{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T11:40:40Z","timestamp":1780486840469,"version":"3.54.1"},"reference-count":21,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:00:00Z","timestamp":1758067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ActaO"],"abstract":"<jats:p>Background and purpose:\u00a0Limited data exist on venous thromboembolism (VTE) and mortality risk in patients undergoing primary total hip (THA) or knee arthroplasty (TKA) following recent COVID-19 infection. We aimed to evaluate whether the timing of COVID-19 infection affects postoperative VTE and mortality risk after THA or TKA.Methods:\u00a0Adult Kaiser Permanente Northern California members undergoing elective THA or TKA from 2020\u20132022 were identified using internal procedure codes. 33,520 patients with or without SARS-CoV-2 within 6 months preoperatively were compared. Multivariate Poisson regression was used to calculate incidence rate ratios (RRs) adjusted for demographics, comorbidities, and Covid vaccination status. The primary outcome was 90-day VTE (deep venous thrombosis or pulmonary embolism). The secondary outcome was 90-day mortality.Results:\u00a0Among patients with recent COVID-19, the 90-day VTE rate was 0.3%, and the mortality rate was 2.5%. Recent COVID-19 within 6 to 12 weeks preoperatively did not significantly increase 90-day VTE risk (RR 1.0, 95% confidence interval [CI] 0.38\u20132.8) but was associated with increased 90-day mortality risk (RR 3.1, CI 1.7\u20135.4).Conclusion:\u00a0Recent COVID-19 infection did not significantly impact VTE risk after THA or TKA. However, infection within 6 to 12 weeks preoperatively was associated with increased 90-day mortality.<\/jats:p>","DOI":"10.2340\/17453674.2025.44481","type":"journal-article","created":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T19:19:49Z","timestamp":1758136789000},"source":"Crossref","is-referenced-by-count":2,"title":["Risk of perioperative mortality and venous thromboembolism after total hip or knee arthroplasty with recent COVID-19 infection: an observational study from the Kaiser Permanente Northern California Database"],"prefix":"10.2340","volume":"96","author":[{"given":"Aidan T","family":"Morrell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryland P","family":"Kagan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mackenzie","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham J","family":"DeKeyser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew L","family":"Avins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lusine X","family":"Gigoyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John S","family":"Cox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2025,9,17]]},"reference":[{"key":"126840","unstructured":"U.S. Centers for Disease Control & Infection. 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Trends in deep vein thrombosis prophylaxis and deep vein thrombosis rates after total hip and knee arthroplasty. J Am Acad Orthop Surg 2018; 26(19): 698-705. doi: 10.5435\/JAAOS-D-17-00235. Erratum in: J Am Acad Orthop Surg 2018; 26(23): 852. doi: 10.5435\/JAAOS-D-18-00635.","DOI":"10.5435\/JAAOS-D-17-00235"},{"key":"126845","doi-asserted-by":"crossref","unstructured":"Narang A, Chan G, Aframian A, Ali Z, Carr A, Goodier H, et al. Thirty-day mortality following surgical management of hip fractures during the COVID-19 pandemic: findings from a prospective multi-centre UK study. Int Orthop 2021; 45(1): 23-31. doi: 10.1007\/s00264-020-04739-y. Epub 2020. Erratum in: Int Orthop. 2020; 44(12): 2819. doi: 10.1007\/s00264-020-04824-2.","DOI":"10.1007\/s00264-020-04824-2"},{"key":"126846","doi-asserted-by":"crossref","unstructured":"Wang K C, Xiao R, Cheung Z B, Barbera J P, Forsh D A. Early mortality after hip fracture surgery in COVID-19 patients: a systematic review and meta-analysis. 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