{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T14:51:10Z","timestamp":1769093470960,"version":"3.49.0"},"reference-count":27,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T00:00:00Z","timestamp":1706486400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ActaO"],"abstract":"<jats:p>Background and purpose: We aimed to evaluate the long-term predictive value of radiographic abnormality and\/or hip pain assessed 5 years following primary total hip arthroplasty (THA) and the occurrence of revision for aseptic loosening between 5 and 25 years postoperatively.Patients and methods:\u00a0We included all primary THAs performed between 1996 and 2011 (same uncemented cup, polyethylene-ceramic bearing, 28 mm head, cemented stem) and prospectively enrolled in the institutional registry, for whom baseline and follow-up radiographs were available. At 5 years radiographically we assessed femoral osteolysis and\/or stem migration. Pain was evaluated with the Harris Hip pain subscore. Kaplan\u2013Meier survival and Cox regression analyses were performed.Results: 1,317 primary THAs were included. 25 THAs (2%) were revised for aseptic stem loosening. Any abnormal radiographic sign at 5 years was present in 191 THAs (14%). Occasional hip pain was reported by 20% and slight to severe pain by 12% of patients at 5 years. In patients &lt; 60 years, 10 of the 12 later revised for aseptic stem loosening had abnormal radiographs at 5 years vs. 5 of the 13 later revised in those \u2265 60 years. Hazard ratios (HR) were 34 (95% confidence interval [CI] 7\u2013155) in younger vs. 4 (CI 1\u201311) in the older group. HR for association of hip pain at 5 years with future revision was 3 (CI 1\u20135).Conclusion:\u00a0The presence of abnormal radiographic signs 5 years after THA was strongly associated with later revision for aseptic stem loosening, especially in patients &lt; 60 years. The association between pain at 5 years and future revision was much weaker.<\/jats:p>","DOI":"10.2340\/17453674.2023.26190","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T12:45:07Z","timestamp":1706532307000},"page":"32-38","source":"Crossref","is-referenced-by-count":4,"title":["Radiographic signs and hip pain 5 years after THA with a cemented stem predict future revision for aseptic loosening: a prospective cohort study"],"prefix":"10.2340","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6905-6120","authenticated-orcid":false,"given":"Anne","family":"L\u00fcbbeke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1781-9453","authenticated-orcid":false,"given":"Christophe","family":"Barea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthieu","family":"Zingg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Lauper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didier","family":"Hannouche","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Garavaglia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1183","published-online":{"date-parts":[[2024,1,29]]},"reference":[{"key":"47588","doi-asserted-by":"publisher","DOI":"10.1007\/s11999.0000000000000036"},{"key":"47589","doi-asserted-by":"publisher","DOI":"10.1302\/2058-5241.3.170068"},{"key":"47590","unstructured":"Feng X, Gu J, Zhou X. Primary total hip arthroplasty failure: aseptic loosening remains the most common cause of revision. Am J Transl Res 2022; 14(10): 7080\u20139."},{"key":"47591","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-13-251"},{"key":"47592","doi-asserted-by":"publisher","DOI":"10.1080\/17453670610013493"},{"key":"47593","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200012000-00005"},{"key":"47594","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2010.08.007"},{"key":"47595","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)33177-0"},{"key":"47596","doi-asserted-by":"publisher","DOI":"10.1302\/2046-3758.56.2000568"},{"key":"47597","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.81B2.0810273"},{"key":"47598","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-016-4857-5"},{"key":"47599","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.79B4.0790583"},{"key":"47600","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.92B3.22913"},{"key":"47601","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-017-3711-z"},{"key":"47602","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-013-2880-3"},{"key":"47603","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.88B10.17399"},{"key":"47604","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2017.02.052"},{"key":"47605","doi-asserted-by":"publisher","DOI":"10.1177\/1536867X1001000303"},{"key":"47606","doi-asserted-by":"publisher","DOI":"10.3109\/17453674.2015.1104153"},{"key":"47607","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199008000-00022"},{"key":"47608","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-020-04910-5"},{"key":"47609","doi-asserted-by":"publisher","DOI":"10.3109\/17453674.2015.1043832"},{"key":"47610","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-016-1106-8"},{"key":"47611","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.85B1.13367"},{"key":"47612","doi-asserted-by":"publisher","DOI":"10.1002\/jor.23356"},{"key":"47613","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2023.103746"},{"key":"47614","doi-asserted-by":"publisher","DOI":"10.2340\/17453674.2023.11656"}],"container-title":["Acta Orthopaedica"],"original-title":[],"link":[{"URL":"https:\/\/actaorthop.org\/actao\/article\/download\/26190\/45121","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaorthop.org\/actao\/article\/download\/26190\/45164","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaorthop.org\/actao\/article\/download\/26190\/45165","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaorthop.org\/actao\/article\/download\/26190\/45121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T02:02:58Z","timestamp":1734573778000},"score":1,"resource":{"primary":{"URL":"https:\/\/actaorthop.org\/actao\/article\/view\/26190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,29]]},"references-count":27,"URL":"https:\/\/doi.org\/10.2340\/17453674.2023.26190","relation":{},"ISSN":["1745-3682","1745-3674"],"issn-type":[{"value":"1745-3682","type":"electronic"},{"value":"1745-3674","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1,29]]}}}