{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T07:45:04Z","timestamp":1792395904948,"version":"4.4.0"},"reference-count":34,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ActaO"],"abstract":"<jats:p>Background and purpose:\u00a0Alcohol increases the risk of falls and complications, but data on alcohol intake among trauma patients is unreliable. Excessive alcohol use can contribute to excess frailty and confusion in frail individuals and increase fall risk in otherwise robust older people. Phosphatidylethanol (PEth) is a biomarker accumulating through repeated alcohol intake, i.e., suitable for screening long-term consumption. Our primary aim was to describe alcohol consumption in older individuals admitted after a fall-related fracture. Our secondary, exploratory aims were to investigate the association between alcohol, frailty, and short-term clinical outcomes in these individuals.Methods:\u00a0This prospective observational cohort study included those \u2265 65 years admitted due to acute fall-related fracture February 1, 2023\u2013August 31, 2024. PEth was taken at admission. Predefined norm values classified low\/no consumption as &lt; 0.05, intermediate 0.05\u20130.30 and hazardous consumption &gt; 0.30 \u00b5mol\/L. Frailty status was assessed by the Clinical Frailty Scale (CFS). Our secondary aim was addressed using multivariable logistic regression on a propensity score-matched cohort.Results:\u00a0Of the 505 patients included, 13% had PEth indicating hazardous consumption, 8.9% intermediate consumption, and 78% had low\/no consumption. Of the non-frail patients, 18% had hazardous and 11% intermediate consumption. 19% of all women and 29% of all men had continuous alcohol consumption (defined as PEth \u2265 0.05 \u00b5mol\/L). In the matched cohort, alcohol consumption was associated with a higher odds ratio (OR) of hyponatremia (OR 2.3, 95% confidence interval [CI] 1.1\u20134.5, P = 0.02). A trend towards lower odds of 90-day mortality (OR 0.2, CI 0.1\u20131.0, P = 0.05) was seen.Conclusion:\u00a0A minimum of 1\/5 older patients with fall-related fractures have continuous alcohol consumption. Non-frail patients had a higher intake than frail individuals. Alcohol consumption was associated with higher odds of hyponatremia. Otherwise, no apparent negative effects were identified in the short term.<\/jats:p>","DOI":"10.2340\/17453674.2026.46961","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T06:12:17Z","timestamp":1792390337000},"source":"Crossref","is-referenced-by-count":0,"title":["Alcohol use is common in older patients with fall-related fractures: a secondary analysis from a prospective cohort study using PEth as an objective assessment of consumption"],"prefix":"10.2340","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6556-4320","authenticated-orcid":false,"given":"Cecilia","family":"Rogmark","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3296-7083","authenticated-orcid":false,"given":"Linnea","family":"Malmgren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Holmgren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c5sa","family":"Magnusson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1900-694X","authenticated-orcid":false,"given":"Helmi-Sisko","family":"Pyrh\u00f6nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2026,10,19]]},"reference":[{"key":"171350","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-023-03738-z"},{"key":"171351","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2020.06.020"},{"key":"171352","unstructured":"Pfortmueller C A, Lindner G, Exadaktylos A K. Reducing fall risk in the elderly: risk factors and fall prevention, a systematic review. Minerva Med 2014; 105(4): 275-81. PMID: 24867188."},{"key":"171353","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2010.02.011"},{"key":"171354","unstructured":"The Swedish Public Health Authority. Alcohol, risk [excessive] use; 2022 [in Swedish]. Available from: https:\/\/www.folkhalsomyndigheten.se\/fu-alkohol"},{"key":"171355","doi-asserted-by":"publisher","DOI":"10.1111\/acer.13893"},{"key":"171356","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182988d59"},{"key":"171357","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2024.111765"},{"key":"171358","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2006.00837.x"},{"key":"171359","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2020.1822531"},{"key":"171360","doi-asserted-by":"publisher","DOI":"10.1111\/acer.14611"},{"key":"171361","doi-asserted-by":"publisher","DOI":"10.1080\/00365513.2023.2253734"},{"key":"171362","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agz064"},{"key":"171363","doi-asserted-by":"publisher","DOI":"10.1111\/acer.12883"},{"key":"171364","doi-asserted-by":"publisher","DOI":"10.1002\/dta.3340"},{"key":"171365","doi-asserted-by":"publisher","DOI":"10.1111\/1556-4029.13874"},{"key":"171366","unstructured":"Dillstr\u00f6m I, Ahmadul K, Metzner C, Kivipelto M, Bostr\u00f6m A, Religa D, et al. Sk\u00f6rhetsskala kan bidra n\u00e4r v\u00e5rdtid och d\u00f6dsrisk bed\u00f6ms [Frailty Scale can contribute to the evaluation of length of hospital stay and risk of death]. L\u00e4kartidningen 2021; 118."},{"key":"171367","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.090222"},{"key":"171368","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0180132"},{"key":"171369","doi-asserted-by":"publisher","DOI":"10.1080\/07317115.2017.1364681"},{"key":"171370","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6874-13-36"},{"key":"171371","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2024.101020"},{"key":"171372","doi-asserted-by":"publisher","DOI":"10.1097\/MCO.0b013e3282f30564"},{"key":"171373","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2012.01.022"},{"key":"171374","doi-asserted-by":"publisher","DOI":"10.15288\/jsa.2002.63.372"},{"key":"171375","doi-asserted-by":"publisher","DOI":"10.2340\/17453674.2022.2482"},{"key":"171376","doi-asserted-by":"publisher","DOI":"10.5301\/hipint.5000156"},{"key":"171377","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocl.2017.06.002"},{"key":"171378","doi-asserted-by":"publisher","DOI":"10.4172\/2329-6488.1000185"},{"key":"171379","doi-asserted-by":"publisher","DOI":"10.1308\/003588413X13511609954815"},{"key":"171380","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ph.1900757"},{"key":"171381","doi-asserted-by":"publisher","DOI":"10.1111\/ajad.13516"},{"key":"171382","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.15100"},{"key":"171383","doi-asserted-by":"publisher","DOI":"10.1111\/acer.14958"}],"container-title":["Acta Orthopaedica"],"original-title":[],"link":[{"URL":"https:\/\/actaorthop.org\/actao\/article\/download\/46961\/55851","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaorthop.org\/actao\/article\/download\/46961\/55881","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaorthop.org\/actao\/article\/download\/46961\/55882","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/actaorthop.org\/actao\/article\/download\/46961\/55851","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T07:28:56Z","timestamp":1792394936000},"score":1,"resource":{"primary":{"URL":"https:\/\/actaorthop.org\/actao\/article\/view\/46961"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,19]]},"references-count":34,"URL":"https:\/\/doi.org\/10.2340\/17453674.2026.46961","relation":{},"ISSN":["1745-3682","1745-3674"],"issn-type":[{"value":"1745-3682","type":"electronic"},{"value":"1745-3674","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10,19]]}}}