{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T19:39:56Z","timestamp":1778269196295,"version":"3.51.4"},"reference-count":25,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BIiD"],"abstract":"<jats:p>Objective: The aim of the present study was to evaluate the antimicrobial activity of resin-modified glass ionomer cements (RMGICs) supplemented with red propolis ethanolic extract (RPEE) against Streptococcus mutans cultures.\nMaterials and methods: Four RMGICs (Gold Label, Ionolux, Vitro Fill, and Riva) were used with the addition of RPEE at concentrations of 11% and 20%. For the control groups, the cements were manipulated and light-cured according to the manufacturers\u2019 instructions. S. mutans strains from stock cultures were grown in brain heart infusion (BHI) broth. Cement samples were placed in direct contact with the microorganism for 48 h in a bacteriological incubator. After this period, the diameters of the inhibition zones were measured using a digital caliper.\nResults: Data analysis showed a significant increase in the size of the inhibition zones for Gold Label and Vitro Fill RMGICs in the groups with 11% RPEE, compared to their respective controls. When comparing different cement brands containing 11% RPEE, Gold Label and Vitro Fill exhibited significantly larger inhibition zones than Ionolux.\nConclusion: The addition of 11% RPEE was shown to enhance the antimicrobial activity of two of the four tested RMGICs, with Gold Label and Vitro Fill demonstrating the greatest antimicrobial potential following supplementation with RPEE.<\/jats:p>","DOI":"10.2340\/biid.v12.44895","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T08:49:01Z","timestamp":1761727741000},"page":"150-154","source":"Crossref","is-referenced-by-count":1,"title":["Antimicrobial efficacy of light-cured glass ionomer cements incorporating red propolis extract"],"prefix":"10.2340","volume":"12","author":[{"given":"Maria Helena Nunes","family":"Borges","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thays Maria de Oliveira","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Henrique","family":"Sette-de-Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayara Abreu","family":"Pinheiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bas\u00edlio Rodrigues","family":"Vieira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00eaisa Aiane de Morais","family":"Sampaio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1183","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"131517","doi-asserted-by":"crossref","unstructured":"Sidhu SK, Nicholson JW. 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J Contemp Dent Pract. 2016;17(4):331\u20136. http:\/\/doi.org\/10.5005\/jp-journals-10024-1850","DOI":"10.5005\/jp-journals-10024-1850"},{"key":"131523","doi-asserted-by":"crossref","unstructured":"Hatunoglu E, Ozturk F, Bilenler T, Aksakalli S, Simsek N. Antibacterial and mechanical properties of propolis added to glass ionomer cement. Angle Orthod. 2014;84:368\u201373. http:\/\/doi.org\/10.2319\/020413\u2011101.1","DOI":"10.2319\/020413-101.1"},{"key":"131524","doi-asserted-by":"crossref","unstructured":"Marti LM, Mata M, Ferraz-Santos B, Azevedo ER, Giro EM, Zuanon AC. Addition of chlorhexidine gluconate to a glass ionomer cement: a study on mechanical, physical and antibacterial properties. Braz Dent J. 2014;25:33\u20137. http:\/\/doi.org\/10.1590\/0103-6440201302328","DOI":"10.1590\/0103-6440201302328"},{"key":"131525","doi-asserted-by":"crossref","unstructured":"De Morais Sampaio GA, Lacerda-Santos R, Cavalcanti YW, Vieira GHA, Nonaka CFW, Alves PM. Antimicrobial properties, mechanics, and fluoride release of ionomeric cements modified by red propolis. Angle Orthod. 2021;91(4):522\u20137. http:\/\/doi.org\/10.2319\/083120\u2011759.1","DOI":"10.2319\/083120-759.1"},{"key":"131526","doi-asserted-by":"crossref","unstructured":"Akao Y, Maruyama H, Matsumoto K, et al. Cell growth inhibitory effect of cinnamic acid derivatives from propolis on human tumor cell lines. Biol Pharm Bull. 2003;26(7):1057\u20139. http:\/\/doi.org\/ 10.1248\/bpb.26.1057","DOI":"10.1248\/bpb.26.1057"},{"key":"131527","doi-asserted-by":"crossref","unstructured":"Ferreira FB, Torres SA, Rosa OP, et al. Antimicrobial effect of propolis and other substances against selected endodontic pathogens. 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