{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T18:25:30Z","timestamp":1791570330559,"version":"4.3.4"},"reference-count":71,"publisher":"Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Derm Venereol"],"abstract":"<jats:p>Dermatitis herpetiformis is a blistering autoimmune skin disease, and a cutaneous manifestation of coeliac disease. The burden of coeliac disease is increased especially in females, but studies concerning sex differences in patients with long-term treated dermatitis herpetiformis are scarce. This questionnaire study compared adherence to a gluten-free diet, clinical symptoms and well-being between females and males in a cohort of 237 long-term treated (median 24 years) patients with dermatitis herpetiformis. Females had better adherence to a gluten-free diet (p\u2009=\u20090.022) and they used dapsone significantly less often at the time of the study than did males (4% vs 13%, p\u2009=\u20090.017). The occurrence of skin symptoms was equal in both sexes, but dermatological quality of life was lower in females (p\u2009=\u20090.024), and gastrointestinal symptoms were more severe among females with dermatitis herpetiformis than among males (p\u2009=\u20090.027). In conclusion, long-term treated female patients with dermatitis herpetiformis have better adherence to a gluten-free diet, but they also experience more severe clinical symptoms compared with males.<\/jats:p>","DOI":"10.2340\/actadv.v102.1072","type":"journal-article","created":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T07:52:47Z","timestamp":1649404367000},"page":"adv00713","source":"Crossref","is-referenced-by-count":6,"title":["Sex-differences in Gluten-free Dietary Adherence and Clinical Symptoms in Patients with Long-term Treated Dermatitis Herpetiformis"],"prefix":"10.2340","volume":"102","author":[{"given":"Camilla","family":"Pasternack","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaisa","family":"Hervonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eriika","family":"Mansikka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Reunala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katri","family":"Kaukinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teea","family":"Salmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2022,5,16]]},"reference":[{"key":"18694","doi-asserted-by":"crossref","unstructured":"Salmi T, Hervonen K. 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