{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T16:13:07Z","timestamp":1773159187158,"version":"3.50.1"},"reference-count":37,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SJU"],"abstract":"<jats:p>Objective: Transurethral microwave thermotherapy (TUMT) is well described for lower urinary tract symptoms in men with prostates between 30 and 100 grams. We aimed to describe the results in men with prostates larger than 100 grams.\nMaterial and methods: We retrospectively recorded age, prostate size, occurrence of urinary retention, and Danish Prostate Symptom Score (DAN-PSS) prior to treatment in men with prostates exceeding 100 grams. Following treatment, we assessed satisfaction, DAN-PSS, and the results of uroflowmetry and postvoid residual urine.\nResults: We included 50 consecutive patients with prostates over 100 g. The median age was 78 years, and the median prostate size was 126 g (range 101\u2013230). Forty-four men were treated due to urinary retention and 6 due to lower urinary tract symptoms. Treatments were performed under local anesthesia. The median duration was 15 minutes (range 8\u201332 minutes) and the median destruction was 25% of the prostatic volume (range 11\u201326%). Eight patients had destruction of &lt;20%. No side effects were noted.\nForty-nine patients completed 6-month follow-up. The 41\/49 (84%) men who had tissue destruction of \u226520% reported to be satisfied. The median DAN-PSS score was 3 (range 0\u201318), the median Qmax was 12 mL\/s (range 5.1\u201323.1 mL\/s) and the median postvoid residual volume was 89 mL (range 0\u2013331 mL). Symptoms were unchanged in the 8\/49 (16%) men who had &lt;20% tissue destruction.\nConclusions: TUMT represents a useful alternative to surgery in men with infravesical obstruction and a prostate of more than 100 grams.<\/jats:p>","DOI":"10.2340\/sju.v60.42784","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T12:33:49Z","timestamp":1738758829000},"page":"23-28","source":"Crossref","is-referenced-by-count":2,"title":["Transurethral microwave thermotherapy with the CoreTherm\u00aeConcept in men with prostates larger than 100 grams \u2013 a consecutive case series"],"prefix":"10.2340","volume":"60","author":[{"given":"Lilli","family":"Winck-Flyvholm","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikkel","family":"Fode","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Marsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurt","family":"Kr\u00f8yer Nielsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1183","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"key":"98345","doi-asserted-by":"crossref","unstructured":"Cornu J-N, Dupuis H, Gazdovich S. Hot topics of the past decade: evolutions and revolutions in lower urinary tract symptoms. Eur Urol Focus. 2022;8:371\u2013374. https:\/\/doi.org\/10.1016\/j.euf.2022.03.012","DOI":"10.1016\/j.euf.2022.03.012"},{"key":"98346","doi-asserted-by":"crossref","unstructured":"Franco JV, Garegnani L, Escobar Liquitay CM, et al. Transurethral microwave thermotherapy for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia. Cochrane Database Syst Rev. 2021;6:CD004135. https:\/\/doi.org\/10.1002\/14651858.CD004135.pub4","DOI":"10.1002\/14651858.CD004135.pub4"},{"key":"98347","doi-asserted-by":"crossref","unstructured":"Cornu J-N, Zantek P, Burtt G, et al. Minimally invasive treatments for benign prostatic obstruction: a systematic review and network meta-analysis. Eur Urol. 2023;83:534\u2013547. https:\/\/doi.org\/10.1016\/j.eururo.2023.02.028","DOI":"10.1016\/j.eururo.2023.02.028"},{"key":"98348","doi-asserted-by":"crossref","unstructured":"Stenmark F, Brudin L, Kj\u00f6lhede H, et al. Treatment with CoreTherm in 570 patients with prostate volumes of 80-366 mL: an evaluation of short- and long-term retreatment risk. Scand J Urol. 2022;56:336\u2013341. https:\/\/doi.org\/10.1080\/21681805.2022.2108139","DOI":"10.1080\/21681805.2022.2108139"},{"key":"98349","doi-asserted-by":"crossref","unstructured":"Hansen BJ, Flyger H, Brasso K, et al. Validation of the self-administered Danish Prostatic Symptom Score (DAN-PSS-1) system for use in benign prostatic hyperplasia. Br J Urol. 1995;76(4):451\u2013458.","DOI":"10.1111\/j.1464-410X.1995.tb07744.x"},{"key":"98350","doi-asserted-by":"crossref","unstructured":"Aagaard MF, Niebuhr MH, Jacobsen JD, et al. Transurethral microwave thermotherapy treatment of chronic urinary retention in patients unsuitable for surgery. Scand J Urol. 2014;48:290\u2013294. https:\/\/doi.org\/10.3109\/21681805.2013.840857","DOI":"10.3109\/21681805.2013.840857"},{"key":"98351","doi-asserted-by":"crossref","unstructured":"Larson TR, Blute ML, Bruskewitz RC, et al. A high-efficiency microwave thermoablation system for the treatment of benign prostatic hyperplasia: results of a randomized, sham-controlled, prospective, double-blind, multicenter clinical trial. Urology. 1998;51:731\u2013742. https:\/\/doi.org\/10.1016\/s0090-4295(97)00710-3","DOI":"10.1016\/S0090-4295(97)00710-3"},{"key":"98352","doi-asserted-by":"crossref","unstructured":"Brehmer M, Wiksell H, Kinn A. Sham treatment compared with 30 or 60 min of thermotherapy for benign prostatic hyperplasia: a randomized study. BJU Int. 1999;84:292\u2013296. https:\/\/doi.org\/10.1046\/j.1464-410x.1999.00234.x","DOI":"10.1046\/j.1464-410x.1999.00234.x"},{"key":"98353","doi-asserted-by":"crossref","unstructured":"Francisca EA, d\u2019Ancona FC, Hendriks JC, et al. Quality of life assessment in patients treated with lower energy thermotherapy (Prostasoft 2.0): results of a randomized transurethral microwave thermotherapy versus sham study. J Urol. 1997;158:1839\u20131844. https:\/\/doi.org\/10.1016\/s0022-5347(01)64141-7","DOI":"10.1016\/S0022-5347(01)64141-7"},{"key":"98354","doi-asserted-by":"crossref","unstructured":"Blute ML, Patterson DE, Segura JW, et al. Transurethral microwave thermotherapy v sham treatment: double-blind randomized study. J Endourol. 1996;10:565\u2013573. https:\/\/doi.org\/10.1089\/end.1996.10.565","DOI":"10.1089\/end.1996.10.565"},{"key":"98355","doi-asserted-by":"crossref","unstructured":"Nawrocki JD, Bell TJ, Lawrence WT, et al. A randomized controlled trial of transurethral microwave thermotherapy. Br J Urol. 1997;79:389\u2013393. https:\/\/doi.org\/10.1046\/j.1464-410x.1997.21515.x","DOI":"10.1046\/j.1464-410X.1997.21515.x"},{"key":"98356","doi-asserted-by":"crossref","unstructured":"Roehrborn CG, Preminger G, Newhall P, et al. Microwave thermotherapy for benign prostatic hyperplasia with the Dornier Urowave: results of a randomized, double-blind, multicenter, sham-controlled trial. Urology. 1998;51:19\u201328. https:\/\/doi.org\/10.1016\/s0090-4295(97)00571-2","DOI":"10.1016\/S0090-4295(97)00571-2"},{"key":"98357","doi-asserted-by":"crossref","unstructured":"Albala DM, Fulmer BR, Turk TMT, et al. Office-based transurethral microwave thermotherapy using the TherMatrx TMx-2000. J Endourol. 2002;16:57\u201361. https:\/\/doi.org\/10.1089\/089277902753483745","DOI":"10.1089\/089277902753483745"},{"key":"98358","doi-asserted-by":"crossref","unstructured":"Ogden CW, Reddy P, Johnson H, et al. 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