{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T03:37:32Z","timestamp":1790048252064,"version":"4.0.1"},"reference-count":51,"publisher":"Operative Dentistry","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,9,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n               <jats:p>This study evaluated the effects of simulated hydrostatic pulpal pressure (SPP) on the microtensile bond strength (\u03bcTBS) to dentin and nanoleakage patterns produced by self-adhesive luting agents after 12 months. Three self-adhesive luting agents (RelyX Unicem [UN], RelyX U100 [UC], and Clearfil SA Luting [SA]) and three conventional luting agents (Rely X ARC [RX], Panavia F [PF], and a two-step self-etching adhesive system [Clearfil SE Bond] associated with Panavia F [PS]) were evaluated. One hundred twenty-three human molars were abraded to expose occlusal surfaces. Resin cements were used to lute cylindrical composite blocks to the teeth either subjected or not to SPP. Sixty specimens were subjected to 15 cm H2O of SPP for 24 hours before and 24 hours or 12 months after cementation procedures. Afterward, restored teeth were serially sectioned into beams with a cross-sectional area of 1 mm2 at the bonded interface and were tested in tension (cross-head speed of 1 mm\/min). Failure mode was determined using scanning electron microscopy (SEM). Data were statistically analyzed by three-way analysis of variance and post hoc Tukey test (p=0.05). Two additional teeth in each group were serially sectioned into 0.9-mm-thick slabs, which were submitted to a nanoleakage protocol with AgNO3 and analyzed with scanning and transmission electron microscopes. The \u03bcTBS values of the etch-and-rinse group (RX) were negatively influenced by SPP and long-term water storage with SPP. After 12 months, UC and SA presented premature failures in all specimens when submitted to SPP. SPP increased silver deposition in most groups in both evaluation times. The hydrostatic pulpal pressure effect was material dependent. The storage time without SPP did not affect bond strength. However, long-term SPP influenced the performance of the etch-and-rinse and self-adhesive cements regarding \u03bcTBS and nanoleakage pattern, except to UN.<\/jats:p>","DOI":"10.2341\/13-078","type":"journal-article","created":{"date-parts":[[2014,2,6]],"date-time":"2014-02-06T15:27:42Z","timestamp":1391700462000},"page":"508-520","source":"Crossref","is-referenced-by-count":8,"title":["Effect of Long-term Simulated Pulpal Pressure on the Bond Strength and Nanoleakage of Resin-luting Agents With Different Bonding Strategies"],"prefix":"10.2341","volume":"39","author":[{"given":"RS","family":"de Alexandre","sequence":"first","affiliation":[{"name":"Rodrigo Sversut de Alexandre, DDS, MS, PhD, University of Guarulhos, Department of Operative Dentistry and University of North S\u00e3o Paulo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"VB","family":"Santana","sequence":"first","affiliation":[{"name":"Ver\u00f4nica Batista Santana, DDS, MS, University of Guarulhos, Department of Operative Dentistry, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AC","family":"Kasaz","sequence":"first","affiliation":[{"name":"Alline C Kasaz, DDS, MS, University of Guarulhos, Operative Dentistry, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CAG","family":"Arrais","sequence":"first","affiliation":[{"name":"Cesar AG Arrais, DDS, MS, PhD, Ponta Grossa State University, Department of Operative Dentistry, Parana, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JA","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Jos\u00e9 Augusto Rodrigues, DDS, MS, PhD, University of Guarulhos, Department of Operative Dentistry, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AF","family":"Reis","sequence":"first","affiliation":[{"name":"Andre F Reis, DDS, MS, PhD, University of Guarulhos, Department of Operative Dentistry, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1188","reference":[{"issue":"2","key":"2020060414455670000_i1559-2863-39-5-508-b01","first-page":"185","article-title":"Curing depth of a resin-modified glass ionomer and two resin-based luting agents","volume":"30","author":"Sigemori","year":"2005","journal-title":"Operative Dentistry"},{"issue":"1","key":"2020060414455670000_i1559-2863-39-5-508-b02","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jdent.2003.08.003","article-title":"Adhesive permeability affects coupling of resin cements that utilise self-etching primers to dentine","volume":"32","author":"Carvalho","year":"2004","journal-title":"Journal of Dentistry"},{"issue":"4","key":"2020060414455670000_i1559-2863-39-5-508-b03","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0099-2399(06)80564-9","article-title":"Dentinal fluid dynamics in human teeth","volume":"21","author":"Ciucchi","year":"1995","journal-title":"in vivo Journal of Endodontics"},{"issue":"1","key":"2020060414455670000_i1559-2863-39-5-508-b04","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/jbm.b.10560","article-title":"SEM and TEM analysis of water degradation of human dentinal collagen","volume":"66","author":"Hashimoto","year":"2003","journal-title":"Journal of Biomedical Materials Research. 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Single-step self-etching adhesive","volume":"5","author":"Tay","year":"2003","journal-title":"Journal of Adhesive Dentistry"},{"issue":"8","key":"2020060414455670000_i1559-2863-39-5-508-b41","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0109-5641(02)00005-2","article-title":"Micro-tensile bond testing of resin cements to dentin and an indirect resin composite","volume":"18","author":"Mak","year":"2002","journal-title":"Dental Materials"},{"issue":"7","key":"2020060414455670000_i1559-2863-39-5-508-b42","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1177\/154405910508400714","article-title":"Water concentration in self-etching primers affects their aggressiveness and bonding efficacy to dentin","volume":"84","author":"Hiraishi","year":"2005","journal-title":"Journal of Dental Research"},{"issue":"6","key":"2020060414455670000_i1559-2863-39-5-508-b43","first-page":"733","article-title":"Microtensile dentin bond strength of self-etching resins: effect of a hydrophobic layer","volume":"30","author":"Brackett","year":"2005","journal-title":"Operative Dentistry"},{"issue":"2","key":"2020060414455670000_i1559-2863-39-5-508-b44","first-page":"126","article-title":"Conversion of one-step to two-step self-etch adhesives for improved efficacy and extended application","volume":"18","author":"King","year":"2005","journal-title":"American Journal of Dentistry"},{"issue":"2","key":"2020060414455670000_i1559-2863-39-5-508-b45","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/jbm.b.30795","article-title":"Adhesive performance of dentin bonding agents applied in vivo and in vitro: effect of intrapulpal pressure and dentin depth","volume":"83","author":"Hebling","year":"2007","journal-title":"Journal of Biomedical Materials Research. 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