{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T05:53:39Z","timestamp":1768715619816,"version":"3.49.0"},"reference-count":14,"publisher":"American Diabetes Association","issue":"6","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2001,6,1]]},"abstract":"<jats:p>OBJECTIVE\u2014Women with polycystic ovary syndrome (PCOS) have an increased risk for developing type 2 diabetes. Few studies have assessed women with type 2 diabetes to determine the frequency of PCOS in this population.<\/jats:p>\n               <jats:p>RESEARCH DESIGN AND METHODS\u2014To determine the prevalence of PCOS among premenopausal women with type 2 diabetes, we conducted a retrospective cross-sectional prevalence study. We reviewed the medical records of all women seen in the Diabetes Clinic of the Medical College of Virginia Hospitals between January 1995 through February 2000. A diagnosis of PCOS was based on 1) oligomenorrhea, 2) hyperandrogenism (biochemical or clinical), and 3) exclusion of other related disorders.<\/jats:p>\n               <jats:p>RESULTS\u2014We reviewed the medical records of 618 women with diabetes and identified 47 women eligible for study. Of the 47 women, 30 consented to an evaluation. Of the 30 women evaluated, 8 were identified as having PCOS (6 women reported a previous PCOS diagnosis and 2 women were newly diagnosed), resulting in a prevalence of 26.7%.<\/jats:p>\n               <jats:p>CONCLUSIONS\u2014We concluded that PCOS occurs frequently among premenopausal women with type 2 diabetes.<\/jats:p>","DOI":"10.2337\/diacare.24.6.1050","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T22:51:27Z","timestamp":1173135087000},"page":"1050-1052","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":112,"title":["Prevalence of Polycystic Ovary Syndrome Among Premenopausal Women With Type 2 Diabetes"],"prefix":"10.2337","volume":"24","author":[{"given":"Heather R.","family":"Peppard","sequence":"first","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Marfori","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria J.","family":"Iuorno","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John E.","family":"Nestler","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine"},{"name":"Department of Obstetrics and Gynecology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","reference":[{"key":"2022031215050007900_R1","doi-asserted-by":"crossref","unstructured":"Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R: Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab\u200883: 3078\u20133082, 1998","DOI":"10.1210\/jc.83.9.3078"},{"key":"2022031215050007900_R2","doi-asserted-by":"crossref","unstructured":"Dunaif A, Segal KR, Futterweit W, Dobrjansky A: Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes\u200838:1165\u20131174, 1989","DOI":"10.2337\/diabetes.38.9.1165"},{"key":"2022031215050007900_R3","unstructured":"Androgen: Excess Disorders in Women. Vol 1. Azziz R, Nestler JE, Dewailly D, Eds. Philadelphia, PA, Lippincott-Raven, 1997"},{"key":"2022031215050007900_R4","doi-asserted-by":"crossref","unstructured":"Puavilai G, Chanprasertyotin S, Sriphrapradaeng A: Diagnostic criteria for diabetes mellitus and other categories of glucose intolerance: 1997 criteria by the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO consultation criteria, and 1985 WHO criteria. World Health Organization. Diabetes Res Clin Pract\u200844:21\u201326, 1999","DOI":"10.1016\/S0168-8227(99)00008-X"},{"key":"2022031215050007900_R5","unstructured":"Achard MC, Thiers MJ: Le virilisme pilaire et son association a l\u2019insuffisance glycolitique (diabe\u0300te des femmes a\u0300 barbe). Bull Acad Nat Med\u200886:51\u201385, 1921"},{"key":"2022031215050007900_R6","doi-asserted-by":"crossref","unstructured":"Ehrmann DA, Barnes RB, Rosenfield RL, Cavaghan MK, Imperial J: Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care\u200822:141\u2013146, 1999","DOI":"10.2337\/diacare.22.1.141"},{"key":"2022031215050007900_R7","doi-asserted-by":"crossref","unstructured":"Legro RS, Kunselman AR, Dodson WC, Dunaif A: Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. J Clin Endocrinol Metab\u200884:165\u2013169, 1999","DOI":"10.1210\/jc.84.1.165"},{"key":"2022031215050007900_R8","doi-asserted-by":"crossref","unstructured":"Conn JJ, Jacobs HS, Conway GS: The prevalence of polycystic ovaries in women with type 2 diabetes mellitus. Clin Endocrinol (Oxf\u200852:81\u201386, 2000","DOI":"10.1046\/j.1365-2265.2000.00884.x"},{"key":"2022031215050007900_R9","doi-asserted-by":"crossref","unstructured":"Hatch R, Rosenfield RL, Kim MH, Tredway D: Hirsutism: implications, etiology, and management. Am J Obstet Gynecol\u2008140:815\u2013830, 1981","DOI":"10.1016\/0002-9378(81)90746-8"},{"key":"2022031215050007900_R10","unstructured":"Zawadzki JK, Dunaif A: Diagnostic Criteria for Polycystic Ovary Syndrome: Towards a Rational Approach. Dunaif A, Givens JR, Haseltine FP, Merriam GR, Eds. Boston, MA, Blackwell Scientific, 1992, p. 377\u2013384"},{"key":"2022031215050007900_R11","doi-asserted-by":"crossref","unstructured":"Polson DW, Adams J, Wadsworth J, Franks S: Polycystic ovaries: a common finding in normal women. Lancet\u20081:870\u2013872, 1988","DOI":"10.1016\/S0140-6736(88)91612-1"},{"key":"2022031215050007900_R12","doi-asserted-by":"crossref","unstructured":"Moghetti P, Castello R, Negri C, Tosi F, Perrone F, Caputo M, Zanolin E, Muggeo M: Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: a randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation. J Clin Endocrinol Metab\u200885:139\u2013146, 2000","DOI":"10.1210\/jc.85.1.139"},{"key":"2022031215050007900_R13","doi-asserted-by":"crossref","unstructured":"Hasegawa I, Murakawa H, Suzuki M, Yamamoto Y, Kurabayashi T, Tanaka K: Effect of troglitazone on endocrine and ovulatory performance in women with insulin resistance-related polycystic ovary syndrome. Fertil Steril\u200871:323\u2013327, 1999","DOI":"10.1016\/S0015-0282(98)00454-3"},{"key":"2022031215050007900_R14","doi-asserted-by":"crossref","unstructured":"Nestler JE, Jakubowicz DJ, Evans WS, Pasquali R: Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome. N Engl J Med\u2008338:1876\u20131880, 1998","DOI":"10.1056\/NEJM199806253382603"}],"container-title":["Diabetes Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/24\/6\/1050\/587811\/1050.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/diabetesjournals.org\/care\/article-pdf\/24\/6\/1050\/587811\/1050.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,12]],"date-time":"2022-03-12T15:05:13Z","timestamp":1647097513000},"score":1,"resource":{"primary":{"URL":"https:\/\/diabetesjournals.org\/care\/article\/24\/6\/1050\/22489\/Prevalence-of-Polycystic-Ovary-Syndrome-Among"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6,1]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2001,6,1]]}},"URL":"https:\/\/doi.org\/10.2337\/diacare.24.6.1050","relation":{},"ISSN":["0149-5992","1935-5548"],"issn-type":[{"value":"0149-5992","type":"print"},{"value":"1935-5548","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,6,1]]}}}