{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:24:36Z","timestamp":1788305076180,"version":"build-2803163510"},"reference-count":81,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:00:00Z","timestamp":1761091200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JRM"],"abstract":"<jats:p>Objective: Pre-dialysis exercise training may benefit haemodialysis patients, but the effects of structured aerobic and resistance training remain unclear. This study evaluated the effects of a 6-month training performed 1\u20132 h before haemodialysis on muscle strength, cardiorespiratory fitness, quality of life, and systemic inflammation.\nDesign: A 3-phase self-controlled design: 3-month control, 6-month aerobic and resistance training (72 sessions) and nutrition counselling, and 3-month follow-up.\nPatients: Haemodialysis patients &gt;\u20093 months.\nMethods: Assessments were performed every 3 months at 5 time points. Outcomes included physical fitness (dual-energy X-ray absorptiometry, isokinetic dynamometry, and cardiopulmonary exercise testing), Kidney Disease QOL questionnaire, International Physical Activity Questionnaire, nutrition, and plasma pro- and anti-inflammatory cytokines.\nResults: Of 118 patients screened, 29 entered training and 22 completed 72 sessions (92% compliance). Pre-dialysis exercise training improved muscle mass, cardiorespiratory fitness, quadriceps strength, physical and mental components, and disease-specific quality of life; cardiorespiratory fitness and strength declined at 3-month follow-up, but muscle mass remained. Cytokine levels were unchanged, suggesting minimal pro- or anti-inflammatory effects.\nConclusion: A 6-month pre-dialysis exercise programme improved cardiorespiratory fitness, strength, muscle mass, and quality of life with high compliance. It may be viable for haemodialysis patients, though maintenance is needed to sustain benefits.\nClinicalTrials.gov ID: NCT05649657<\/jats:p>","DOI":"10.2340\/jrm.v57.44067","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T05:20:49Z","timestamp":1761196849000},"page":"jrm44067","source":"Crossref","is-referenced-by-count":2,"title":["From gains to decline: effects of structured pre-dialytic exercise training and detraining on physical fitness, quality of life, and inflammation in haemodialysis patients"],"prefix":"10.2340","volume":"57","author":[{"given":"Shu-Chun","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Tseng","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chieh","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Yueh","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Chung","family":"Hsiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2025,10,22]]},"reference":[{"key":"130490","doi-asserted-by":"crossref","unstructured":"Jager KJ, Kovesdy C, Langham R, Rosenberg M, Jha V, Zoccali C. A single number for advocacy and communication: worldwide more than 850 million individuals have kidney diseases. Nephrol Dial Transplant 2019; 34: 1803\u20131805.","DOI":"10.1093\/ndt\/gfz174"},{"key":"130491","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1093\/ndt\/gfz174","DOI":"10.1093\/ndt\/gfz174"},{"key":"130492","doi-asserted-by":"crossref","unstructured":"Clarkson MJ, Bennett PN, Fraser SF, Warmington SA. Exercise interventions for improving objective physical function in patients with end-stage kidney disease on dialysis: a systematic review and meta-analysis. Am J Physiol Renal Physiol 2019; 316: F856\u2013872.","DOI":"10.1152\/ajprenal.00317.2018"},{"key":"130493","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1152\/ajprenal.00317.2018","DOI":"10.1152\/ajprenal.00317.2018"},{"key":"130494","doi-asserted-by":"crossref","unstructured":"Al-Mallah MH, Sakr S, Al-Qunaibet A. Cardiorespiratory fitness and cardiovascular disease prevention: an update. Curr Atheroscler Rep 2018; 20: 1.","DOI":"10.1007\/s11883-018-0711-4"},{"key":"130495","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s11883-018-0711-4","DOI":"10.1007\/s11883-018-0711-4"},{"key":"130496","doi-asserted-by":"crossref","unstructured":"Wathanavasin W, Banjongjit A, Avihingsanon Y, Praditpornsilpa K, Tungsanga K, Eiam-Ong S, et al. Prevalence of sarcopenia and its impact on cardiovascular events and mortality among dialysis patients: a systematic review and meta-analysis. Nutrients 2022; 30; 14: 4077.","DOI":"10.3390\/nu14194077"},{"key":"130497","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3390\/nu14194077","DOI":"10.3390\/nu14194077"},{"key":"130498","doi-asserted-by":"crossref","unstructured":"Wu YY, Li JY, Xia QJ, Gao YY, Zhang C, Xu PJ, et al. Analysis of risk factors of sarcopenia in patients with maintenance hemodialysis and its correlation with emotional status and quality of life. J Multidiscip Healthc 2024; 17: 3743\u20133751.","DOI":"10.2147\/JMDH.S469900"},{"key":"130499","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.2147\/JMDH.S469900","DOI":"10.2147\/JMDH.S469900"},{"key":"130500","doi-asserted-by":"crossref","unstructured":"Johansen KL, Chertow GM, Ng AV, Mulligan K, Carey S, Schoenfeld PY, et al. Physical activity levels in patients on hemodialysis and healthy sedentary controls. Kidney Int 2000; 57: 2564\u20132570.","DOI":"10.1046\/j.1523-1755.2000.00116.x"},{"key":"130501","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1046\/j.1523-1755.2000.00116.x","DOI":"10.1046\/j.1523-1755.2000.00116.x"},{"key":"130502","doi-asserted-by":"crossref","unstructured":"Matsuzawa R, Hoshi K, Yoneki K, Harada M, Watanabe T, Shimoda T, et al. Exercise training in elderly people undergoing hemodialysis: a systematic review and meta-analysis. Kidney Int Rep 2017; 2: 1096\u20131110.","DOI":"10.1016\/j.ekir.2017.06.008"},{"key":"130503","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.ekir.2017.06.008","DOI":"10.1016\/j.ekir.2017.06.008"},{"key":"130504","doi-asserted-by":"crossref","unstructured":"Jung TD, Park SH. Intradialytic exercise programs for hemodialysis patients. Chonnam Med J 2011; 47: 61\u201365.","DOI":"10.4068\/cmj.2011.47.2.61"},{"key":"130505","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.4068\/cmj.2011.47.2.61","DOI":"10.4068\/cmj.2011.47.2.61"},{"key":"130506","doi-asserted-by":"crossref","unstructured":"Konstantinidou E, Koukouvou G, Kouidi E, Deligiannis A, Tourkantonis A. Exercise training in patients with end-stage renal disease on hemodialysis: comparison of three rehabilitation programs. J Rehabil Med 2002; 34: 40\u201345.","DOI":"10.1080\/165019702317242695"},{"key":"130507","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1080\/165019702317242695","DOI":"10.1080\/165019702317242695"},{"key":"130508","doi-asserted-by":"crossref","unstructured":"van Vilsteren MC, de Greef MH, Huisman RM. The effects of a low-to-moderate intensity pre-conditioning exercise programme linked with exercise counselling for sedentary haemodialysis patients in The Netherlands: results of a randomized clinical trial. Nephrol Dial Transplant 2005; 20: 141\u2013146.","DOI":"10.1093\/ndt\/gfh560"},{"key":"130509","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1093\/ndt\/gfh560","DOI":"10.1093\/ndt\/gfh560"},{"key":"130510","doi-asserted-by":"crossref","unstructured":"Dong J, Sundell MB, Pupim LB, Wu P, Shintani A, Ikizler TA. The effect of resistance exercise to augment long-term benefits of intradialytic oral nutritional supplementation in chronic hemodialysis patients. J Ren Nutr 2011; 21: 149\u2013159.","DOI":"10.1053\/j.jrn.2010.03.004"},{"key":"130511","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1053\/j.jrn.2010.03.004","DOI":"10.1053\/j.jrn.2010.03.004"},{"key":"130512","doi-asserted-by":"crossref","unstructured":"Song WJ, Sohng KY. Effects of progressive resistance training on body composition, physical fitness and quality of life of patients on hemodialysis. J Korean Acad Nurs 2012; 42: 947\u2013956.","DOI":"10.4040\/jkan.2012.42.7.947"},{"key":"130513","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.4040\/jkan.2012.42.7.947","DOI":"10.4040\/jkan.2012.42.7.947"},{"key":"130514","doi-asserted-by":"crossref","unstructured":"Gadelha AB, Cesari M, Corr\u00eaa HL, Neves RVP, Sousa CV, Deus LA, et al. Effects of pre-dialysis resistance training on sarcopenia, inflammatory profile, and anemia biomarkers in older community-dwelling patients with chronic kidney disease: a randomized controlled trial. Int Urol Nephrol 2021; 53: 2137\u20132147.","DOI":"10.1007\/s11255-021-02799-6"},{"key":"130515","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s11255-021-02799-6","DOI":"10.1007\/s11255-021-02799-6"},{"key":"130516","doi-asserted-by":"crossref","unstructured":"Cho H, Sohng KY. The effect of a virtual reality exercise program on physical fitness, body composition, and fatigue in hemodialysis patients. J Phys Ther Sci 2014; 26: 1661\u20131665.","DOI":"10.1589\/jpts.26.1661"},{"key":"130517","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1589\/jpts.26.1661","DOI":"10.1589\/jpts.26.1661"},{"key":"130518","doi-asserted-by":"crossref","unstructured":"Sabatino A, Cuppari L, Stenvinkel P, Lindholm B, Avesani CM. Sarcopenia in chronic kidney disease: what have we learned so far? J Nephrol 2021; 34: 1347\u20131372.","DOI":"10.1007\/s40620-020-00840-y"},{"key":"130519","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s40620-020-00840-y","DOI":"10.1007\/s40620-020-00840-y"},{"key":"130520","doi-asserted-by":"crossref","unstructured":"Mel\u00e9ndez Oliva E, Villafa\u00f1e JH, Alonso P\u00e9rez JL, Alonso Sal A, Molinero Carlier G, Quevedo Garc\u00eda A, et al. Effect of exercise on inflammation in hemodialysis patients: a systematic review. J Pers Med 2022; 12: 1188.","DOI":"10.3390\/jpm12071188"},{"key":"130521","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3390\/jpm12071188","DOI":"10.3390\/jpm12071188"},{"key":"130522","unstructured":"Brawner A. C. Exercise prescription for individuals with cardiovascular and pulmonary diseases. In: Riebe D, Ehrman JK, Liguori G, editors. ACSM\u2019s guidelines for exercise testing and prescription, 11th ed. Baltimore: Lippincott Williams & Wilkins; 2021: p. 377\u2013378."},{"key":"130523","unstructured":"Liguori G, Medicine ACoS. ACSM\u2019s guidelines for exercise testing and prescription. Baltimore: Lippincott Williams & Wilkins; 2020."},{"key":"130524","doi-asserted-by":"crossref","unstructured":"Huang SC, Wong MK, Lin PJ, Tsai FC, Fu TC, Wen MS, et al. Modified high-intensity interval training increases peak cardiac power output in patients with heart failure. Eur J Appl Physiol 2014; 114: 1853\u20131862.","DOI":"10.1007\/s00421-014-2913-y"},{"key":"130525","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s00421-014-2913-y","DOI":"10.1007\/s00421-014-2913-y"},{"key":"130526","doi-asserted-by":"crossref","unstructured":"Danneskiold-Sams\u00f8e B, Bartels EM, B\u00fclow PM, Lund H, Stockmarr A, Holm CC, et al. Isokinetic and isometric muscle strength in a healthy population with special reference to age and gender. Acta Physiol 2009; 197: 1\u201368.","DOI":"10.1111\/j.1748-1716.2009.02022.x"},{"key":"130527","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/j.1748-1716.2009.02022.x","DOI":"10.1111\/j.1748-1716.2009.02022.x"},{"key":"130528","doi-asserted-by":"crossref","unstructured":"Wilkinson TJ, Watson EL, Xenophontos S, Gould DW, Smith AC. The \u201cminimum clinically important difference\u201d in frequently reported objective physical function tests after a 12-week renal rehabilitation exercise intervention in nondialysis chronic kidney disease. Am J Phys Med Rehabil 2019; 98: 431\u2013437.","DOI":"10.1097\/PHM.0000000000001080"},{"key":"130529","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/PHM.0000000000001080","DOI":"10.1097\/PHM.0000000000001080"},{"key":"130530","doi-asserted-by":"crossref","unstructured":"Gomes Neto M, de Lacerda FFR, Lopes AA, Martinez BP, Saquetto MB. Intradialytic exercise training modalities on physical functioning and health-related quality of life in patients undergoing maintenance hemodialysis: systematic review and meta-analysis. Clin Rehabil 2018; 32: 1189\u20131202.","DOI":"10.1177\/0269215518760380"},{"key":"130531","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1177\/0269215518760380","DOI":"10.1177\/0269215518760380"},{"key":"130532","doi-asserted-by":"crossref","unstructured":"Lu Y, Wang Y, Lu Q. Effects of exercise on muscle fitness in dialysis patients: a systematic review and meta-analysis. Am J Nephrol 2019; 50: 291\u2013302.","DOI":"10.1159\/000502635"},{"key":"130533","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1159\/000502635","DOI":"10.1159\/000502635"},{"key":"130534","doi-asserted-by":"crossref","unstructured":"Hecking M, Karaboyas A, Antlanger M, Saran R, Wizemann V, Chazot C, et al. Significance of interdialytic weight gain versus chronic volume overload: consensus opinion. Am J Nephrol 2013; 38: 78\u201390.","DOI":"10.1159\/000353104"},{"key":"130535","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1159\/000353104","DOI":"10.1159\/000353104"},{"key":"130536","doi-asserted-by":"crossref","unstructured":"Wilund KR, Jeong JH, Greenwood SA. Addressing myths about exercise in hemodialysis patients. Semin Dial 2019; 32: 297\u2013302.","DOI":"10.1111\/sdi.12815"},{"key":"130537","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1111\/sdi.12815","DOI":"10.1111\/sdi.12815"},{"key":"130538","doi-asserted-by":"crossref","unstructured":"Hsiao CC, Chou CY, Fang JT, Chang SC, Liu KC, Huang SC. Cardiopulmonary response to acute exercise before hemodialysis: a pilot study. Kidney Blood Press Res 2024; 49: 735\u2013744.","DOI":"10.1159\/000540767"},{"key":"130539","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1159\/000540767","DOI":"10.1159\/000540767"},{"key":"130540","doi-asserted-by":"crossref","unstructured":"Ren N, Yang H, Cai Z, Wang R, Wang Z, Zhao Y, et al. Comparative efficacy of nine exercise methods on the prognosis in chronic kidney disease patients with hemodialysis: a systematic review and network meta-analysis. Eur J Med Res 2023; 28: 401.","DOI":"10.1186\/s40001-023-01270-9"},{"key":"130541","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1186\/s40001-023-01270-9","DOI":"10.1186\/s40001-023-01270-9"},{"key":"130542","doi-asserted-by":"crossref","unstructured":"Burnet K, Kelsch E, Zieff G, Moore JB, Stoner L. How fitting is F.I.T.T.?: A perspective on a transition from the sole use of frequency, intensity, time, and type in exercise prescription. Physiol Behav 2019; 199: 33\u201334.","DOI":"10.1016\/j.physbeh.2018.11.007"},{"key":"130543","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.physbeh.2018.11.007","DOI":"10.1016\/j.physbeh.2018.11.007"},{"key":"130544","doi-asserted-by":"crossref","unstructured":"Hu H, Wu C, Kwok JYY, Ho MH, Chau PH, Lok KYW, et al. Effects of different exercises on physical function, dialysis adequacy, and health-related quality of life in maintenance hemodialysis patients: a systematic review and network meta-analysis. Am J Nephrol 2023; 54: 379\u2013390.","DOI":"10.1159\/000532109"},{"key":"130545","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1159\/000532109","DOI":"10.1159\/000532109"},{"key":"130546","doi-asserted-by":"crossref","unstructured":"Stewart AL, Greenfield S, Hays RD, Wells K, Rogers WH, Berry SD, et al. Functional status and well-being of patients with chronic conditions: results from the Medical Outcomes Study. JAMA 1989; 262: 907\u2013913.","DOI":"10.1001\/jama.1989.03430070055030"},{"key":"130547","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1001\/jama.1989.03430070055030","DOI":"10.1001\/jama.1989.03430070055030"},{"key":"130548","doi-asserted-by":"crossref","unstructured":"Strand V, Boers M, Idzerda L, Kirwan JR, Kvien TK, Tugwell PS, et al. It\u2019s good to feel better but it\u2019s better to feel good and even better to feel good as soon as possible for as long as possible: response criteria and the importance of change at OMERACT 10. J Rheumatol 2011; 38: 1720\u20131727.","DOI":"10.3899\/jrheum.110392"},{"key":"130549","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3899\/jrheum.110392","DOI":"10.3899\/jrheum.110392"},{"key":"130550","unstructured":"Hays RD, Kallich J, Mapes D, Coons S, Amin N, Carter W, et al. Kidney disease quality of life short form (KDQOL-SF\u2122), version 1.3: a manual for use and scoring. Santa Monica, CA: Rand; 1997."},{"key":"130551","doi-asserted-by":"crossref","unstructured":"Martin WH 3rd, Coyle EF, Bloomfield SA, Ehsani AA. Effects of physical deconditioning after intense endurance training on left ventricular dimensions and stroke volume. J Am Coll Cardiol 1986; 7: 982\u2013989.","DOI":"10.1016\/S0735-1097(86)80215-7"},{"key":"130552","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/S0735-1097(86)80215-7","DOI":"10.1016\/S0735-1097(86)80215-7"},{"key":"130553","doi-asserted-by":"crossref","unstructured":"Mora-Rodriguez R, Ortega JF, Hamouti N, Fernandez-Elias VE, Ca\u00f1ete Garcia-Prieto J, Guadalupe-Grau A, et al. Time-course effects of aerobic interval training and detraining in patients with metabolic syndrome. Nutr Metab Cardiovasc Dis 2014; 24: 792\u2013798.","DOI":"10.1016\/j.numecd.2014.01.011"},{"key":"130554","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1016\/j.numecd.2014.01.011","DOI":"10.1016\/j.numecd.2014.01.011"},{"key":"130555","doi-asserted-by":"crossref","unstructured":"Mujika I, Padilla S. Cardiorespiratory and metabolic characteristics of detraining in humans. Med Sci Sports Exerc 2001; 33: 413\u2013421.","DOI":"10.1097\/00005768-200103000-00013"},{"key":"130556","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1097\/00005768-200103000-00013","DOI":"10.1097\/00005768-200103000-00013"},{"key":"130557","doi-asserted-by":"crossref","unstructured":"Correa CS, Baroni BM, Radaelli R, Lanferdini FJ, Cunha Gdos S, Reischak-Oliveira \u00c1, et al. Effects of strength training and detraining on knee extensor strength, muscle volume and muscle quality in elderly women. Age (Dordr) 2013; 35: 1899\u20131904.","DOI":"10.1007\/s11357-012-9478-7"},{"key":"130558","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1007\/s11357-012-9478-7","DOI":"10.1007\/s11357-012-9478-7"},{"key":"130559","doi-asserted-by":"crossref","unstructured":"Connelly DM, Vandervoort AA. Effects of detraining on knee extensor strength and functional mobility in a group of elderly women. J Orthop Sports Phys Ther 1997; 26: 340\u2013346.","DOI":"10.2519\/jospt.1997.26.6.340"},{"key":"130560","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.2519\/jospt.1997.26.6.340","DOI":"10.2519\/jospt.1997.26.6.340"},{"key":"130561","doi-asserted-by":"crossref","unstructured":"Grgic J. Use it or lose it? A meta-analysis on the effects of resistance training cessation (detraining) on muscle size in older adults. Int J Environ Res Public Health 2022; 28: 19.","DOI":"10.3390\/ijerph192114048"},{"key":"130562","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3390\/ijerph192114048","DOI":"10.3390\/ijerph192114048"},{"key":"130563","doi-asserted-by":"crossref","unstructured":"Bogataj \u0160, Pajek J, Slonj\u0161ak B, Per\u0161i\u010d V. Prevalence of impaired physical mobility in dialysis patients: a single-centre cross-sectional study. J Clin Med 2023; 20: 12.","DOI":"10.3390\/jcm12206634"},{"key":"130564","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.3390\/jcm12206634","DOI":"10.3390\/jcm12206634"},{"key":"130565","doi-asserted-by":"crossref","unstructured":"Craig CL, Marshall AL, Sj\u00f6str\u00f6m M, Bauman AE, Booth ML, Ainsworth BE, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc 2003; 35: 1381\u20131395.","DOI":"10.1249\/01.MSS.0000078924.61453.FB"},{"key":"130566","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1249\/01.MSS.0000078924.61453.FB","DOI":"10.1249\/01.MSS.0000078924.61453.FB"},{"key":"130567","doi-asserted-by":"crossref","unstructured":"Huang S-C, Wong M-K, Lin P-J, Tsai F-C, Chu J-J, Wu M-Y, et al. Short-term intensive training attenuates the exercise-induced interaction of mono-1\/2 cells and platelets after coronary bypass in cardiac patients. J Thromb Haemost 2017; 117: 1761\u20131771.","DOI":"10.1160\/TH17-03-0184"},{"key":"130568","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1160\/TH17-03-0184","DOI":"10.1160\/TH17-03-0184"},{"key":"130569","doi-asserted-by":"crossref","unstructured":"Huang S-C, Hsu C-C, Fu T-C, Chen CP, Liao M-F, Hsu C-Y, et al. Stepper-based training improves monocyte-platelet aggregation and thrombin generation in nonambulatory hemiplegic patients. Med Sci Sports Exerc 2022; 54: 821\u2013829.","DOI":"10.1249\/MSS.0000000000002846"},{"key":"130570","doi-asserted-by":"crossref","unstructured":"https:\/\/doi.org\/10.1249\/MSS.0000000000002846","DOI":"10.1249\/MSS.0000000000002846"}],"container-title":["Journal of Rehabilitation Medicine"],"original-title":[],"link":[{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/download\/44067\/51801","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/download\/44067\/51801","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T05:21:09Z","timestamp":1761196869000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicaljournalssweden.se\/jrm\/article\/view\/44067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,22]]},"references-count":81,"URL":"https:\/\/doi.org\/10.2340\/jrm.v57.44067","relation":{},"ISSN":["1651-2081"],"issn-type":[{"value":"1651-2081","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,22]]}}}