{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T11:59:48Z","timestamp":1770983988459,"version":"3.50.1"},"reference-count":0,"publisher":"Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T00:00:00Z","timestamp":1667520000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JRM"],"abstract":"<jats:p>Objective: To investigate training at different intensity levels on cardiac function, exercise capacity, and health-related quality of life in patients with chronic heart failure.Methods: This prospective cohort study enrolled patients with chronic heart failure at Beijing Rehabilitation Hospital, Beijing, China from January 2018 to January 2020. Participants received conventional therapy (non-exercise group) or therapy plus cycle ergometer exercises at an intensity of 80% anaerobic threshold (EA group) and \u039450% power above anaerobic threshold (EB group) for 12 weeks. The primary outcome was peak oxygen uptake.Results: Forty-five patients (15\/group) completed the study without serious complications. Exercise training at an intensity of \u039450% power above anaerobic threshold had better effects on exercise capacity than exercise at an intensity of 80% anaerobic threshold, as shown by a greater improvement in peak oxygen uptake (20.3 \u00b1 4.1 vs 16.8 \u00b1 3.2 mL\/min\/kg), peak O2 pulse (12.5 \u00b1 2.3 vs 10.1 \u00b1 2.1 mL\/beat), and peak workload (123.1 \u00b1 26.9 vs 102.8 \u00b1 29.5 W) in patients with chronic heart failure (all p &lt; 0.001). Exercise improved the 6-min walk test distance (control: 394.0 \u00b1 74.1; EA: 481.4 \u00b1 89.4; EB: 508.9 \u00b1 92.5 m; p &lt; 0.001) and health-related quality of life (control: 40.7 \u00b1 12.3; EA: 16.2 \u00b1 8.6; EB: 11.5 \u00b1 6.4; p &lt; 0.001).Conclusion: Compared with an intensity of 80% anaerobic threshold, exercise training at an intensity of \u0394 50% power above anaerobic threshold was safe and had better effects on cardiac function, exercise capacity, and health-related quality of life.\nLAY ABSTRACTThe aim of this study was to investigate training at different intensity levels on cardiac function, exercise capacity, and health-related quality of life in patients with chronic heart failure. Exercise training at an intensity of \u0394 50% power above anaerobic threshold (mild anaerobic exercise) had better effects on exercise capacity than non-exercise and intensity of 80% anaerobic threshold (aerobic exercise). In addition, exercise resulted in improved health-related quality of life compared with non-exercise. Therefore, the benefit may be greater if the exercise intensity is increased appropriately under safe conditions.<\/jats:p>","DOI":"10.2340\/jrm.v54.1023","type":"journal-article","created":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T12:45:47Z","timestamp":1666269947000},"page":"jrm00347","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Exercise Training at Different Intensity Levels on Cardiac Function and Exercise Capacity in Patients with Chronic Heart Failure: A Prospective Cohort Study"],"prefix":"10.2340","volume":"54","author":[{"given":"Zhenying","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lizhong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianing","family":"Xi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojing","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingguo","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1183","published-online":{"date-parts":[[2022,11,4]]},"container-title":["Journal of Rehabilitation Medicine"],"original-title":[],"link":[{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/download\/1023\/8098","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/download\/1023\/8098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T13:30:30Z","timestamp":1683811830000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/view\/1023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,4]]},"references-count":0,"URL":"https:\/\/doi.org\/10.2340\/jrm.v54.1023","relation":{},"ISSN":["1651-2081"],"issn-type":[{"value":"1651-2081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,4]]}}}