{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T16:36:09Z","timestamp":1755794169934,"version":"3.44.0"},"reference-count":29,"publisher":"Operative Dentistry","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,1,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>This study evaluated, histopathologically, the pulpal and periapical response to a silorane-based resin (Filtek Silorane) and a methacrylate-based nanoparticle resin (Filtek Supreme XT) in deep cavities in dogs, having zinc oxide and eugenol-based cement (ZOE) as a control.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>The tooth\/bone blocks were collected after 10 and 90 days and processed for microscopic analysis of the dentin, pulp, and periapical tissues using a score system. Data were analyzed statistically by Kruskal-Wallis and Dunn post-test (\u03b1=0.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>At 10 days, the pulp, connective tissue, and periodontal ligament showed normal characteristics. No resorption areas were observed. Both resins caused significantly less (p&amp;lt;0.05) periapical and pulpal inflammatory response than ZOE. At 90 days, for all materials, the connective pulp tissue was healthy and dense, with a normal blood vessel system. The apical and periapical region had normal structure and thickness.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions:<\/jats:title>\n                  <jats:p>The use of the Filtek Silorane and the Filtek Supreme XT resins caused no adverse pulpal and periapical reactions after restoration of deep dentin cavities in vivo.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2341\/11-341-l","type":"journal-article","created":{"date-parts":[[2012,7,7]],"date-time":"2012-07-07T21:29:28Z","timestamp":1341696568000},"page":"73-81","source":"Crossref","is-referenced-by-count":4,"title":["Pulpal and Periapical Response After Restoration of Deep Cavities in Dogs' Teeth With Filtek Silorane and Filtek Supreme XT Systems"],"prefix":"10.2341","volume":"38","author":[{"given":"E","family":"Ruiz-de-Casta\u00f1eda","sequence":"first","affiliation":[{"name":"Esther Ruiz-de-Casta\u00f1eda, MS, Catalan Society of Dentistry and Stomatology, Academy of Medical Sciences and Health of Catalonia and Balears, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Gat\u00f3n-Hern\u00e1ndez","sequence":"first","affiliation":[{"name":"Patricia Gat\u00f3n-Hern\u00e1ndez, PhD, School of Dentistry, University of Barcelona, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"EG","family":"Rodriguez","sequence":"first","affiliation":[{"name":"Encarnaci\u00f3n G. Rodriguez, PhD, School of Dentistry, University of Granada, Granada, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RAB","family":"Silva","sequence":"first","affiliation":[{"name":"Raquel A.B. Silva, PhD, School of Dentistry of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Department of Pediatric Clinic, Preventive and Community Dentistry, Ribeir\u00e3o Preto, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Nelson-Filho","sequence":"first","affiliation":[{"name":"Paulo Nelson-Filho, PhD, School of Dentistry of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Department of Pediatric Clinic, Preventive and Community Dentistry, Ribeir\u00e3o Preto, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LAB","family":"Silva","sequence":"first","affiliation":[{"name":"Raquel A.B. 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