{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:36:50Z","timestamp":1790757410490,"version":"4.1.0"},"reference-count":58,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JRM"],"abstract":"<jats:p>Objective: Evaluate cost, effectiveness and cost-effectiveness of cognitive behavioural therapy for sleep and fatigue (CBT-SF) vs health education (HE) and of CBT-SF vs treatment as usual (TAU) for sleep disturbance and fatigue in acquired brain injury.\nDesign: Economic evaluation from Australian health system and societal perspectives based on data from a June 2017 to October 2023 randomized controlled trial.\nSubjects: Community-dwelling Australian adults with sleep disturbance and fatigue following acquired brain injury (n\u2009=\u2009126).\nMethods: Incremental health system costs based on cost of delivery and health service utilization since last follow-up. Incremental effectiveness based on participant-reported sleep quality, fatigue, and quality of life at each timepoint. Productivity gains\/lossesbased on a 1-week activity diary at each timepoint.\nResults: Reductions in health service utilization from CBT-SF (\u2013A$777, 95% CI: \u2013A$4,232, A$2,678) offset higher delivery costs (A$333, 95% CI: A$109, A$556) relative to HE, with improvements in quality of life at 2 months post-treatment (0.02, 95% CI: \u20130.01, 0.05) and an additional 3.37 quality-adjusted life days per participant (95% CI: \u20134.18, 10.92). CBT-SF dominates HE (less costly and more effective) and is likely more cost-effective than HE (66\u201376%). CBT-SF is cost-effective relative to TAU under realistic assumptions.\nConclusions: CBT-SF after acquired brain injury improved clinical and economic outcomes and was more likely to be cost-effective than HE. Further research is required to precisely estimate the cost-effectiveness of CBT-SF vs TAU and to demonstrate generalizability to routine practice and other settings.\nANZCTR Trial registration numbers: 1261700087830; 12617000879369.<\/jats:p>","DOI":"10.2340\/jrm.v57.42770","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T06:40:41Z","timestamp":1745563241000},"page":"jrm42770","source":"Crossref","is-referenced-by-count":5,"title":["Cost-effectiveness of cognitive behavioural therapy versus health education for sleep disturbance and fatigue following stroke and traumatic brain injury"],"prefix":"10.2340","volume":"57","author":[{"given":"Duncan","family":"Mortimer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Ymer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"McKay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Frencham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Grima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique","family":"Roper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jade","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gershon","family":"Spitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennie","family":"Ponsford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"108951","doi-asserted-by":"crossref","unstructured":"Hasan F, Gordon C, Dean W, Hui-Chuan H, Yuliana LT, Susatia B, et al. 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