{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T15:25:54Z","timestamp":1779377154044,"version":"3.53.1"},"reference-count":0,"publisher":"American Diabetes Association","issue":"12","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1993,12,1]]},"abstract":"<jats:sec>\n                  <jats:title>OBJECTIVE<\/jats:title>\n                  <jats:p>To compare the influence on blood pressure, glucose, and lipid levels of a diet rich in monounsaturated fatty acids with an isocaloric, highcarbohydrate diet in 15 NIDDM subjects.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESEARCH DESIGN AND METHODS<\/jats:title>\n                  <jats:p>A crossover design with diet interventions and wash-out periods of 3 wk was applied. The patients were randomly assigned to a 3-wk treatment with a high-carbohydrate diet containing 50% of energy as carbohydrate and 30% of energy as fat (10% of energy as monounsaturated fatty acids) or an isocaloric diet with 30% of energy as carbohydrate and 50% of energy as fat (30% of energy as monounsaturated fatty acids). On the last day of the two diets, 24-h ambulatory blood pressure was measured and day profiles of glucose, hormones, and lipids were performed to a test menu rich in carbohydrates.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>RESULTS<\/jats:title>\n                  <jats:p>The diet rich in monounsaturated fat reduced daytime systolic (131 \u00b1 3 vs. 137 \u00b1 3 mmHg, P &amp;lt; 0.04) and 24-h systolic blood pressure (126 \u00b1 8 vs. 130 \u00b1 10 mmHg, P &amp;lt; 0.03) as well as daytime diastolic (78 \u00b1 2 vs. 84 \u00b1 2 mmHg, P &amp;lt; 0.02) and diurnal diastolic blood pressure (75 \u00b1 6 vs. 78 \u00b1 5 mmHg, P &amp;lt; 0.03) as compared with the high-carbohydrate diet. Evidence of lowered blood glucose levels on the high-monounsaturated diet compared with the highcarbohydrate diet were found with lower fasting blood glucose (6.1 \u00b1 0.3 vs. 6.8 \u00b1 0.5 mM, P &amp;lt; 0.05), lower average blood glucose levels (7.4 \u00b1 0.5 vs. 8.2 \u00b1 0.6 mM, P &amp;lt; 0.04), and peak blood glucose responses (9.9 \u00b1 0.6 vs. 11.3 \u00b1 0.7 mM, P &amp;lt; 0.02). The two diets had the same impact on lipid levels.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>CONCLUSIONS<\/jats:title>\n                  <jats:p>A diet rich in monounsaturated fat has beneficial effects on blood pressure and glucose metabolism, whereas no adverse effects on lipid composition in NIDDM subjects is detected.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2337\/diacare.16.12.1565","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T22:51:27Z","timestamp":1173135087000},"page":"1565-1571","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":120,"title":["Effects on Blood Pressure, Glucose, and Lipid Levels of High-Monounsaturated Fat Diet Compared With a High-Carbohydrate Diet in NIDDM Subjects"],"prefix":"10.2337","volume":"16","author":[{"given":"Ole W","family":"Rasmussen","sequence":"first","affiliation":[{"name":"Medical Department M (Diabetes and Endocrinology), Aarhus Community Hospital; Institute of Clinical Experimental Research, Aarhus University; and the Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Aarhus University Hospital\u2008Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus","family":"Thomsen","sequence":"additional","affiliation":[{"name":"Medical Department M (Diabetes and Endocrinology), Aarhus Community Hospital; Institute of Clinical Experimental Research, Aarhus University; and the Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Aarhus University Hospital\u2008Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klavs W","family":"Hansen","sequence":"additional","affiliation":[{"name":"Medical Department M (Diabetes and Endocrinology), Aarhus Community Hospital; Institute of Clinical Experimental Research, Aarhus University; and the Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Aarhus University Hospital\u2008Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margit","family":"Vesterlund","sequence":"additional","affiliation":[{"name":"Medical Department M (Diabetes and Endocrinology), Aarhus Community Hospital; Institute of Clinical Experimental Research, Aarhus University; and the Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Aarhus University Hospital\u2008Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Winther","sequence":"additional","affiliation":[{"name":"Medical Department M (Diabetes and Endocrinology), Aarhus Community Hospital; Institute of Clinical Experimental Research, Aarhus University; and the Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Aarhus University Hospital\u2008Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjeld","family":"Hermansen","sequence":"additional","affiliation":[{"name":"Medical Department M (Diabetes and Endocrinology), Aarhus Community Hospital; Institute of Clinical Experimental Research, Aarhus University; and the Department of Endocrinology and Metabolism, Aarhus Amtssygehus, Aarhus University Hospital\u2008Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","container-title":["Diabetes Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/16\/12\/1565\/441866\/16-12-1565.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/16\/12\/1565\/441866\/16-12-1565.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,12]],"date-time":"2022-03-12T11:42:47Z","timestamp":1647085367000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/care\/article\/16\/12\/1565\/17368\/Effects-on-Blood-Pressure-Glucose-and-Lipid-Levels"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,12,1]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1993,12,1]]}},"URL":"https:\/\/doi.org\/10.2337\/diacare.16.12.1565","relation":{},"ISSN":["0149-5992","1935-5548"],"issn-type":[{"value":"0149-5992","type":"print"},{"value":"1935-5548","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,12,1]]}}}