{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:43:40Z","timestamp":1790567020780,"version":"4.1.0"},"reference-count":81,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JRM"],"abstract":"<jats:p>Objectives: Explore exercise intolerance with the Buffalo Concussion Treadmill Test (BCTT) in adult patients with persisting post-concussion symptoms (PCS). Examine the association between exercise intolerance and persistent post-concussion symptom burden. Explore factors associated with the BCTT symptom threshold.\nDesign: Cross-sectional study.\nPatients: 100 patients (mean age 36.9 [SD 10.6] years; 58% women) with mild traumatic brain injury and persistent PCS.\nMethods: Exercise intolerance was assessed using descriptive statistics and group comparisons. Regression models were applied testing the association between exercise intolerance and symptom burden, and to explore factors associated with symptom threshold.\nResults: 81% tested positive for exercise intolerance. Patients with exercise intolerance were younger, had a shorter time since injury, more symptoms, and poorer quality of life. Higher symptom burden was associated with increased odds for exercise intolerance (OR: 1.07, 95%CI: 1.01 to 1.13, p\u2009=\u20090.023). Higher heart rate at start of BCTT was associated with a higher symptom threshold (B: 0.34, 95%CI: 0.17 to \u20130.50, p\u2009\u2009&lt;\u2009\u20090.001), while greater anxiety symptoms were associated with lower symptom threshold (B: \u20130.86, 95%CI: \u20131.6 to \u20130.12, p\u2009&lt;\u20090.023) with R2\u2009=\u20090.21.\nConclusion: Exercise intolerance was confirmed in over 80% of the patients. Assessments of exercise intolerance might contribute to a broader understanding and improved rehabilitation of these patients.<\/jats:p>","DOI":"10.2340\/jrm.v57.43931","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T07:12:56Z","timestamp":1762413176000},"page":"jrm43931","source":"Crossref","is-referenced-by-count":4,"title":["Exploring exercise intolerance in adult patients with persistent post-concussion symptoms after mild traumatic brain injury"],"prefix":"10.2340","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1845-5823","authenticated-orcid":false,"given":"Lars-Johan V.","family":"Valaas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6908-7480","authenticated-orcid":false,"given":"Helene L.","family":"Soberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari S.","family":"Rasmussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4261-6919","authenticated-orcid":false,"given":"Sophie E.","family":"Steenstrup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingerid","family":"Kleffelg\u00e5rd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2025,11,5]]},"reference":[{"key":"132046","doi-asserted-by":"crossref","unstructured":"Kozlowski KF, Graham J, Leddy JJ, Devinney-Boymel L, Willer BS. Exercise intolerance in individuals with postconcussion syndrome. J Athl Train 2013; 48: 627\u2013635.","DOI":"10.4085\/1062-6050-48.5.02"},{"key":"132047","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.4085\/1062-6050-48.5.02","DOI":"10.4085\/1062-6050-48.5.02"},{"key":"132048","doi-asserted-by":"crossref","unstructured":"Fyffe A, Carron MA, Orr R, Cassimatis M, Browne G. Greater symptom burden results in reduced exercise tolerance in adolescents following concussion. Brain Inj 2022; 36: 368\u2013374.","DOI":"10.1080\/02699052.2022.2034964"},{"key":"132049","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1080\/02699052.2022.2034964","DOI":"10.1080\/02699052.2022.2034964"},{"key":"132050","doi-asserted-by":"crossref","unstructured":"Antonellis P, Campbell KR, Wilhelm JL, Shaw JD, Chesnutt JC, King LA. Exercise intolerance after mild traumatic brain injury occurs in all subtypes in the adult population. J Neurotrauma 2024; 41: 635\u2013645.","DOI":"10.1089\/neu.2023.0168"},{"key":"132051","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1089\/neu.2023.0168","DOI":"10.1089\/neu.2023.0168"},{"key":"132052","unstructured":"Ntikas M, Stewart W, Ietswaart M, Hunter AM, Maas AIR, Menon DK, et al. Contrasting characteristics and outcomes of sports-related and non-sports-related traumatic brain injury. JAMA Netw Open 2024; 7: e2353318."},{"key":"132053","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2023.53318","DOI":"10.1001\/jamanetworkopen.2023.53318"},{"key":"132054","doi-asserted-by":"crossref","unstructured":"Carroll LJ, Cassidy JD, Holm L, Kraus J, Coronado VG, Injury WHOCCTFoMTB. Methodological issues and research recommendations for mild traumatic brain injury: the WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury. J Rehabil Med 2004; Suppl 43: 113\u2013125.","DOI":"10.1080\/16501960410023877"},{"key":"132055","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1080\/16501960410023877","DOI":"10.1080\/16501960410023877"},{"key":"132056","doi-asserted-by":"crossref","unstructured":"Voormolen DC, Haagsma JA, Polinder S, Maas AIR, Steyerberg EW, Vulekovic P, et al. Post-concussion symptoms in complicated vs. uncomplicated mild traumatic brain injury patients at three and six months post-injury: results from the CENTER-TBI Study. J Clin Med 2019; 8.","DOI":"10.3390\/jcm8111921"},{"key":"132057","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3390\/jcm8111921","DOI":"10.3390\/jcm8111921"},{"key":"132058","doi-asserted-by":"crossref","unstructured":"Mercier LJ, McIntosh SJ, Boucher C, Joyce JM, Batycky J, Galarneau JM, et al. Effect of aerobic exercise on symptom burden and quality of life in adults with persisting post-concussive symptoms: the ACTBI Randomized Controlled Trial. Arch Phys Med Rehabil 2024; https:\/\/doi.org\/10.1016\/j.apmr.2024.10.002","DOI":"10.1016\/j.apmr.2024.10.002"},{"key":"132059","doi-asserted-by":"crossref","unstructured":"Silverberg ND, Otamendi T. Advice to rest for more than 2 days after mild traumatic brain injury is associated with delayed return to productivity: a case-control study. Front Neurol 2019; 10: 362.","DOI":"10.3389\/fneur.2019.00362"},{"key":"132060","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3389\/fneur.2019.00362","DOI":"10.3389\/fneur.2019.00362"},{"key":"132061","doi-asserted-by":"crossref","unstructured":"Leddy JJ, Haider MN, Ellis MJ, Mannix R, Darling SR, Freitas MS, et al. Early subthreshold aerobic exercise for sport-related concussion: a randomized clinical trial. JAMA Pediatr 2019; 173: 319\u2013325.","DOI":"10.1001\/jamapediatrics.2018.4397"},{"key":"132062","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1001\/jamapediatrics.2018.4397","DOI":"10.1001\/jamapediatrics.2018.4397"},{"key":"132063","doi-asserted-by":"crossref","unstructured":"Leddy JJ, Baker JG, Kozlowski K, Bisson L, Willer B. Reliability of a graded exercise test for assessing recovery from concussion. Clin J Sport Med 2011; 21: 89\u201394.","DOI":"10.1097\/JSM.0b013e3181fdc721"},{"key":"132064","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/JSM.0b013e3181fdc721","DOI":"10.1097\/JSM.0b013e3181fdc721"},{"key":"132065","doi-asserted-by":"crossref","unstructured":"DeGroot A, Huber DL, Leddy JJ, Raff H, McCrea MA, Johnson BD, et al. Use of the Buffalo Concussion Treadmill Test in community adult patients with mild traumatic brain injury. PM R 2024; 16: 826\u2013835.","DOI":"10.1002\/pmrj.13132"},{"key":"132066","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1002\/pmrj.13132","DOI":"10.1002\/pmrj.13132"},{"key":"132067","doi-asserted-by":"crossref","unstructured":"Galea O, O\u2019Leary S, Treleaven J. An investigation of physiological system impairments in individuals 4 weeks to 6 months following mild traumatic brain injury. J Head Trauma Rehabil 2023; 38: E79\u2013E87.","DOI":"10.1097\/HTR.0000000000000783"},{"key":"132068","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/HTR.0000000000000783","DOI":"10.1097\/HTR.0000000000000783"},{"key":"132069","doi-asserted-by":"crossref","unstructured":"Patricios JS, Schneider KJ, Dvorak J, Ahmed OH, Blauwet C, Cantu RC, et al. Consensus statement on concussion in sport: the 6th International Conference on Concussion in Sport\u2013Amsterdam, October 2022. Br J Sports Med 2023; 57: 695\u2013711.","DOI":"10.1136\/bjsports-2023-106898"},{"key":"132070","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1136\/bjsports-2023-106898","DOI":"10.1136\/bjsports-2023-106898"},{"key":"132071","doi-asserted-by":"crossref","unstructured":"Pelo R, Suttman E, Fino PC, McFarland MM, Dibble LE, Cortez MM. Autonomic dysfunction and exercise intolerance in concussion: a scoping review. Clin Auton Res 2023; 33: 149\u2013163.","DOI":"10.1007\/s10286-023-00937-x"},{"key":"132072","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s10286-023-00937-x","DOI":"10.1007\/s10286-023-00937-x"},{"key":"132073","doi-asserted-by":"crossref","unstructured":"Mercier LJ, Batycky J, Campbell C, Schneider K, Smirl J, Debert CT. Autonomic dysfunction in adults following mild traumatic brain injury: a systematic review. NeuroRehabilitation 2022; 50: 3\u201332.","DOI":"10.3233\/NRE-210243"},{"key":"132074","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3233\/NRE-210243","DOI":"10.3233\/NRE-210243"},{"key":"132075","doi-asserted-by":"crossref","unstructured":"Quatman-Yates CC, Hunter-Giordano A, Shimamura KK, Landel R, Alsalaheen BA, Hanke TA, et al. Physical therapy evaluation and treatment after concussion\/mild traumatic brain injury. J Orthop Sports Phys Ther 2020; 50: CPG1\u2013CPG73.","DOI":"10.2519\/jospt.2020.0301"},{"key":"132076","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.2519\/jospt.2020.0301","DOI":"10.2519\/jospt.2020.0301"},{"key":"132077","doi-asserted-by":"crossref","unstructured":"DiFazio M, Silverberg ND, Kirkwood MW, Bernier R, Iverson GL. Prolonged activity restriction after concussion: are we worsening outcomes? Clin Pediatr (Phila) 2016; 55: 443\u2013451.","DOI":"10.1177\/0009922815589914"},{"key":"132078","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1177\/0009922815589914","DOI":"10.1177\/0009922815589914"},{"key":"132079","doi-asserted-by":"crossref","unstructured":"Tverdal C, Aarhus M, Ronning P, Skaansar O, Skogen K, Andelic N, et al. Incidence of emergency neurosurgical TBI procedures: a population-based study. BMC Emerg Med 2022; 22: 1.","DOI":"10.1186\/s12873-021-00561-w"},{"key":"132080","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1186\/s12873-021-00561-w","DOI":"10.1186\/s12873-021-00561-w"},{"key":"132081","doi-asserted-by":"crossref","unstructured":"Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Back M, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J 2021; 42: 3227\u20133337.","DOI":"10.1093\/eurheartj\/ehab484"},{"key":"132082","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1093\/eurheartj\/ehab484","DOI":"10.1093\/eurheartj\/ehab484"},{"key":"132083","doi-asserted-by":"crossref","unstructured":"Williams DH, Levin HS, Eisenberg HM. Mild head injury classification. Neurosurgery 1990; 27: 422\u2013428.","DOI":"10.1227\/00006123-199009000-00014"},{"key":"132084","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/00006123-199009000-00014","DOI":"10.1097\/00006123-199009000-00014"},{"key":"132085","doi-asserted-by":"crossref","unstructured":"Borg G. Perceived exertion as an indicator of somatic stress. Scand J Rehabil Med 1970; 2: 92\u201398","DOI":"10.2340\/1650197719702239298"},{"key":"132086","doi-asserted-by":"crossref","unstructured":"Nes BM, Janszky I, Wisloff U, Stoylen A, Karlsen T. Age-predicted maximal heart rate in healthy subjects: the HUNT fitness study. Scand J Med Sci Sports 2013; 23: 697\u2013704.","DOI":"10.1111\/j.1600-0838.2012.01445.x"},{"key":"132087","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/j.1600-0838.2012.01445.x","DOI":"10.1111\/j.1600-0838.2012.01445.x"},{"key":"132088","doi-asserted-by":"crossref","unstructured":"King NS, Crawford S, Wenden FJ, Moss NE, Wade DT. The Rivermead Post Concussion Symptoms Questionnaire: a measure of symptoms commonly experienced after head injury and its reliability. J Neurol 1995; 242: 587\u2013592.","DOI":"10.1007\/BF00868811"},{"key":"132089","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/BF00868811","DOI":"10.1007\/BF00868811"},{"key":"132090","doi-asserted-by":"crossref","unstructured":"von Steinbuechel N, Wilson L, Gibbons H, Muehlan H, Schmidt H, Schmidt S, et al. QOLIBRI overall scale: a brief index of health-related quality of life after traumatic brain injury. J Neurol Neurosurg Psychiatry 2012; 83: 1041\u20131047.","DOI":"10.1136\/jnnp-2012-302361"},{"key":"132091","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1136\/jnnp-2012-302361","DOI":"10.1136\/jnnp-2012-302361"},{"key":"132092","doi-asserted-by":"crossref","unstructured":"Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med 2001; 16: 606\u2013613.","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"132093","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1046\/j.1525-1497.2001.016009606.x","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"132094","doi-asserted-by":"crossref","unstructured":"Spitzer RL, Kroenke K, Williams JB, Lowe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med 2006; 166: 1092\u20131097.","DOI":"10.1001\/archinte.166.10.1092"},{"key":"132095","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1001\/archinte.166.10.1092","DOI":"10.1001\/archinte.166.10.1092"},{"key":"132096","doi-asserted-by":"crossref","unstructured":"Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale: application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol 1989; 46: 1121\u20131123.","DOI":"10.1001\/archneur.1989.00520460115022"},{"key":"132097","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1001\/archneur.1989.00520460115022","DOI":"10.1001\/archneur.1989.00520460115022"},{"key":"132098","doi-asserted-by":"crossref","unstructured":"Craig CL, Marshall AL, Sjostrom M, Bauman AE, Booth ML, Ainsworth BE, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc 2003; 35: 1381\u20131395.","DOI":"10.1249\/01.MSS.0000078924.61453.FB"},{"key":"132099","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1249\/01.MSS.0000078924.61453.FB","DOI":"10.1249\/01.MSS.0000078924.61453.FB"},{"key":"132100","doi-asserted-by":"crossref","unstructured":"Valaas LV, Soberg HL, Rasmussen MS, Steenstrup SE, Andelic N, Kleffelgard I. Sub-symptom threshold aerobic exercise for patients with persisting post-concussion symptoms and exercise intolerance after mild traumatic brain injury: a study protocol with a nested feasibility study for a randomized controlled trial. BMC Neurol 2023; 23: 179.","DOI":"10.1186\/s12883-023-03221-7"},{"key":"132101","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1186\/s12883-023-03221-7","DOI":"10.1186\/s12883-023-03221-7"},{"key":"132102","unstructured":"Therneau T. A package for survival analysis in R. R package version 3.5-8. 2024; 2024. Available from: https:\/\/cran.r-project.org\/web\/packages\/survival\/vignettes\/survival.pdf"},{"key":"132103","doi-asserted-by":"crossref","unstructured":"Howe EI, Zeldovich M, Andelic N, von Steinbuechel N, Fure SCR, Borgen IMH, et al. Rehabilitation and outcomes after complicated vs uncomplicated mild TBI: results from the CENTER-TBI study. BMC Health Serv Res 2022; 22: 1536.","DOI":"10.1186\/s12913-022-07585-3"},{"key":"132104","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1186\/s12913-022-08908-0","DOI":"10.1186\/s12913-022-08908-0"},{"key":"132105","doi-asserted-by":"crossref","unstructured":"Vuu S, Barr CJ, Killington M, Howie J, Hutchins S, van den Berg MEL. The Buffalo Concussion Treadmill and Bike Tests in people with mild-to-moderate traumatic brain injury: an exploratory clinical audit. J Head Trauma Rehabil 2023; 38: E414\u2013E423.","DOI":"10.1097\/HTR.0000000000000879"},{"key":"132106","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/HTR.0000000000000879","DOI":"10.1097\/HTR.0000000000000879"},{"key":"132107","doi-asserted-by":"crossref","unstructured":"Thorne J, Hellewell SC, Cowen G, Ring A, Jefferson A, Chih H, et al. Symptoms associated with exercise intolerance and resting heart rate following mild traumatic brain injury. J Head Trauma Rehabil 2024; 39: E381\u2013E392.","DOI":"10.1097\/HTR.0000000000000928"},{"key":"132108","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/HTR.0000000000000928","DOI":"10.1097\/HTR.0000000000000928"},{"key":"132109","doi-asserted-by":"crossref","unstructured":"Lambert M, Sheldrake E, Deneault AA, Wheeler A, Burke M, Scratch S. Depressive symptoms in individuals with persistent postconcussion symptoms: a systematic review and meta-analysis. JAMA Netw Open 2022; 5: e2248453.","DOI":"10.1001\/jamanetworkopen.2022.48453"},{"key":"132110","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2022.48453","DOI":"10.1001\/jamanetworkopen.2022.48453"},{"key":"132111","doi-asserted-by":"crossref","unstructured":"Machamer J, Temkin N, Dikmen S, Nelson LD, Barber J, Hwang P, et al. Symptom frequency and persistence in the first year after traumatic brain injury: a TRACK-TBI Study. J Neurotrauma 2022; 39: 358\u2013370.","DOI":"10.1089\/neu.2021.0348"},{"key":"132112","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1089\/neu.2021.0348","DOI":"10.1089\/neu.2021.0348"},{"key":"132113","doi-asserted-by":"crossref","unstructured":"Zeldovich M, Bockhop F, Covic A, Mueller I, Polinder S, Mikolic A, et al. Factorial validity and comparability of the six translations of the Rivermead Post-Concussion Symptoms Questionnaire translations: results from the CENTER-TBI study. J Patient Rep Outcomes 2023; 7: 90.","DOI":"10.21203\/rs.3.rs-2886101\/v2"},{"key":"132114","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1186\/s41687-023-00632-5","DOI":"10.1186\/s41687-023-00632-5"},{"key":"132115","doi-asserted-by":"crossref","unstructured":"Haider MN, Lutnick E, Nazir MSZ, Nowak A, Chizuk HM, Miecznikowski JC, et al. Sensitivity and specificity of exercise intolerance on graded exertion testing for diagnosing sport-related concussion: a systematic review and exploratory meta-analysis. J Neurotrauma 2023; 40: 1524\u20131532.","DOI":"10.1089\/neu.2022.0331"},{"key":"132116","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1089\/neu.2022.0331","DOI":"10.1089\/neu.2022.0331"},{"key":"132117","doi-asserted-by":"crossref","unstructured":"Leddy JJ, Master CL, Mannix R, Wiebe DJ, Grady MF, -Meehan WP, et al. Early targeted heart rate aerobic -exercise versus placebo stretching for sport-related concussion in adolescents: a randomised controlled trial. Lancet Child Adolesc Health 2021; 5: 792\u2013799.","DOI":"10.1016\/S2352-4642(21)00267-4"},{"key":"132118","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/S2352-4642(21)00267-4","DOI":"10.1016\/S2352-4642(21)00267-4"},{"key":"132119","doi-asserted-by":"crossref","unstructured":"Medvedev ON, Theadom A, Barker-Collo S, Feigin V, Group BR. Distinguishing between enduring and dynamic concussion symptoms: applying Generalisability Theory to the Rivermead Post Concussion Symptoms Questionnaire (RPQ). PeerJ 2018; 6: e5676.","DOI":"10.7717\/peerj.5676"},{"key":"132120","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.7717\/peerj.5676","DOI":"10.7717\/peerj.5676"},{"key":"132121","doi-asserted-by":"crossref","unstructured":"Mercier LJ, McIntosh SJ, Burma JS, Batycky J, Joyce JM, Galarneau JM, et al. Altered autonomic cardiovascular function in adults with persisting post-concussive symptoms and exercise intolerance. Physiol Rep 2025; 13: e70378.","DOI":"10.14814\/phy2.70378"},{"key":"132122","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.14814\/phy2.70378","DOI":"10.14814\/phy2.70378"},{"key":"132123","doi-asserted-by":"crossref","unstructured":"Haider MN, Leddy JJ, Wilber CG, Viera KB, Bezherano I, Wilkins KJ, et al. The predictive capacity of the Buffalo Concussion Treadmill Test after sport-related concussion in adolescents. Front Neurol 2019; 10: 395.","DOI":"10.3389\/fneur.2019.00395"},{"key":"132124","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3389\/fneur.2019.00395","DOI":"10.3389\/fneur.2019.00395"},{"key":"132125","doi-asserted-by":"crossref","unstructured":"Mercier LJ, Kowalski K, Fung TS, Joyce JM, Yeates KO, Debert CT. Characterizing physical activity and sedentary behavior in adults with persistent postconcussive symptoms after mild traumatic brain injury. Arch Phys Med Rehabil 2021; 102: 1918\u20131925 e1911.","DOI":"10.1016\/j.apmr.2021.05.002"},{"key":"132126","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.apmr.2021.05.002","DOI":"10.1016\/j.apmr.2021.05.002"}],"container-title":["Journal of Rehabilitation Medicine"],"original-title":[],"link":[{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/download\/43931\/51931","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/download\/43931\/51931","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T07:13:23Z","timestamp":1762413203000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/view\/43931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,5]]},"references-count":81,"URL":"https:\/\/doi.org\/10.2340\/jrm.v57.43931","relation":{},"ISSN":["1651-2081"],"issn-type":[{"value":"1651-2081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,5]]}}}