{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T07:33:10Z","timestamp":1789543990533,"version":"build-2803163510"},"reference-count":32,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BIiD"],"abstract":"<jats:p>Objective: Given the limited evidence on the effect of effervescent multivitamin solutions on the color stability of contemporary resin composites, this study aimed to evaluate and compare their impact under simulated daily use conditions.\nMaterials and Methods: Five resin composites (Charisma Smart, Filtek One Bulk Fill, Omnichroma, Ruby Comp Nano, Ruby Flow) were tested using 200 disk-shaped specimens divided into a distilled water control group and three experimental groups: Sambucol Plus (SMB), Supradyn Effervescent Tablet (SPR), and Youplus Vitamin C, Zinc, Propolis (YPL) effervescent tablets. Each tablet was dissolved in 200 mL distilled water; specimens were immersed twice daily for 2 min over 28 days. Color measurements (CIELAB, \u0394E00, Whiteness Index) were taken at baseline, 14 and 28 days using a spectrophotometer. Data were analyzed using repeated-measures analysis of variance (ANOVA); Welch ANOVA and Games\u2013Howell post-hoc tests were used where appropriate, with the significance level set at p &lt; 0.05.\nResults: Resin composite and immersion solution had significant effects on color change (p &lt; 0.001), while time interval was also significant (p = 0.009). After 28 days, the highest discoloration was observed in Filtek One Bulk Fill immersed in Youplus (\u0394E\u2080\u2080 = 9.93 \u00b1 0.73), followed by Omnichroma immersed in Supradyn (\u0394E\u2080\u2080 = 5.63 \u00b1 0.83). Several groups exceeded the clinical acceptability threshold (\u0394E\u2080\u2080 = 1.8), particularly Filtek One Bulk Fill and Omnichroma exposed to Youplus and Supradyn. Significant time \u00d7 composite, time \u00d7 solution, and time \u00d7 composite \u00d7 solution interactions were detected (all p &lt; 0.001). The Whiteness Index also showed significant changes over time, particularly in the Youplus- and Supradyn-exposed groups.\nConclusion: Within the limitations of this in vitro study, multivitamin effervescent tablets adversely affected the color stability of some resin composites, particularly Filtek One Bulk Fill and Omnichroma. Further clinically relevant and in vivo studies are needed to determine the significance of these findings under oral conditions.<\/jats:p>","DOI":"10.2340\/biid.v13.46591","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T10:02:50Z","timestamp":1785837770000},"page":"621-630","source":"Crossref","is-referenced-by-count":1,"title":["Effect of effervescent multivitamin solutions on the color stability of contemporary resin composites: an in vitro study"],"prefix":"10.2340","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9616-1460","authenticated-orcid":false,"given":"Yeliz Hayriye Yaz\u0131c\u0131o\u011flu","family":"Pirpir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6828-5063","authenticated-orcid":false,"given":"Osman Tolga","family":"Harorl\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2026,8,4]]},"reference":[{"key":"164697","doi-asserted-by":"crossref","unstructured":"Maghaireh GA, Alzraikat H, Taha NA. 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Color stability of microhybrid and nanofilled composite resins: effect of surface sealant agents containing different filler content. J Contemp Dent Pract. 2019\u037e20:1045\u201350.","DOI":"10.5005\/jp-journals-10024-2636"},{"key":"164705","doi-asserted-by":"crossref","unstructured":"Hashir M, Ravishankar P, Dhanapal S, PradeepKumar AR. Color match of composite resin and remaining tooth structure over a period of 28 days using spectrophotometer-a randomized clinical trial. Oper Dent. 2021\u037e46:609\u201320.","DOI":"10.2341\/20-222-C"},{"key":"164706","doi-asserted-by":"crossref","unstructured":"Wegehaupt FJ, Lunghi N, Hogger VMG, Attin T. Erosive potential of vitamin and vitamin+mineral effervescent tablets. Swiss Dent J. 2016;126(5):457\u201365.","DOI":"10.61872\/sdj-2016-05-01"},{"key":"164707","doi-asserted-by":"crossref","unstructured":"Guler EBG, Bayrak GD, Unsal M, Kuvvetli SS. Effect of pediatric multivitamin syrups and effervescent tablets on the surface microhardness and roughness of restorative materials: an in vitro study. J Dent Sci. 2021\u037e16:311\u20137.","DOI":"10.1016\/j.jds.2020.03.017"},{"key":"164708","doi-asserted-by":"crossref","unstructured":"Kr\u00fcger J, Maletz R, Ottl P, Warkentin M. In-vitro aging behavior of dental composites considering the influence of filler content, storage media and incubation time. PLoS One. 2018\u037e13:e0195160.","DOI":"10.1371\/journal.pone.0195160"},{"key":"164709","doi-asserted-by":"crossref","unstructured":"Guo J, Bing Z, Yang J, Tsoi JKH, Wang Y. Effect of roughness and acidic medium on wear behavior of dental resin composite. BMC Oral Health. 2022\u037e22:470.","DOI":"10.1186\/s12903-022-02516-4"},{"key":"164710","doi-asserted-by":"crossref","unstructured":"Ayd\u0131n N, Top\u00e7u FT, Karao\u011flano\u011flu S, Oktay EA, Erdemir U. Effect of finishing and polishing systems on the surface roughness and color change of composite resins. J Clin Exp Dent. 2021\u037e13:e446\u201354.","DOI":"10.4317\/jced.58011"},{"key":"164711","doi-asserted-by":"crossref","unstructured":"Kang S, Cho BH. Effects of an acidic environment on the strength and chemical changes of resin-based composites. Oper Dent. 2023\u037e48:E81\u201394.","DOI":"10.2341\/22-031-L"},{"key":"164712","doi-asserted-by":"crossref","unstructured":"Alqarni AS, AlGomaiah MA, AlEdaili EA, Algamaiah H. Assessment of erosive effect of various beverages on esthetic restorative materials used in primary teeth: an in vitro study. J Contemp Dent Pract. 2023\u037e24:473\u20136.","DOI":"10.5005\/jp-journals-10024-3488"},{"key":"164713","doi-asserted-by":"crossref","unstructured":"Igiel C, Lehmann KM, Ghinea R, Weyhrauch M, Hangx Y, Scheller H, et al. Reliability of visual and instrumental color matching. 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