{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T11:41:01Z","timestamp":1776858061280,"version":"3.51.2"},"reference-count":34,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AO"],"abstract":"<jats:p>Background and purpose: Routine collection of patient-reported outcome measures (PROMs) may provide valuable real-world data on quality of life (QoL) and treatment tolerability, complementing clinical outcomes. This study evaluated the feasibility of launching a semi-automated, department-wide PROM collection program at a large tertiary radiotherapy centre.Patients and methods: Patients \u2265 18 years referred for radiotherapy were invited to participate. Exclusion criteria were inability to provide informed consent, severe cognitive conditions, or language barriers. PROMs were collected using a web-based application (\u201cBl\u00e5 Appen\u201d) at baseline, end-of-treatment, and follow-up intervals, using the EORTC QLQ-C30 questionnaire (Version 3). Results: During the study period (January 2022 to April 2025), 12,472 patients underwent treatment in the department. A total of 4,764 provided informed consent for study participation, where 3,699 (77.6%) remained after exclusion due to data loss or data inconsistency. Among these, 3,056 patients (82.6%) provided at least one usable PROM questionnaire at baseline. Participants were younger (median age 69 years vs. 71 years). Overall, global health status was relatively high at baseline and remained stable or slightly improved at one-year follow-up. To further investigate clinically significant changes in QoL over time, we evaluated the proportion of patients in each diagnostic category who experienced a change of &gt; 10 points in selected QLQ-C30 scales between baseline and follow-up. Breast cancer patients had the highest rates of meaningful improvement and the lowest rates of major deterioration. In contrast, prostate cancer patients were more prone to significant declines in QoL scales over time. Interpretation: This prospective study demonstrates that department-wide collection of PROM is feasible. Using a digital platform, we achieved a high initial response rate and successfully engaged patients across a broad range of cancers. The routine PROM collection provided valuable insights into patients\u2019 quality of life and symptom burden during and after treatment.<\/jats:p>","DOI":"10.2340\/ao.v65.45546","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T10:52:03Z","timestamp":1776855123000},"page":"326-332","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility of patient-reported outcomes collection in clinical routine at a radiotherapy department"],"prefix":"10.2340","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2742-0887","authenticated-orcid":false,"given":"Ingrid","family":"Fagerstr\u00f6m Kristensen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anton","family":"Linn\u00e9r","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Nilsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktor","family":"Rogowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5988-8994","authenticated-orcid":false,"given":"Per","family":"Munck af Rosensch\u00f6ld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4509-6707","authenticated-orcid":false,"given":"Mats","family":"Jerkeman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1183","published-online":{"date-parts":[[2026,4,22]]},"reference":[{"key":"151766","doi-asserted-by":"crossref","unstructured":"Basch E, Deal AM, Kris MG, Scher HI, Hudis CA, Sabbatini P, et al. 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JCO Oncol Pract. 2022;18(12):e1918\u201326.","DOI":"10.1200\/OP.22.00180"},{"key":"151774","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1200\/OP.22.00180","DOI":"10.1200\/OP.22.00180"},{"key":"151775","doi-asserted-by":"crossref","unstructured":"Franzoi MA, Ferreira AR, Lemaire A, Rodriguez J, Grosjean J, Ribeiro JM, et al. Implementation of a remote symptom monitoring pathway in oncology care: analysis of real-world experience across 33 cancer centres in France and Belgium. Lancet Reg Health Eur. 2024;44:101005.","DOI":"10.1016\/j.lanepe.2024.101005"},{"key":"151776","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.lanepe.2024.101005","DOI":"10.1016\/j.lanepe.2024.101005"},{"key":"151777","doi-asserted-by":"crossref","unstructured":"Kurosawa S, Koike K, Arai T, Yoshida S, Ito M, Kuriyama Y, et al. Feasibility and usefulness of symptom monitoring with electronic patient-reported outcomes: an experience at single-center outpatient oncology clinic. Support Care Cancer. 2024;33(1):3.","DOI":"10.1007\/s00520-024-09062-5"},{"key":"151778","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s00520-024-09062-5","DOI":"10.1007\/s00520-024-09062-5"},{"key":"151779","doi-asserted-by":"crossref","unstructured":"Patt D, Wilfong L, Hudson KE, Patel A, Books H, Pearson B, et al. Implementation of electronic patient-reported outcomes for symptom monitoring in a large multisite community oncology practice: dancing the texas two-step through a pandemic. 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Fatigue, health-related quality-of-life and metabolic changes in men treated with enzalutamide or abiraterone acetate plus prednisone for metastatic castration-resistant prostate cancer: a randomised clinical trial (HEAT). Eur J Cancer. 2022;171:75\u201384.","DOI":"10.1016\/j.ejca.2022.04.034"},{"key":"151791","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.ejca.2022.04.034","DOI":"10.1016\/j.ejca.2022.04.034"},{"key":"151792","doi-asserted-by":"crossref","unstructured":"Bade BC, Zhao J, Li F, Tanoue L, Lazowski H, Alfano CM, et al. Trends and predictors of Quality of Life in lung cancer survivors. Lung Cancer. 2024;191:107793.","DOI":"10.1016\/j.lungcan.2024.107793"},{"key":"151793","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.lungcan.2024.107793","DOI":"10.1016\/j.lungcan.2024.107793"},{"key":"151794","doi-asserted-by":"crossref","unstructured":"Trejo MJ, Bell ML, Dhillon HM, Vardy JL. 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