral and intravenous glucose tolerance tests demonstrated a gradual loss of insulin secretion and increasing glucose intolerance until the patient developed IDDM 6 yr after the nephrectomy. Whether the presence of ICA is an absolute contraindication to being a kidney donor could be debated. Nonetheless, ICA should be used as a screening test to identify individuals at risk for subsequent IDDM. For those found to be positive, counseling should be provided.<\/jats:p>","DOI":"10.2337\/diacare.13.8.883","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T22:51:27Z","timestamp":1173135087000},"page":"883-885","update-policy":"http:\/\/dx.doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":5,"title":["Development of IDDM After Donating Kidney to Diabetic Sibling"],"prefix":"10.2337","volume":"13","author":[{"given":"William J","family":"Riley","sequence":"first","affiliation":[{"name":"Departments of Pathology and Laboratory Medicine and Pediatrics, University of Florida\u2008Gainesville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noel K","family":"Madaren","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Laboratory Medicine and Pediatrics, University of Florida\u2008Gainesville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca P","family":"Spillar","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Laboratory Medicine and Pediatrics, University of Florida\u2008Gainesville, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","container-title":["Diabetes Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/13\/8\/883\/439901\/13-8-883.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/13\/8\/883\/439901\/13-8-883.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,12]],"date-time":"2022-03-12T11:54:06Z","timestamp":1647086046000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/care\/article\/13\/8\/883\/17055\/Development-of-IDDM-After-Donating-Kidney-to"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,8,1]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1990,8,1]]}},"URL":"https:\/\/doi.org\/10.2337\/diacare.13.8.883","relation":{},"ISSN":["0149-5992","1935-5548"],"issn-type":[{"value":"0149-5992","type":"print"},{"value":"1935-5548","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,8,1]]}}}