{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T12:18:09Z","timestamp":1700396289352},"reference-count":22,"publisher":"American Diabetes Association","issue":"9","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2001,9,1]]},"abstract":"<jats:p>OBJECTIVE\u2014To study the influence of position changes on 24-h ambulatory blood pressure (ABP) in normotensive or mildly hypertensive normoalbuminuric patients with type 1 diabetes.<\/jats:p>\n               <jats:p>RESEARCH DESIGN AND METHODS\u2014A cross-sectional evaluation of patients was staged according to the duration of diabetes (DD) and the presence of microangiopathy. We recruited 37 patients (30 men and 7 women), aged 38 \u00b1 12 years, who were normotensive or mildly hypertensive (diastolic blood pressure [DBP] &amp;lt;105 mmHg) and free of antihypertensive treatment and microalbuminuria. They were included according to DD (group 1, &amp;lt;5 years; group 2, \u226510 years). An additional group of seven diabetic patients with microalbuminuria and mild untreated hypertension was also investigated. We recorded 24-h ambulatory blood pressure every 15 min with a position sensor, which allowed for the discrimination between standing or supine\/sitting position in the patient.<\/jats:p>\n               <jats:p>RESULTS\u2014Mean daytime (10:00 a.m. to 8:00 p.m.) ABP in supine\/sitting position did not significantly differ between groups 1 and 2. However, standing ambulatory systolic blood pressure (ASBP) and ambulatory DBP (ADBP) were significantly higher than supine\/sitting ASBP and ADBP in group 1 (\u0394SBP 4 \u00b1 5, \u0394DPB 4 \u00b1 6 mmHg, P &amp;lt; 0.01) but not in group 2 (\u0394SBP 2 \u00b1 8, \u0394DBP 2 \u00b1 4 mmHg, P = NS). Patients free of microangiopathy presented with significantly higher ABP in standing position than in sitting\/lying position, whereas patients with retinopathy and\/or nephropathy exhibited no significant increase of ABP during standing.<\/jats:p>\n               <jats:p>CONCLUSION\u2014The monitoring of position during ambulatory measurement of blood pressure in type 1 diabetic patients shows different patterns in relation to disease duration and the presence of microangiopathy.<\/jats:p>","DOI":"10.2337\/diacare.24.9.1624","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T22:51:27Z","timestamp":1173135087000},"page":"1624-1628","update-policy":"http:\/\/dx.doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":4,"title":["Variations of Ambulatory Blood Pressure With Position in Patients With Type 1 Diabetes"],"prefix":"10.2337","volume":"24","author":[{"given":"Pierre Y.","family":"Benhamou","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Grenoble University Hospital, Grenoble, and the"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandrine","family":"Mouret","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Cardiology, Grenoble University Hospital, Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean L.","family":"Quesada","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Cardiology, Grenoble University Hospital, Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Boizel","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Grenoble University Hospital, Grenoble, and the"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean P.","family":"Baguet","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Cardiology, Grenoble University Hospital, Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serge","family":"Halimi","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Grenoble University Hospital, Grenoble, and the"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean M.","family":"Mallion","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Cardiology, Grenoble University Hospital, Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","reference":[{"key":"2022031214365598100_R1","doi-asserted-by":"crossref","unstructured":"Hansen KW, Christensen CK, Andersen PH, Pedersen MM, Christiansen JS, Mogensen CE: Ambulatory blood pressure in microalbuminuric type 1 diabetic patients. 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