{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T15:43:25Z","timestamp":1787413405849,"version":"build-2736575974"},"reference-count":69,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Derm Venereol"],"abstract":"<jats:p>Methacrylate allergy is a common cause of allergic contact dermatitis, and its incidence has surged over the past decade. Consequently, the primary sensitizing agent, 2-hydroxyethyl methacrylate, was recently added to the European Baseline Series of contact allergens. This study aimed to assess the added value of testing for allergens included in the (Meth)Acrylate Series \u2013 Nails, in addition to 2-hydroxyethyl methacrylate, as well as to characterize patients who may benefit from more extensive testing. A retrospective analysis of medical records of patch-tested patients was conducted between June 2013 and July 2022. Among the 3,828 patients who underwent patch testing, 396 were tested with the (Meth)Acrylate Series \u2013 Nails; 153 (38.6%) of those patients tested positive for at least 1 acrylate. The most common hapten was 2-hydroxyethyl methacrylate (85.6%), followed by hydroxypropyl methacrylate (85.0%) and ethylene glycol dimethacrylate (80.4%). In our study, 22\/153 patients (14.4%) would have been missed if tested only for 2-hydroxyethyl methacrylate. The analysis showed that including hydroxypropyl methacrylate and ethylene glycol dimethacrylate improved detection rate to 98%, rendering the use of the entire tray unnecessary in most cases.<\/jats:p>","DOI":"10.2340\/actadv.v104.41079","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T13:38:34Z","timestamp":1731418714000},"page":"adv41079","source":"Crossref","is-referenced-by-count":2,"title":["Is the Use of the Extended (Meth)acrylate Series \u2013 Nails Justified? Characterization of Nail Acrylate Allergy in a Tertiary Medical Centre"],"prefix":"10.2340","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8354-1261","authenticated-orcid":false,"given":"Joel","family":"Dascalu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Polansky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziad","family":"Khamaysi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Avitan-Hersh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariela J.","family":"Nevet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2024,11,12]]},"reference":[{"key":"81200","doi-asserted-by":"crossref","unstructured":"Rolls S, Chowdhury MM, Cooper S, Cousen P, Flynn AM, Ghaffar SA, et al. Recommendation to include hydroxyethyl (meth)acrylate in the British baseline patch test series. Br J Dermatol 2019; 181: 811-817.","DOI":"10.1111\/bjd.17708"},{"key":"81201","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/bjd.17708","DOI":"10.1111\/bjd.17708"},{"key":"81202","doi-asserted-by":"crossref","unstructured":"Gon\u00e7alo M, Pinho A, Agner T, Andersen KE, Bruze M, Diepgen T, et al. Allergic contact dermatitis caused by nail acrylates in Europe: an EECDRG study. Contact Dermatitis 2018; 78: 254-260.","DOI":"10.1111\/cod.12942"},{"key":"81203","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/cod.12942","DOI":"10.1111\/cod.12942"},{"key":"81204","doi-asserted-by":"crossref","unstructured":"Forkel S, Schubert S, Corvin L, Heine G, Lang CC V, Oppel E, et al. Contact allergies to dental materials in patients. Br J Dermatol 2024; 190: 895-903.","DOI":"10.1093\/bjd\/ljad525"},{"key":"81205","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1093\/bjd\/ljad525","DOI":"10.1093\/bjd\/ljad525"},{"key":"81206","doi-asserted-by":"crossref","unstructured":"Raposo I, Lobo I, Amaro C, Lobo M de L, Melo H, Parente J, et al. Allergic contact dermatitis caused by (meth)acrylates in nail cosmetic products in users and nail technicians: a 5-year study. Contact Dermatitis 2017; 77: 356-359.","DOI":"10.1111\/cod.12817"},{"key":"81207","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/cod.12817","DOI":"10.1111\/cod.12817"},{"key":"81208","doi-asserted-by":"crossref","unstructured":"Gregoriou S, Tagka A, Velissariou E, Tsimpidakis A, Hatzidimitriou E, Platsidaki E, et al. The rising incidence of allergic contact dermatitis to acrylates. Dermatitis 2020; 31: 140-143.","DOI":"10.1097\/DER.0000000000000528"},{"key":"81209","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/DER.0000000000000528","DOI":"10.1097\/DER.0000000000000528"},{"key":"81210","doi-asserted-by":"crossref","unstructured":"Montgomery R, Stocks SJ, Wilkinson SM. Contact allergy resulting from the use of acrylate nails is increasing in both users and those who are occupationally exposed. Contact Dermatitis 2016; 74: 120-122.","DOI":"10.1111\/cod.12497"},{"key":"81211","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/cod.12497","DOI":"10.1111\/cod.12497"},{"key":"81212","doi-asserted-by":"crossref","unstructured":"Uter W, Wilkinson SM, Aerts O, Bauer A, Borrego L, Brans R, et al. Patch test results with the European baseline series, 2019\/20: joint European results of the ESSCA and the EBS working groups of ESCD and the GEIDAC. 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Actas Dermosifiliogr 2021; 112: 798-805.","DOI":"10.1016\/j.adengl.2021.07.013"},{"key":"81232","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.ad.2021.05.005","DOI":"10.1016\/j.ad.2021.05.005"},{"key":"81233","doi-asserted-by":"crossref","unstructured":"Gatica-Ortega ME, Pastor-Nieto MA, Gim\u00e9nez-Arnau AM, Mercader-Garc\u00eda P, Sanz-S\u00e1nchez T, Carrascosa-Carrillo JM, et al. 2-Hydroxyethyl methacrylate (2-HEMA) sensitization, a global epidemic at its peak in Spain? Contact Dermatitis 2024; 90: 507-513.","DOI":"10.1111\/cod.14520"},{"key":"81234","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/cod.14520","DOI":"10.1111\/cod.14520"},{"key":"81235","doi-asserted-by":"crossref","unstructured":"DeKoven JG, Warshaw EM, Reeder MJ, Atwater AR, Silverberg JI, Belsito DV, et al. North American Contact Dermatitis Group Patch Test Results: 2019-2020. 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