{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T06:14:42Z","timestamp":1778825682309,"version":"3.51.4"},"reference-count":27,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:00:00Z","timestamp":1778803200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Derm Venereol"],"abstract":"<jats:p>Multidisciplinary care pathways may improve quality of care, yet little is known about patients\u2019 perspectives regarding multidisciplinary treatment for high-risk head and neck cutaneous squamous cell carcinoma. This study examined health-related quality of life, decisional conflict, and satisfaction with care in 78 high-risk head and neck cutaneous squamous cell carcinoma patients undergoing multidisciplinary care. Pre-treatment, patients completed a baseline questionnaire, the EuroQoL-5D-5L, and the Decisional Conflict Scale. One month post-treatment, they completed the EuroQoL-5D-5L, Basal and Squamous Cell Carcinoma Quality of Life, and EORTC IN-PATSAT32 satisfaction questionnaires. Mean generic health-related quality of life scores were 0.76 pre-treatment and 0.81 post-treatment (p\u2009=\u20090.077), with minimal impact on disease-specific health-related quality of life (mean Basal and Squamous Cell Carcinoma Quality of Life scores ranging from 0.46 to 1.05). However, 73.7% of patients expressed worries about prognosis, and 12% of patients reported concerns regarding diagnosis and treatment substantially affecting health-related quality of life. The mean Decisional Conflict Scale total score was 26.61, with 19.2% of patients exceeding the clinically relevant threshold of 37.5, indicating decision delay or uncertainty regarding implementation. Approximately one-third of patients reported a need for better decision-making support. Overall, patients reported high satisfaction with care. In conclusion, while multidisciplinary care had minimal impact on health-related quality of life and resulted in high patient satisfaction, one-third of patients required more comprehensive information and value clarification.<\/jats:p>","DOI":"10.2340\/actadv.v106.44413","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T06:03:07Z","timestamp":1778824987000},"page":"adv44413","source":"Crossref","is-referenced-by-count":0,"title":["Patient Reported Outcomes in Multidisciplinary Care for High-risk Head and Neck Cutaneous Squamous Cell Carcinoma"],"prefix":"10.2340","volume":"106","author":[{"given":"Emmy C.","family":"Cruts","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9236-0379","authenticated-orcid":false,"given":"Myrthe M.G.","family":"Moermans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patty J.","family":"Nelemans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9546-8129","authenticated-orcid":false,"given":"Lieke C.J.","family":"Van Delft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric A.","family":"Dik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2694-6059","authenticated-orcid":false,"given":"Satish F.K.","family":"Lubeek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6542-7740","authenticated-orcid":false,"given":"Nicole W.J.","family":"Kelleners-Smeets","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klara","family":"Mosterd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1183","published-online":{"date-parts":[[2026,5,15]]},"reference":[{"key":"155402","doi-asserted-by":"crossref","unstructured":"Stratigos AJ, Garbe C, Dessinioti C, Lebbe C, Bataille V, -Bastholt L, et al. European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 1. epidemiology, diagnostics and prevention. Eur J Cancer 2020; 128: 60\u201382.","DOI":"10.1016\/j.ejca.2020.01.007"},{"key":"155403","doi-asserted-by":"crossref","unstructured":"Keim U, Katalinic A, Holleczek B, Wakkee M, Garbe C, Leiter U. Incidence, mortality and trends of cutaneous squamous cell carcinoma in Germany, the Netherlands, and Scotland. Eur J Cancer 2023; 183: 60\u201368.","DOI":"10.1016\/j.ejca.2023.01.017"},{"key":"155404","doi-asserted-by":"crossref","unstructured":"Tokez S, Wakkee M, Kan W, Venables ZC, Mooyaart AL, Louwman M, et al. Cumulative incidence and disease-specific survival of metastatic cutaneous squamous cell carcinoma: a nationwide cancer registry study. J Am Acad Dermatol 2022; 86: 331\u2013338.","DOI":"10.1016\/j.jaad.2021.09.067"},{"key":"155405","doi-asserted-by":"crossref","unstructured":"Soleymani T, Brodland DG, Arzeno J, Sharon DJ, Zitelli JA. Clinical outcomes of high-risk cutaneous squamous cell carcinomas treated with Mohs surgery alone: an analysis of local recurrence, regional nodal metastases, progression-free survival, and disease-specific death. J Am Acad Dermatol 2023; 88: 109\u2013117.","DOI":"10.1016\/j.jaad.2022.06.1169"},{"key":"155406","doi-asserted-by":"crossref","unstructured":"Tschetter AJ, Campoli MR, Zitelli JA, Brodland DG. Long-term clinical outcomes of patients with invasive cutaneous squamous cell carcinoma treated with Mohs micrographic surgery: a 5-year, multicenter, prospective cohort study. J Am Acad Dermatol 2020; 82: 139\u2013148.","DOI":"10.1016\/j.jaad.2019.06.1303"},{"key":"155407","unstructured":"Califano JA. AJCC Cancer Staging Manual. 8th ed. Chapter 15: Cutaneous carcinoma of the head and neck. Chicago, IL: American Joint Committee on Cancer; 2017."},{"key":"155408","doi-asserted-by":"crossref","unstructured":"Schmults CD. High-risk cutaneous squamous cell carcinoma: a practical guide for patient management. Anticancer Res 2016; 36: 4375.","DOI":"10.1007\/978-3-662-47081-7"},{"key":"155409","doi-asserted-by":"crossref","unstructured":"Schmults CD, Karia PS, Carter JB, Han J, Qureshi AA. Factors predictive of recurrence and death from cutaneous squamous cell carcinoma: a 10-year, single-institution cohort study. JAMA Dermatol 2013; 149: 541\u2013547.","DOI":"10.1001\/jamadermatol.2013.2139"},{"key":"155410","doi-asserted-by":"crossref","unstructured":"Brantsch KD, Meisner C, Schonfisch B, Trilling B, Wehner-Caroli J, Rocken M, et al. Analysis of risk factors determining prognosis of cutaneous squamous-cell carcinoma: a prospective study. Lancet Oncol 2008; 9: 713\u2013720.","DOI":"10.1016\/S1470-2045(08)70178-5"},{"key":"155411","doi-asserted-by":"crossref","unstructured":"Venables ZC, Autier P, Nijsten T, Wong KF, Langan SM, Rous B, et al. Nationwide incidence of metastatic cutaneous squamous cell carcinoma in England. JAMA Dermatol 2019; 155: 298\u2013306.","DOI":"10.1001\/jamadermatol.2018.4219"},{"key":"155412","doi-asserted-by":"crossref","unstructured":"Brougham ND, Dennett ER, Cameron R, Tan ST. The incidence of metastasis from cutaneous squamous cell carcinoma and the impact of its risk factors. J Surg Oncol 2012; 106: 811\u2013815.","DOI":"10.1002\/jso.23155"},{"key":"155413","doi-asserted-by":"crossref","unstructured":"Stratigos AJ, Garbe C, Dessinioti C, Lebbe C, van Akkooi A, Bataille V, et al. European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma. Part 1: Diagnostics and prevention \u2013 Update 2023. Eur J Cancer 2023; 193: 113251.","DOI":"10.1016\/j.ejca.2023.113251"},{"key":"155414","doi-asserted-by":"crossref","unstructured":"Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. 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Decisional conflict in patients with head and neck cancer. JAMA Otolaryngol Head Neck Surg 2023; 149: 160\u2013167.","DOI":"10.1001\/jamaoto.2022.4269"},{"key":"155426","doi-asserted-by":"crossref","unstructured":"van Delft LCJ, Essers BAB, Nelemans PJ, Mosterd K, van Winden MEC, Romaen IFL, et al. Effectiveness of a patient decision aid for patients with superficial basal cell carcinoma: a pre- and post-implementation study. Patient Educ Couns 2023; 115: 107907.","DOI":"10.1016\/j.pec.2023.107907"},{"key":"155427","doi-asserted-by":"crossref","unstructured":"van Winden MEC, Klosters FM, Hamaker M, Olde Rikkert MG, van de Kerkhof PCM, de Jong E, et al. Optimizing shared decision making in older adults with basal cell carcinoma: experiences from a specialized outpatient clinic. Br J Dermatol 2022; 186: 589\u2013591.","DOI":"10.1111\/bjd.20833"},{"key":"155428","doi-asserted-by":"crossref","unstructured":"de Rooij BH, Ezendam NPM, Mols F, Vissers PAJ, Thong MSY, Vlooswijk CCP, et al. 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