{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T21:03:56Z","timestamp":1776891836540,"version":"3.51.2"},"reference-count":17,"publisher":"American Diabetes Association","issue":"8","content-domain":{"domain":["diabetesjournals.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2003,8,1]]},"abstract":"<jats:p>OBJECTIVE\u2014Microalbuminuria is a recognized risk factor for increased mortality and renal failure in type 1 diabetes. Whether it remains a powerful predictor in patients with a long duration of type 1 diabetes is not known. We ascertained the prognostic significance of abnormal urinary albumin excretion in a cohort of patients with at least 30 years of type 1 diabetes.<\/jats:p>\n               <jats:p>RESEARCH DESIGN AND METHODS\u2014A total of 190 patients with a disease duration of type 1 diabetes of at least 30 years with baseline and 5 years of follow-up.<\/jats:p>\n               <jats:p>RESULTS\u2014At baseline 66% were normoalbuminuric, and at 5 years 11% of this cohort had died. Of the 22% who were microalbuminuric at baseline, 26% had died, and of the 8% with persistent proteinuria at baseline, 44% had died. Of the 4% with end-stage renal failure at baseline, 71% had died within 5 years. Death was attributable to a cardiovascular cause in two-thirds of the cases in all groups.<\/jats:p>\n               <jats:p>CONCLUSIONS\u2014Even in those with a long duration of type 1 diabetes, the presence of abnormal urinary excretion remains a powerful predictor of increased mortality.<\/jats:p>","DOI":"10.2337\/diacare.26.8.2389","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T22:51:27Z","timestamp":1173135087000},"page":"2389-2391","update-policy":"https:\/\/doi.org\/10.2337\/ada-journal-policies","source":"Crossref","is-referenced-by-count":51,"title":["Microalbuminuria and Mortality in Long-Duration Type 1 Diabetes"],"prefix":"10.2337","volume":"26","author":[{"given":"Kate V.","family":"Allen","sequence":"first","affiliation":[{"name":"From the Department of Diabetes, Royal Infimary, Edinburgh, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James D.","family":"Walker","sequence":"additional","affiliation":[{"name":"From the Department of Diabetes, Royal Infimary, Edinburgh, U.K."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1167","reference":[{"key":"2022031215274076100_R1","doi-asserted-by":"crossref","unstructured":"Andersen AR, Christiansen JS, Andersen JK, Kreiner S, Deckert T: Diabetic nephropathy in type 1 (insulin-dependent) diabetes: an epidemiological study. 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