{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T02:03:38Z","timestamp":1791425018699,"version":"4.3.3"},"reference-count":48,"publisher":"American Diabetes Association","issue":"9","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2002,9,1]]},"abstract":"<jats:p>OBJECTIVE\u2014This article tests the hypothesis that women with impaired glucose tolerance (IGT) have the same pregnancy outcomes as those of their counterparts with normal glucose tolerance.<\/jats:p>\n               <jats:p>RESEARCH DESIGN AND METHODS\u2014From December 1998 to December 1999, 84 of 90 antenatal care base units (ACBUs) under the Tianjin Antenatal Care Network in China participated in the first screening program for gestational diabetes mellitus (GDM). A total of 9,471 pregnant women under the care of participating ACBUs were screened. Of the women screened, 154 were positive for IGT. Of the 154 women, 102 opted for conventional obstetric care. The comparison group was 302 women of normal glucose tolerance (NGT). The initial screening consisted of a 50-g 1-h glucose test, and was carried out at 26\u201330 gestational weeks. Women with a serum glucose \u22657.8 mmol\/l were followed up with a 75-g 2-h oral glucose tolerance test. The World Health Organization\u2019s diagnostic criteria for GDM were used.<\/jats:p>\n               <jats:p>RESULTS\u2014Women with IGT were at increased risk for premature rupture of membranes (P-ROM) (odds ratio [OR] 10.07; 95% CI 2.90\u201334.93); preterm birth (6.42; 1.46\u201328.34); breech presentation (3.47; 1.11\u201310.84); and high birth weight (90th percentile or 4,000 g) (2.42; 1.07\u20135.46); adjusting for maternal age, pregravid BMI, hospital levels, and other confounding factors.<\/jats:p>\n               <jats:p>CONCLUSIONS\u2014The presence of IGT in pregnancy is predictive of poor pregnancy outcomes.<\/jats:p>","DOI":"10.2337\/diacare.25.9.1619","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T22:51:27Z","timestamp":1173135087000},"page":"1619-1624","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":136,"title":["Women With Impaired Glucose Tolerance During Pregnancy Have Significantly Poor Pregnancy Outcomes"],"prefix":"10.2337","volume":"25","author":[{"given":"Xilin","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Rural Health, University of Melbourne, Melbourne, Australia"},{"name":"Tianjin Centre of Disease Control and Prevention, Tianjin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridget","family":"Hsu-Hage","sequence":"additional","affiliation":[{"name":"Department of Rural Health, University of Melbourne, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Tianjin Institute for Women\u2019s Health, Tianjin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuiping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Tianjin Institute for Women\u2019s Health, Tianjin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanni","family":"Zhang","sequence":"additional","affiliation":[{"name":"Tianjin Institute for Women\u2019s Health, Tianjin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changjun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Tianjin Institute for Women\u2019s Health, Tianjin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1167","reference":[{"key":"2022031214440265100_R1","doi-asserted-by":"crossref","unstructured":"Mestman J: Outcome of diabetes screening in pregnancy and perinatal morbidity in infants of mothers with mild impairment in glucose tolerance. 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