{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:52:29Z","timestamp":1787025149565,"version":"build-2736575974"},"reference-count":72,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T00:00:00Z","timestamp":1735862400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Derm Venereol"],"abstract":"<jats:p>Pregnancy-associated changes in melanocytic nevi (MN), apart from size increase on the trunk, remain a topic of debate. We conducted the first prospective study to investigate dermoscopic changes in MN comparing pregnant with non-pregnant women on all body parts using a market-approved convolutional neural network (CNN). We included 25 pregnant and 25 non-pregnant women from Basel, Switzerland, who underwent standard skin cancer screenings and whose MN &gt;\u20092 mm were digitally recorded and analysed by a CNN. Pregnant women were examined three times: in the first and third trimester and 8\u201312 weeks postpartum; non-pregnant women twice in an interval of 17\u201321 weeks. We analysed 2,799 MN. In pregnant women, diameter[p\u2009&lt;\u20090.001], area[p\u2009&lt;\u20090.001], number of colours [p\u2009=\u20090.009], shape asymmetry[p\u2009=\u20090.005] and border sharpness[p\u2009=\u20090.006] (inversely proportional value) increased while ellipseness [p\u2009&lt;\u20090.001] decreased from first trimester to postpartum. Changes occurred mainly during the third trimester to postpartum. Compared to non-pregnant women (only first to third trimester) MN on the upper extremities of pregnant women increased in area[p\u2009=\u20090.011] and diameter[p\u2009=\u20090.025] and decreased in ellipseness[p\u2009=\u20090.037]. MN on the lower extremities increased in area[p\u2009=\u20090.044] and MN on the back increased in colour asymmetry[p\u2009=\u20090.022].<\/jats:p>","DOI":"10.2340\/actadv.v105.41025","type":"journal-article","created":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T03:46:50Z","timestamp":1735876010000},"page":"adv41025","source":"Crossref","is-referenced-by-count":6,"title":["AI-assisted Total Body Dermoscopic Evaluation of Changes in Melanocytic Nevi during Pregnancy: A Prospective, Comparative Study of 2,799 Nevi"],"prefix":"10.2340","volume":"105","author":[{"given":"Jelissa K.","family":"Peter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Helfenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara E.","family":"Cerminara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia-Tatjana","family":"Maul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mara L.","family":"Zehnder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmar","family":"Jamiolkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Roider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beda","family":"M\u00fchleisen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"H\u00f6sli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander A.","family":"Navarini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara V.","family":"Maul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2025,1,3]]},"reference":[{"key":"87595","doi-asserted-by":"crossref","unstructured":"Di Brizzi EV, Pampena R, Licata G, Calabrese G, Longo C, Argenziano G. 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