{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:49:21Z","timestamp":1787532561420,"version":"build-2736575974"},"reference-count":71,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100016670","name":"Region \u00d6sterg\u00f6tland","doi-asserted-by":"publisher","award":["R\u00d6-926131"],"award-info":[{"award-number":["R\u00d6-926131"]}],"id":[{"id":"10.13039\/100016670","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JRM"],"abstract":"<jats:p>Objective: Chronic pain is a common manifestation of Ehlers-Danlos syndrome and hypermobility spectrum disorders; thus it is often suggested that patients undergo generic interdisciplinary pain rehabilitation, despite there being little evidence to support this decision. The aim of this study is to examine the effectiveness of standard rehabilitation programmes for chronic pain on patients with Ehlers-Danlos syndrome and hypermobility spectrum disorders, compared with patients with other chronic pain disorders.\nSubjects: Data, collected between 2008 and 2016, were extracted from a Swedish national registry. The patient data comprised of 406 cases with Ehlers-Danlos syndrome or hypermobility spectrum disorders, 784 cases with a whiplash-related diagnosis, 3713 cases with diagnoses relating to spinal pain, and 2880 cases of fibromyalgia.\nMethods: The differences between groups on key outcome measures from pre- to 1-year follow-up after interdisciplinary pain rehabilitation were analysed using linear mixed effects models. Sensitivity analysis in the form of pattern-mixture modelling was conducted to discern the impact of missing data. \nResults: No significant differences were found in improvements from pre- to 1-year follow-up for patients with Ehlers-Danlos syndrome or hypermobility spectrum disorder compared with other diagnostic groups regarding measures of health-related quality of life, mental health, or fatigue. At follow-up, differences in pain interference (d\u2009=\u2009\u20130.34 (95% confidence interval [95% CI] \u20130.5 to \u20130.18)), average pain (d\u2009=\u20090.22 (95% CI 0.11\u20130.62)) and physical functioning (d\u2009=\u20092.19 (95% CI 1.61\u20132.77)) were detected for the group with spinal-related diagnoses in relation to those with EDS\/HSD, largely due to pre-treatment group differences. Sensitivity analysis found little evidence for missing data influencing the results.\nConclusion: This study suggests that patients with Ehlers-Danlos syndrome\/hypermobility spectrum disorders may benefit from inclusion in an interdisciplinary pain rehabilitation programme.<\/jats:p>","DOI":"10.2340\/jrm.v56.12431","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T10:44:47Z","timestamp":1707302687000},"page":"jrm12431","source":"Crossref","is-referenced-by-count":2,"title":["Interdisciplinary pain rehabilitation for patients with Ehlers-Danlos syndrome and hypermobility spectrum disorders"],"prefix":"10.2340","volume":"56","author":[{"given":"Peter","family":"Molander","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmed","family":"Novo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c5sa","family":"Ringqvist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"H\u00e5llstam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Hesser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"L\u00f6fgren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britt-Marie","family":"St\u00e5lnacke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Gerdle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2024,2,7]]},"reference":[{"key":"48493","doi-asserted-by":"crossref","unstructured":"Kinge JM, Knudsen AK, Skirbekk V, Vollset SE. Musculoskeletal disorders in Norway: prevalence of chronicity and use of primary and specialist health care services. BMC Musculoskelet Disord 2015; 16: 75.","DOI":"10.1186\/s12891-015-0536-z"},{"key":"48494","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1186\/s12891-015-0536-z","DOI":"10.1186\/s12891-015-0536-z"},{"key":"48495","doi-asserted-by":"crossref","unstructured":"Malfait F, Francomano C, Byers P, Belmont J, Berglund B, Black J, et al. The 2017 international classification of the Ehlers\u2013Danlos syndromes. Am J Med Genet C Semin Med Genet 2017; 175: 8\u201326.","DOI":"10.1002\/ajmg.c.31552"},{"key":"48496","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1002\/ajmg.c.31552","DOI":"10.1002\/ajmg.c.31552"},{"key":"48497","unstructured":"Syx D, Wandele ID, Rombaut L, Malfait F. Hypermobility, the Ehlers-Danlos syndromes and chronic pain. Clin Exp Rheumatol 2017; 35: 116\u2013122."},{"key":"48498","doi-asserted-by":"crossref","unstructured":"Castori M, Tinkle B, Levy H, Grahame R, Malfait F, Hakim A. A framework for the classification of joint hypermobility and related conditions. Am J Med Genet C Semin Med Genet 2017; 175: 148\u2013157.","DOI":"10.1002\/ajmg.c.31539"},{"key":"48499","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1002\/ajmg.c.31539","DOI":"10.1002\/ajmg.c.31539"},{"key":"48500","doi-asserted-by":"crossref","unstructured":"Rombaut L, Malfait F, De Paepe A, Rimbaut S, Verbruggen G, De Wandele I, et al. Impairment and impact of pain in female patients with Ehlers-Danlos syndrome: a comparative study with fibromyalgia and rheumatoid arthritis. Arthritis Rheum 2011; 63: 1979\u20131987.","DOI":"10.1002\/art.30337"},{"key":"48501","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1002\/art.30337","DOI":"10.1002\/art.30337"},{"key":"48502","doi-asserted-by":"crossref","unstructured":"Castori M. Pain in Ehlers-Danlos syndromes: manifestations, therapeutic strategies and future perspectives. Expert Opin Orphan Drugs 2016; 4: 1145\u20131158.","DOI":"10.1080\/21678707.2016.1238302"},{"key":"48503","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1080\/21678707.2016.1238302","DOI":"10.1080\/21678707.2016.1238302"},{"key":"48504","doi-asserted-by":"crossref","unstructured":"Baets SD, Cruyt E, Calders P, Dewandele I, Malfait F, Vanderstraeten G, et al. Societal participation in ehlers-danlos syndromes and hypermobility spectrum disorder, compared to fibromyalgia and healthy controls. PLOS One 2022; 17: e0269608.","DOI":"10.1371\/journal.pone.0269608"},{"key":"48505","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1371\/journal.pone.0269608","DOI":"10.1371\/journal.pone.0269608"},{"key":"48506","doi-asserted-by":"crossref","unstructured":"Molander P, Novo M, H\u00e5llstam A, L\u00f6fgren M, St\u00e5lnacke B-M, Gerdle B. Ehlers\u2013Danlos syndrome and hypermobility syndrome compared with other common chronic pain diagnoses \u2013 a study from the Swedish Quality Registry for Pain Rehabilitation. J Clin Med 2020; 9: 2143.","DOI":"10.3390\/jcm9072143"},{"key":"48507","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3390\/jcm9072143","DOI":"10.3390\/jcm9072143"},{"key":"48508","doi-asserted-by":"crossref","unstructured":"Ringqvist \u00c5, Dragioti E, Bj\u00f6rk M, Larsson B, Gerdle B. Moderate and stable pain reductions as a result of interdisciplinary pain rehabilitation-a cohort study from the Swedish Quality Registry for Pain Rehabilitation (SQRP). J Clin Med 2019; 8: 905.","DOI":"10.3390\/jcm8060905"},{"key":"48509","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3390\/jcm8060905","DOI":"10.3390\/jcm8060905"},{"key":"48510","doi-asserted-by":"crossref","unstructured":"Cohen SP, Vase L, Hooten WM. Chronic pain: an update on burden, best practices, and new advances. The Lancet 2021; 397: 2082\u20132097.","DOI":"10.1016\/S0140-6736(21)00393-7"},{"key":"48511","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/S0140-6736(21)00393-7","DOI":"10.1016\/S0140-6736(21)00393-7"},{"key":"48512","doi-asserted-by":"crossref","unstructured":"Gatchel RJ, Peng YB, Peters ML, Fuchs PN, Turk DC. The biopsychosocial approach to chronic pain: Scientific advances and future directions. Psychol Bull 2007; 133: 581\u2013624.","DOI":"10.1037\/0033-2909.133.4.581"},{"key":"48513","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1037\/0033-2909.133.4.581","DOI":"10.1037\/0033-2909.133.4.581"},{"key":"48514","doi-asserted-by":"crossref","unstructured":"Gerdle B, Fischer MR, Ringqvist \u00c5. Interdisciplinary Pain Rehabilitation Programs: Evidence and Clinical Real-World Results. IntechOpen; 2022 [cited 2022 Jun 30].","DOI":"10.5772\/intechopen.102411"},{"key":"48515","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.5772\/intechopen.102411","DOI":"10.5772\/intechopen.102411"},{"key":"48516","doi-asserted-by":"crossref","unstructured":"Rivano Fischer M, Schults M-L, St\u00e5lnacke B-M, Ekholm J, Persson EB, L\u00f6fgren M. Variability in patient characteristics and service provision of interdisciplinary pain rehabilitation: a study using the Swedish national quality registry for pain rehabilitation. J Rehabil Med 2020; 52: jrm00128.","DOI":"10.2340\/16501977-2765"},{"key":"48517","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.2340\/16501977-2765","DOI":"10.2340\/16501977-2765"},{"key":"48518","doi-asserted-by":"crossref","unstructured":"Waterschoot FPC, Dijkstra PU, Hollak N, de Vries HJ, Geertzen JHB, Reneman MF. Dose or content? Effectiveness of pain rehabilitation programs for patients with chronic low back pain: a systematic review. Pain 2014; 155: 179\u2013189.","DOI":"10.1016\/j.pain.2013.10.006"},{"key":"48519","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.pain.2013.10.006","DOI":"10.1016\/j.pain.2013.10.006"},{"key":"48520","doi-asserted-by":"crossref","unstructured":"Kamper SJ, Apeldoorn AT, Chiarotto A, Smeets RJEM, Ostelo RWJG, Guzman J, et al. Multidisciplinary biopsychosocial rehabilitation for chronic low back pain: Cochrane systematic review and meta-analysis. BMJ 2015; 350: h444.","DOI":"10.1136\/bmj.h444"},{"key":"48521","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1136\/bmj.h444","DOI":"10.1136\/bmj.h444"},{"key":"48522","unstructured":"Swedish Council on Health Technology Assessment. Rehabilitation for chronic pain: a systematic literature review. Stockholm: SBU, Swedish Agency for Health Technology Assessment and Assessment of Social Services; 2010. Report no.: 177\u20131+2."},{"key":"48523","doi-asserted-by":"crossref","unstructured":"Corrado B, Ciardi G. Hypermobile Ehlers-Danlos syndrome and rehabilitation: taking stock of evidence based medicine: a systematic review of the literature. J Phys Ther Sci 2018; 30: 843\u2013847.","DOI":"10.1589\/jpts.30.847"},{"key":"48524","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1589\/jpts.30.847","DOI":"10.1589\/jpts.30.847"},{"key":"48525","doi-asserted-by":"crossref","unstructured":"Palmer S, Davey I, Oliver L, Preece A, Sowerby L, House S. The effectiveness of conservative interventions for the management of syndromic hypermobility: a systematic literature review. Clin Rheumatol 2021; 40: 1113\u20131129.","DOI":"10.1007\/s10067-020-05284-0"},{"key":"48526","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s10067-020-05284-0","DOI":"10.1007\/s10067-020-05284-0"},{"key":"48527","doi-asserted-by":"crossref","unstructured":"Baeza-Velasco C, Bulbena A, Polanco-Carrasco R, Jaussaud R. Cognitive, emotional, and behavioral considerations for chronic pain management in the Ehlers-Danlos syndrome hypermobility-type: a narrative review. Disabil Rehabil 2019; 41: 1110\u20131118.","DOI":"10.1080\/09638288.2017.1419294"},{"key":"48528","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1080\/09638288.2017.1419294","DOI":"10.1080\/09638288.2017.1419294"},{"key":"48529","doi-asserted-by":"crossref","unstructured":"Chopra P, Tinkle B, Hamonet C, Brock I, Gompel A, Bulbena A, et al. Pain management in the Ehlers-Danlos syndromes. Am J Med Genet C Semin Med Genet 2017; 175: 212\u2013219.","DOI":"10.1002\/ajmg.c.31554"},{"key":"48530","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1002\/ajmg.c.31554","DOI":"10.1002\/ajmg.c.31554"},{"key":"48531","doi-asserted-by":"crossref","unstructured":"Bathen T, H\u00e5ngmann AB, Hoff M, \u00d8in\u00e6s Andersen L, Rand-Hendriksen S. Multidisciplinary treatment of disability in Ehlers-Danlos syndrome hypermobility type\/hypermobility syndrome: a pilot study using a combination of physical and cognitive-behavioral therapy on 12 women. Am J Med Genet A 2013; 161A: 3005\u20133011.","DOI":"10.1002\/ajmg.a.36060"},{"key":"48532","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1002\/ajmg.a.36060","DOI":"10.1002\/ajmg.a.36060"},{"key":"48533","doi-asserted-by":"crossref","unstructured":"Hakimi A, Bergoin C, Mucci P. Immediate and 6-week after effects of a rehabilitation program for Ehlers\u2013Danlos syndrome hypermobile type patients: a retrospective study. Am J Med Genet A 2020; 182: 2263\u20132271.","DOI":"10.1002\/ajmg.a.61772"},{"key":"48534","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1002\/ajmg.a.61772","DOI":"10.1002\/ajmg.a.61772"},{"key":"48535","doi-asserted-by":"crossref","unstructured":"Rahman A, Daniel C, Grahame R. Efficacy of an out-patient pain management programme for people with joint hypermobility syndrome. Clin Rheumatol 2014; 33: 1665\u20131669.","DOI":"10.1007\/s10067-014-2539-9"},{"key":"48536","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s10067-014-2539-9","DOI":"10.1007\/s10067-014-2539-9"},{"key":"48537","doi-asserted-by":"crossref","unstructured":"Dworkin RH, Turk DC, Farrar JT, Haythornthwaite JA, Jensen MP, Katz NP, et al. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations: Pain 2005; 113: 9\u201319.","DOI":"10.1016\/j.pain.2004.09.012"},{"key":"48538","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.pain.2004.09.012","DOI":"10.1016\/j.pain.2004.09.012"},{"key":"48539","doi-asserted-by":"crossref","unstructured":"Kaiser U, Kopkow C, Deckert S, Neustadt K, Jacobi L, Cameron P, et al. Developing a core outcome domain set to assessing effectiveness of interdisciplinary multimodal pain therapy: the VAPAIN consensus statement on core outcome domains. Pain 2018; 159: 673\u2013683.","DOI":"10.1097\/j.pain.0000000000001129"},{"key":"48540","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/j.pain.0000000000001129","DOI":"10.1097\/j.pain.0000000000001129"},{"key":"48541","doi-asserted-by":"crossref","unstructured":"Haefeli M, Elfering A. Pain assessment. Eur Spine J 2006; 15: S17\u2013S24.","DOI":"10.1007\/s00586-005-1044-x"},{"key":"48542","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s00586-005-1044-x","DOI":"10.1007\/s00586-005-1044-x"},{"key":"48543","doi-asserted-by":"crossref","unstructured":"Bergstr\u00f6m G, Jensen IB, Bodin L, Linton SJ, Nygren \u00c5 L, Carlsson SG. Reliability and factor structure of the multidimensional pain inventory \u2013 Swedish language version (MPI-S). Pain 1998; 75: 101\u2013110.","DOI":"10.1016\/S0304-3959(97)00210-8"},{"key":"48544","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/S0304-3959(97)00210-8","DOI":"10.1016\/S0304-3959(97)00210-8"},{"key":"48545","doi-asserted-by":"crossref","unstructured":"Rabin R, Charro F de. EQ-SD: a measure of health status from the EuroQol Group. Ann Med 2001; 33: 337\u2013343.","DOI":"10.3109\/07853890109002087"},{"key":"48546","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3109\/07853890109002087","DOI":"10.3109\/07853890109002087"},{"key":"48547","doi-asserted-by":"crossref","unstructured":"Sullivan M, Karlsson J, Ware JE. The Swedish SF-36 Health Survey-I. Evaluation of data quality, scaling assumptions, reliability and construct validity across general populations in Sweden. Soc Sci Med 1995; 41: 1349\u20131358.","DOI":"10.1016\/0277-9536(95)00125-Q"},{"key":"48548","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/0277-9536(95)00125-Q","DOI":"10.1016\/0277-9536(95)00125-Q"},{"key":"48549","unstructured":"Hedeker D, Gibbons RD. Longitudinal data analysis. Vol. 2006. Wiley; 2006 [cited 2021 Mar 15]. Available from: https:\/\/www.wiley.com\/en-us\/Longitudinal+Data+Analysis-p-9780471420279"},{"key":"48550","doi-asserted-by":"crossref","unstructured":"Feingold A. Confidence interval estimation for standardized effect sizes in multilevel and latent growth modeling. J Consult Clin Psychol 2015; 83: 157\u2013168.","DOI":"10.1037\/a0037721"},{"key":"48551","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1037\/a0037721","DOI":"10.1037\/a0037721"},{"key":"48552","doi-asserted-by":"crossref","unstructured":"Hedeker D, Gibbons RD. Application of random-effects pattern-mixture models for missing data in longitudinal studies. Psychol Methods 1997; 2: 64\u201378.","DOI":"10.1037\/\/1082-989X.2.1.64"},{"key":"48553","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1037\/1082-989X.2.1.64","DOI":"10.1037\/1082-989X.2.1.64"},{"key":"48554","doi-asserted-by":"crossref","unstructured":"Bates D, M\u00e4chler M, Bolker B, Walker S. Fitting Linear Mixed-Effects Models Using lme4. J Stat Softw 2015; 67: 1\u201348.","DOI":"10.18637\/jss.v067.i01"},{"key":"48555","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.18637\/jss.v067.i01","DOI":"10.18637\/jss.v067.i01"},{"key":"48556","doi-asserted-by":"crossref","unstructured":"Treede R-D, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, et al. Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11). Pain 2019; 160: 19\u201327.","DOI":"10.1097\/j.pain.0000000000001384"},{"key":"48557","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/j.pain.0000000000001384","DOI":"10.1097\/j.pain.0000000000001384"},{"key":"48558","doi-asserted-by":"crossref","unstructured":"Reychler G, De Backer M, Piraux E, Poncin W, Caty G. Physical therapy treatment of hypermobile Ehlers\u2013Danlos syndrome: a systematic review. Am J Med Genet A 2021; 185: 2986\u20132994.","DOI":"10.1002\/ajmg.a.62393"},{"key":"48559","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1002\/ajmg.a.62393","DOI":"10.1002\/ajmg.a.62393"},{"key":"48560","doi-asserted-by":"crossref","unstructured":"Buryk-Iggers S, Mittal N, Santa Mina D, Adams SC, Englesakis M, Rachinsky M, et al. Exercise and rehabilitation in people with Ehlers-Danlos syndrome: a systematic review. Arch Rehabil Res Clin Transl 2022; 4: 100189.","DOI":"10.1016\/j.arrct.2022.100189"},{"key":"48561","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.arrct.2022.100189","DOI":"10.1016\/j.arrct.2022.100189"},{"key":"48562","doi-asserted-by":"crossref","unstructured":"Aubry-Rozier B, Schwitzguebel A, Valerio F, Tanniger J, Paquier C, Berna C, et al. Are patients with hypermobile Ehlers\u2013Danlos syndrome or hypermobility spectrum disorder so different? Rheumatol Int 2021; 41: 1785\u20131794.","DOI":"10.1007\/s00296-021-04968-3"},{"key":"48563","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s00296-021-04968-3","DOI":"10.1007\/s00296-021-04968-3"}],"container-title":["Journal of Rehabilitation Medicine"],"original-title":[],"link":[{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/download\/12431\/45280","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/download\/12431\/45280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T10:45:12Z","timestamp":1707302712000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/view\/12431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,7]]},"references-count":71,"URL":"https:\/\/doi.org\/10.2340\/jrm.v56.12431","relation":{},"ISSN":["1651-2081"],"issn-type":[{"value":"1651-2081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,7]]}}}