{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T19:13:21Z","timestamp":1782933201153,"version":"3.54.5"},"reference-count":56,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T00:00:00Z","timestamp":1679270400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Derm Venereol"],"abstract":"<jats:p>Intramuscular capillary-type haemangiomas (ICTH) are rare vascular anomalies that can easily be misdiagnosed as other entities. A systematic review was performed of all cases of ICTH in the literature since its first description in 1972. An adjudication committee reviewed cases to include only ICTHs. Among 1,143 reports screened, 43 were included, involving 75 patients. The most frequent differential diagnosis was intramuscular venous malformations. The mean age of patients at diagnosis was 21.2 years. ICTH was mainly described as a gradually increasing mass (81.8%), painless (73.9%), that could occur anywhere in the body but most frequently on the head and neck (44.0%). Magnetic resonance imaging (MRI) was mainly used for diagnosis (69.1%) and displayed specific features. The most frequent treatment was complete surgical removal (73.9%), which could be preceded by embolization, and led to complete remission without recurrence in all but 1 case.<\/jats:p>","DOI":"10.2340\/actadv.v103.4432","type":"journal-article","created":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T14:28:49Z","timestamp":1679322529000},"page":"adv00893","source":"Crossref","is-referenced-by-count":6,"title":["Characteristics, Natural Course and Treatment of Intramuscular Capillary-type Haemangioma: A Systematic Literature Review"],"prefix":"10.2340","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6463-3187","authenticated-orcid":false,"given":"Jordan","family":"Orly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annouk","family":"Bisdorff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline","family":"Joly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afi-Emili\u00e8ne","family":"Edee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsa","family":"Tavernier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4533-4296","authenticated-orcid":false,"given":"Denis","family":"Herbreteau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3508-2539","authenticated-orcid":false,"given":"Olivia","family":"Boccara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9768-9788","authenticated-orcid":false,"given":"Michel","family":"Wassef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3734-810X","authenticated-orcid":false,"given":"Annabel","family":"Maruani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2023,3,20]]},"reference":[{"key":"29403","doi-asserted-by":"crossref","unstructured":"Allen PW, Enzinger FM. Hemangioma of skeletal muscle. An analysis of 89 cases. Cancer 1972; 29: 8-22.","DOI":"10.1002\/1097-0142(197201)29:1<8::AID-CNCR2820290103>3.0.CO;2-A"},{"key":"29404","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1002\/1097-0142(197201)29:1<8::AID-CNCR2820290103>3.0.CO;2-A","DOI":"10.1002\/1097-0142(197201)29:1<8::AID-CNCR2820290103>3.0.CO;2-A"},{"key":"29405","doi-asserted-by":"crossref","unstructured":"Yilmaz S, Kozakewich HP, Alomari AI, Fishman SJ, Mulliken JB, Chaudry G. Intramuscular capillary-type hemangioma: radiologic-pathologic correlation. Pediatr Radiol 2014; 44: 558-565.","DOI":"10.1007\/s00247-014-2876-5"},{"key":"29406","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s00247-014-2876-5","DOI":"10.1007\/s00247-014-2876-5"},{"key":"29407","doi-asserted-by":"crossref","unstructured":"Griffin N, Khan N, Thomas JM, Fisher C, Moskovic EC. The radiological manifestations of intramuscular haemangiomas in adults: magnetic resonance imaging, computed tomography and ultrasound appearances. Skeletal Radiol 2007; 36: 1051-1059.","DOI":"10.1007\/s00256-007-0375-6"},{"key":"29408","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s00256-007-0375-6","DOI":"10.1007\/s00256-007-0375-6"},{"key":"29409","doi-asserted-by":"crossref","unstructured":"Beham A, Fletcher CD. Intramuscular angioma: a clinicopathological analysis of 74 cases. Histopathology 1991; 18: 53-59.","DOI":"10.1111\/j.1365-2559.1991.tb00814.x"},{"key":"29410","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/j.1365-2559.1991.tb00814.x","DOI":"10.1111\/j.1365-2559.1991.tb00814.x"},{"key":"29411","doi-asserted-by":"crossref","unstructured":"DeGiovanni JC, Simmonds J, Lang-Orsini M, Lee A. Recurrent intramuscular hemangioma (infiltrating angiolipoma) of the lower lip: a case report and review of the literature. Ear Nose Throat J 2022; 101: 306-311.","DOI":"10.1177\/0145561320957759"},{"key":"29412","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1177\/0145561320957759","DOI":"10.1177\/0145561320957759"},{"key":"29413","doi-asserted-by":"crossref","unstructured":"Hein KD, Mulliken JB, Kozakewich HPW, Upton J, Burrows PE. Venous malformations of skeletal muscle. Plast Reconstr Surg 2002; 110: 1625-1635.","DOI":"10.1097\/00006534-200212000-00001"},{"key":"29414","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/00006534-200212000-00001","DOI":"10.1097\/00006534-200212000-00001"},{"key":"29415","doi-asserted-by":"crossref","unstructured":"Ros de San Pedro J, Cuartero P\u00e9rez B, Ferri \u00d1\u00edguez B, Villanueva San Vicente V. Arteriovenous malformations of the temporalis muscle: a comprehensive review. Oper Neurosurg 2018; 14: 325-340.","DOI":"10.1093\/ons\/opx149"},{"key":"29416","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1093\/ons\/opx149","DOI":"10.1093\/ons\/opx149"},{"key":"29417","doi-asserted-by":"crossref","unstructured":"Choi JH, Ro JY. The 2020 WHO classification of tumors of soft tissue: selected changes and new entities. Adv Anat Pathol 2021; 28: 44-58.","DOI":"10.1097\/PAP.0000000000000284"},{"key":"29418","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/PAP.0000000000000284","DOI":"10.1097\/PAP.0000000000000284"},{"key":"29419","doi-asserted-by":"crossref","unstructured":"Hoeft S, Luettges J, Werner JA. Infiltrating angiolipoma of the M. temporalis. Auris Nasus Larynx 2000; 27: 265-269.","DOI":"10.1016\/S0385-8146(99)00075-9"},{"key":"29420","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/S0385-8146(99)00075-9","DOI":"10.1016\/S0385-8146(99)00075-9"},{"key":"29421","doi-asserted-by":"crossref","unstructured":"Kurek KC, Howard E, Tennant LB, Upton J, Alomari AI, Burrows PE, et al. PTEN hamartoma of soft tissue: a distinctive lesion in PTEN syndromes Am J Surg Pathol 2012; 36: 671-687.","DOI":"10.1097\/PAS.0b013e31824dd86c"},{"key":"29422","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/PAS.0b013e31824dd86c","DOI":"10.1097\/PAS.0b013e31824dd86c"},{"key":"29423","doi-asserted-by":"crossref","unstructured":"Stein-Wexler R. Pediatric soft tissue sarcomas. Semin Ultrasound CT MR 2011; 32: 470-488.","DOI":"10.1053\/j.sult.2011.03.006"},{"key":"29424","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1053\/j.sult.2011.03.006","DOI":"10.1053\/j.sult.2011.03.006"},{"key":"29425","doi-asserted-by":"crossref","unstructured":"Wassef M, Blei F, Adams D, Alomari A, Baselga E, Berenstein A, et al. Vascular anomalies classification: recommendations from the International Society for the Study of Vascular Anomalies. Pediatrics 2015; 136: e203-204.","DOI":"10.1542\/peds.2014-3673"},{"key":"29426","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1542\/peds.2014-3673","DOI":"10.1542\/peds.2014-3673"},{"key":"29427","doi-asserted-by":"crossref","unstructured":"Couto JA, Huang AY, Konczyk DJ, Goss JA, Fishman SJ, Mulliken JB, et al. Somatic MAP2K1 mutations are associated with extracranial arteriovenous malformation. Am J Hum Genet 2017; 100: 546-554.","DOI":"10.1016\/j.ajhg.2017.01.018"},{"key":"29428","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.ajhg.2017.01.018","DOI":"10.1016\/j.ajhg.2017.01.018"},{"key":"29429","doi-asserted-by":"crossref","unstructured":"Al-Olabi L, Polubothu S, Dowsett K, Andrews KA, Stadnik P, Joseph AP, et al. Mosaic RAS\/MAPK variants cause sporadic vascular malformations which respond to targeted therapy. J Clin Invest 2018; 128: 1496-1508.","DOI":"10.1172\/JCI98589"},{"key":"29430","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1172\/JCI98589","DOI":"10.1172\/JCI98589"},{"key":"29431","doi-asserted-by":"crossref","unstructured":"Goss JA, Konczyk DJ, Smits PJ, Kozakewich HPW, Alomari AI, Al-Ibraheemi A, et al. Intramuscular fast-flow vascular anomaly contains somatic MAP2K1 and KRAS mutations. Angiogenesis 2019; 22: 547-552.","DOI":"10.1007\/s10456-019-09678-w"},{"key":"29432","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s10456-019-09678-w","DOI":"10.1007\/s10456-019-09678-w"},{"key":"29433","doi-asserted-by":"crossref","unstructured":"Chen H, Xu B, Wang G, Guo Y, Hou K, Yu J, et al. Posterior occipital intramuscular hemangioma mimicking arteriovenous malformation: Case report. Medicine (Baltimore) 2019; 98: e14678.","DOI":"10.1097\/MD.0000000000014678"},{"key":"29434","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/MD.0000000000014678","DOI":"10.1097\/MD.0000000000014678"},{"key":"29435","doi-asserted-by":"crossref","unstructured":"Russo D, Fraitag S, Bruneau B, Stock N, Aillet S, Dupuy A, et al. Non-congenital dorsal tumefaction with rapid growth in a young child identified as an intramuscular hemangioma. JAAD Case Rep 2020; 6: 616-618.","DOI":"10.1016\/j.jdcr.2020.04.039"},{"key":"29436","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.jdcr.2020.04.039","DOI":"10.1016\/j.jdcr.2020.04.039"},{"key":"29437","doi-asserted-by":"crossref","unstructured":"Lipede C, Nikkhah D, Ashton R, Murphy G, Barnacle AM, Patel PA, et al. Management of Fibro-adipose Vascular Anomalies (FAVA) in paediatric practice. JPRAS Open 2021; 29: 71-81.","DOI":"10.1016\/j.jpra.2021.05.002"},{"key":"29438","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.jpra.2021.05.002","DOI":"10.1016\/j.jpra.2021.05.002"},{"key":"29439","doi-asserted-by":"crossref","unstructured":"Dompmartin A, Acher A, Thibon P, Tourbach S, Hermans C, Deneys V, et al. Association of localized intravascular coagulopathy with venous malformations. Arch Dermatol 2008; 144: 873-877.","DOI":"10.1001\/archderm.144.7.873"},{"key":"29440","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1001\/archderm.144.7.873","DOI":"10.1001\/archderm.144.7.873"},{"key":"29441","doi-asserted-by":"crossref","unstructured":"Colletti G, Biglioli F, Poli T, Dessy M, Cucurullo M, Petrillo M, et al. Vascular malformations of the orbit (lymphatic, venous, arteriovenous): diagnosis, management and results. J Craniomaxillofac Surg 2019; 47: 726-740.","DOI":"10.1016\/j.jcms.2018.09.009"},{"key":"29442","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.jcms.2018.09.009","DOI":"10.1016\/j.jcms.2018.09.009"},{"key":"29443","doi-asserted-by":"crossref","unstructured":"Maruani A, Tavernier E, Boccara O, Mazereeuw-Hautier J, Leducq S, Bessis D, et al. Sirolimus (rapamycin) for slow-flow malformations in children: The observational-phase randomized clinical PERFORMUS trial. JAMA Dermatol 2021; 157: 1289-1298.","DOI":"10.1001\/jamadermatol.2021.3459"},{"key":"29444","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1001\/jamadermatol.2021.3459","DOI":"10.1001\/jamadermatol.2021.3459"},{"key":"29445","doi-asserted-by":"crossref","unstructured":"Chen RJ, Vrazas JI, Penington AJ. Surgical management of intramuscular venous malformations. J Pediatr Orthop 2021; 41: e67-e73.","DOI":"10.1097\/BPO.0000000000001667"},{"key":"29446","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/BPO.0000000000001667","DOI":"10.1097\/BPO.0000000000001667"},{"key":"29447","doi-asserted-by":"crossref","unstructured":"Rabe E, Pannier F. Sclerotherapy in venous malformation. Phlebology 2013; 28: 188-191.","DOI":"10.1177\/0268355513477282"},{"key":"29448","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1177\/0268355513477282","DOI":"10.1177\/0268355513477282"},{"key":"29449","doi-asserted-by":"crossref","unstructured":"Yonehara Y, Nakatsuka T, Ichioka I, Takato T, Matsumoto S, Yamada A. Intramuscular haemangioma of the anterior chest wall. Br J Plast Surg 2000; 53: 257-259.","DOI":"10.1054\/bjps.1999.3275"},{"key":"29450","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1054\/bjps.1999.3275","DOI":"10.1054\/bjps.1999.3275"},{"key":"29451","doi-asserted-by":"crossref","unstructured":"Lescura CM, de Andrade BAB, Bezerra KT, Agostini M, Ankha MVA, de Castro F, et al. Oral intramuscular hemangioma: report of three cases. J Cutan Pathol 2019; 46: 603-608.","DOI":"10.1111\/cup.13482"},{"key":"29452","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/cup.13482","DOI":"10.1111\/cup.13482"},{"key":"29453","doi-asserted-by":"crossref","unstructured":"Lyness RW, Williams R. Intramuscular haemangioma arising in the lateral rectus extraocular muscle: a case report and review of the published work. Orbit 1986; 5: 159-167.","DOI":"10.3109\/01676838609036039"},{"key":"29454","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3109\/01676838609036039","DOI":"10.3109\/01676838609036039"},{"key":"29455","doi-asserted-by":"crossref","unstructured":"Liu AS, Mulliken JB, Zurakowski D, Fishman SJ, Greene AK. Extracranial arteriovenous malformations: natural progression and recurrence after treatment Plast Reconstr Surg 2010; 125: 1185-1194.","DOI":"10.1097\/PRS.0b013e3181d18070"},{"key":"29456","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/PRS.0b013e3181d18070","DOI":"10.1097\/PRS.0b013e3181d18070"},{"key":"29457","doi-asserted-by":"crossref","unstructured":"Nicholson CL, Flanagan S, Murati M, Boull C, McGough E, Ameduri R, et al. Successful management of an arteriovenous malformation with trametinib in a patient with capillary-malformation arteriovenous malformation syndrome and cardiac compromise. Pediatr Dermatol 2022; 39: 316-319.","DOI":"10.1111\/pde.14912"},{"key":"29458","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/pde.14912","DOI":"10.1111\/pde.14912"}],"container-title":["Acta Dermato-Venereologica"],"original-title":[],"link":[{"URL":"https:\/\/medicaljournalssweden.se\/actadv\/article\/download\/4432\/15388","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicaljournalssweden.se\/actadv\/article\/download\/4432\/15388","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T14:29:08Z","timestamp":1679322548000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicaljournalssweden.se\/actadv\/article\/view\/4432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,20]]},"references-count":56,"URL":"https:\/\/doi.org\/10.2340\/actadv.v103.4432","relation":{},"ISSN":["1651-2057","0001-5555"],"issn-type":[{"value":"1651-2057","type":"electronic"},{"value":"0001-5555","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3,20]]}}}