{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:54:58Z","timestamp":1787169298881,"version":"build-2736575974"},"reference-count":71,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JRM"],"abstract":"<jats:p>Background: Early rehabilitation within 4 h following total knee arthroplasty involves passive exercise with manual therapy.\nObjective: The aim was to determine the beneficial effects of the single-joint hybrid assistive limb forrehabilitation within 4 h after total knee arthroplasty.\nMethods: This single-blinded randomized controlled trial included 68 participants who underwent primary total knee arthroplasty for knee osteoarthritis and were assigned to the early single-joint hybrid assistive limb (n\u2009=\u200922), HAL-SJ (n\u2009=\u200923), and control (n\u2009=\u200923) groups.\nResults: The Knee Injury and Osteoarthritis Outcome Score quality of life (p\u2009=\u20090.007) scores of the early single-joint hybrid assistive limb group showed significantly higher values than the control groups at 12 months. The recovery time for extension lag was significantly improved in the early single-joint hybrid assistive limb group compared with the single-joint hybrid assistive limb (p\u2009=\u20090.006) and control (p\u2009&lt;\u20090.001) groups. Additionally, the knee flexion range of motion of the early single-joint hybrid assistive limb group showed significantly higher values than the single-joint hybrid assistive limb (p\u2009=\u20090.029) and control (p\u2009=\u20090.031) groups at 1\u00a0week.\nConclusions: Early single-joint hybrid assistive limb rehabilitation may improve patient-reported quality of life at 12 months without exacerbating postoperative pain or swelling. These results suggest that the single-joint hybrid assistive limb may be a feasible adjunct to early postoperative rehabilitation after total knee arthroplasty, while further studies are required to clarify its clinical relevance and long-term benefits.<\/jats:p>","DOI":"10.2340\/jrm.v58.43925","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:52:12Z","timestamp":1773125532000},"page":"jrm43925","source":"Crossref","is-referenced-by-count":1,"title":["Effect of early hybrid assistive limb assisted rehabilitation on functional outcomes and patient satisfaction after total knee arthroplasty: a randomized controlled trial"],"prefix":"10.2340","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4122-3457","authenticated-orcid":false,"given":"Takaya","family":"Watabe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryota","family":"Muramatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Sengoku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goro","family":"Sakurai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"143807","doi-asserted-by":"crossref","unstructured":"Tuncay Duruoz M, Oz N, Gursoy DE, Hande Gezer H. 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