{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:34:52Z","timestamp":1783463692903,"version":"3.55.0"},"reference-count":58,"publisher":"MJS Publishing, Medical Journals Sweden AB","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SJU"],"abstract":"<jats:p>Objective: To investigate histopathological assessment practices following medical circumcision, analyse the prevalence of lichen sclerosus (LS) and assess the management of circumcised LS patients.\nMaterial and methods: This retrospective study was conducted at Ume\u00e5 University Hospital. A total of 416 patients aged \u226518 years who underwent medical circumcision between 2016 and 2023 were included. The variables investigated were the frequency of histopathological diagnosis of preputial tissue, pre- and post-surgery treatment, further management and the prevalence of LS.\nResults: The mean (standard deviation [SD]) age of included patients was 47 (21) years. Before circumcision, 34% (141\/416) of the study population had received treatment with potent or ultrapotent topical corticosteroids. A pre-operative diagnosis of LS was set in 4.8% (20\/416) of the patients. Histopathological analysis of circumcised material was performed in 44% (183\/416) of cases. Amongst these, LS was confirmed in 60% (110\/183). Amongst the patients with histologically confirmed LS, 13% (14\/110) received a recorded diagnosis of LS. A total of 15% (16\/110) of the patients with LS were either referred to a dermatovenereologist and\/or received treatment with an ultrapotent topical corticosteroid.\nConclusions: LS appears to be both underdiagnosed and not adequately treated in patients undergoing medical circumcision. Less than half of the circumcised specimens were analysed, which means a risk of missing LS and potential dysplastic changes. Most patients with LS did not receive adequate diagnosis and treatment after surgery. Failure to diagnose LS limits patient awareness, follow-up and appropriate care, factors that may contribute to disease progression and increased cancer risk.<\/jats:p>","DOI":"10.2340\/sju.v61.45886","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T11:30:44Z","timestamp":1777289444000},"page":"156-162","source":"Crossref","is-referenced-by-count":1,"title":["Histopathological assessment practices in adult male circumcision and detection of lichen sclerosus: a retrospective single-centre study"],"prefix":"10.2340","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6961-3777","authenticated-orcid":false,"given":"Jenny","family":"Engman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6106-0174","authenticated-orcid":false,"given":"Wilma","family":"H\u00e5kansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7682-4565","authenticated-orcid":false,"given":"Nirina","family":"Andersson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8601-0159","authenticated-orcid":false,"given":"Johan","family":"Svensson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6009-6911","authenticated-orcid":false,"given":"Elisabet","family":"Nylander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3675-3050","authenticated-orcid":false,"given":"Amir","family":"Sherif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9976-5702","authenticated-orcid":false,"given":"Maja","family":"Af Klinteberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1183","published-online":{"date-parts":[[2026,4,27]]},"reference":[{"key":"152762","doi-asserted-by":"crossref","unstructured":"Powell JJ, Wojnarowska F. 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