{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T04:08:49Z","timestamp":1744258129793,"version":"3.40.4"},"reference-count":43,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T00:00:00Z","timestamp":1744070400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Derm Venereol"],"abstract":"<jats:p>This study examined the relationship between type 2 diabetes and late syphilis. A retrospective analysis was conducted, including 96 syphilis patients with type 2 diabetes and 122 matched non-diabetic syphilis controls. The development of late-stage syphilis and responses to initial treatment were monitored over a 2-year period. Stratified logistic regression was used to assess whether diabetes increased the risk of late syphilis. Differences in initial treatment responses between the 2 groups were evaluated using \u03c72 tests and Kaplan\u2013Meier curves. The cohort study confirmed that the serological cure rate within 12 months was significantly lower in diabetic syphilis patients. Type 2 diabetes significantly impacts the efficacy of syphilis treatment and is a risk factor for late syphilis.<\/jats:p>","DOI":"10.2340\/actadv.v105.42210","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T05:14:04Z","timestamp":1744175644000},"page":"adv42210","source":"Crossref","is-referenced-by-count":0,"title":["Type 2 Diabetes Impacts the Efficacy of Syphilis Treatment and is a Risk Factor for Late Syphilis: A Retrospective Cohort Study"],"prefix":"10.2340","volume":"105","author":[{"given":"Yijie","family":"Tang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengxiao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenwen","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiajie","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dandan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaqin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingyun","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinghui","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingqiong","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1183","published-online":{"date-parts":[[2025,4,8]]},"reference":[{"key":"106835","doi-asserted-by":"crossref","unstructured":"Elendu C, Amaechi DC, Elendu ID, Elendu TC, Amaechi EC, Usoro EU, et al. 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