{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:14:20Z","timestamp":1771467260514,"version":"3.50.1"},"reference-count":39,"publisher":"Operative Dentistry","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n        <jats:sec>\n          <jats:title>Objectives<\/jats:title>\n          <jats:p>To explore the ferrule effect on Resin Nano-Ceramic (RNC) premolar endocrown marginal integrity and fracture resistance.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Methods<\/jats:title>\n          <jats:p>Thirty-six root\u2013canal-treated premolars were cut 2 mm above the cemento-enamel junction (CEJ). They were restored with standardized RNC computer-aided design\/computer-aided manufacturing (CAD\/CAM) restorations (Lava Ultimate, 3M Oral Care, St. Paul, MN, USA) and divided into three groups (n=12): endocrowns with a 3-mm endo-core (Group 1), endocrowns with a 3-mm endo-core and a 2-mm ferrule (Group 2), and conventional post-and-core crowns with a 2-mm ferrule (Group 3). All specimens were submitted to thermo-mechanical cycling loading (TMCL) (1.7 Hz, 49 N, 600 000 cycles, 1500 thermocycles). Margins were analyzed before and after the TMCL. In the second part of the experiment, the surviving specimens were submitted to unidirectional monotonic loading until fracture. Fragments were then analyzed using scanning electron microscopy (SEM) and the fracture mode was established.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Results<\/jats:title>\n          <jats:p>Endocrowns of Groups 1 and 2 performed better than conventional crowns (Group 3) in terms of marginal continuity. Differences in fracture load values within all groups were not statistically significant. Most of the specimens fractured in a non-repairable way.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Conclusions<\/jats:title>\n          <jats:p>The present test failed to provide evidence of any kind of difference between endocrowns with and without a ferrule in terms of load-bearing capacity and marginal integrity after fatigue. Further studies are needed to confirm the role of the ferrule in adhesive restorations of endodontically treated teeth.<\/jats:p>\n        <\/jats:sec>","DOI":"10.2341\/20-081-l","type":"journal-article","created":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T16:01:30Z","timestamp":1651680090000},"page":"650-660","source":"Crossref","is-referenced-by-count":4,"title":["Restoration of Severely Damaged Endodontically Treated Premolars: Influence of the Ferrule Effect on Marginal Integrity and Fracture Load of Resin Nano-ceramic CAD-CAM Endocrowns"],"prefix":"10.2341","volume":"46","author":[{"given":"GT","family":"Rocca","sequence":"first","affiliation":[{"name":"*Giovanni Tommaso Rocca, Department of Cariology and Endodontics, School of Dentistry, University of Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JJ","family":"Canneto","sequence":"additional","affiliation":[{"name":"Jean Jacques Canneto, DMD, Department of Cariology and Endodontics, School of Dentistry, University of Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Scotti","sequence":"additional","affiliation":[{"name":"Nicola Scotti, DMD, Department of Cariology and Operative Dentistry, School of Dentistry, University of Turin, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Daher","sequence":"additional","affiliation":[{"name":"Rene Daher, DMD, Department of Cariology and Endodontics, School of Dentistry, University of Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Feilzer","sequence":"additional","affiliation":[{"name":"Albert Feilzer, professor, Department of Dental Materials, Academisch Centrum Tandheelkunde Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CM","family":"Saratti","sequence":"additional","affiliation":[{"name":"Carlo Massimo Saratti, DMD, Department of Cariology and Endodontics, School of Dentistry, University of Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Krejci","sequence":"additional","affiliation":[{"name":"Ivo Krejci, Professor, Department of Cariology and Endodontics, School of Dentistry, University of Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1188","reference":[{"issue":"4","key":"i1559-2863-46-6-650-b1","series-title":"Journal of Dentistry","first-page":"312","article-title":"Effect of fibre post length and text adhesive strategy on fracture resistance of endodontically treated teeth after fatigue loading","volume":"40","year":"2012","unstructured":"Zicari\n              F,\n            \n            \n              Van Meerbeek\n              B,\n            \n            \n              Scotti\n              R,\n             &\n\t\t\t\t\t\tNaertI (\n\t\t\t\t\t2012)\n\t\t\t\t\tEffect of fibre post length and text adhesive 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    \n              Lohbauer\n              U,\n            \n            \n              Nikolaenko\n              SA,\n             &\n\t\t\t\t\t\tReichSM (\n\t\t\t\t\t2007)\n\t\t\t\t\tMarginal integrity: Is the clinical performance of bonded restorations predictable in vitro?Journal of Adhesive Dentistry9 (\n\t\t\t\t\tSupplement 1)\n\t\t\t\t\t107\u2013\n\t\t\t\t\t116."},{"issue":"1","key":"i1559-2863-46-6-650-b30","series-title":"Dental Materials","first-page":"59","article-title":"Clinical relevance of tests on bond strength, microleakage and marginal adaptation","volume":"29","year":"2013","unstructured":"Heintze\n              SD\n            \n           (\n\t\t\t\t\t2013)\n\t\t\t\t\tClinical relevance of tests on bond strength, microleakage and marginal adaptationDental Materials29(\n\t\t\t\t\t1)\n\t\t\t\t\t59\u2013\n\t\t\t\t\t84."},{"issue":"6","key":"i1559-2863-46-6-650-b31","series-title":"Operative Dentistry","first-page":"663","article-title":"Composite vs ceramic computer-aided design\/computer-assisted manufacturing crowns in endodontically treated teeth: analysis of marginal adaptation","volume":"38","year":"2013","unstructured":"Ram\u00edrez-Sebasti\u00e0\n              A,\n            \n            \n              Bortolotto\n              T,\n            \n            \n              Roig\n              M,\n             &\n\t\t\t\t\t\tKrejciI (\n\t\t\t\t\t2013)\n\t\t\t\t\tComposite vs ceramic computer-aided design\/computer-assisted manufacturing crowns in endodontically treated teeth: analysis of marginal adaptationOperative Dentistry38(\n\t\t\t\t\t6)\n\t\t\t\t\t663\u2013\n\t\t\t\t\t673."},{"issue":"9","key":"i1559-2863-46-6-650-b32","series-title":"Dental Materials","first-page":"954","article-title":"The fracture resistance of a CAD\/CAM Resin Nano Ceramic (RNC) and a CAD ceramic at different thicknesses","volume":"30","year":"2014","unstructured":"Chen\n              C,\n            \n            \n              Trindade\n              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design on the fatigue resistance of endodontically treated molars restored with resin nanoceramic CAD\/CAM crownsOperative Dentistry39(\n\t\t\t\t\t6)\n\t\t\t\t\t595\u2013\n\t\t\t\t\t602."},{"issue":"4","key":"i1559-2863-46-6-650-b35","series-title":"Journal of Prosthetic Dentistry","first-page":"574","article-title":"Fatigue resistance of ultrathin CAD\/CAM complete crowns with a simplified cementation process","volume":"114","year":"2015","unstructured":"Magne\n              P,\n            \n            \n              Carvalho\n              AO,\n            \n            \n              Bruzi\n              G,\n             &\n\t\t\t\t\t\tGianniniM (\n\t\t\t\t\t2015)\n\t\t\t\t\tFatigue resistance of ultrathin CAD\/CAM complete crowns with a simplified cementation processJournal of Prosthetic Dentistry114(\n\t\t\t\t\t4)\n\t\t\t\t\t574\u2013\n\t\t\t\t\t579."},{"issue":"4","key":"i1559-2863-46-6-650-b36","series-title":"Journal of Prosthetic 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      Janal\n              MN,\n            \n            \n              Thompson\n              VP,\n            \n            \n              Opdam\n              NJ,\n             &\n\t\t\t\t\t\tZangY (\n\t\t\t\t\t2016)\n\t\t\t\t\tFatigue resistance of CAD\/CAM resin composite molar crownsDental Materials32(\n\t\t\t\t\t4)\n\t\t\t\t\t499\u2013\n\t\t\t\t\t509."},{"issue":"6","key":"i1559-2863-46-6-650-b38","series-title":"Clinical Oral Investigations","first-page":"2777","article-title":"Fracture load of CAD\/CAM-fabricated and 3D-printed composite crowns as a function of material thickness","volume":"23","year":"2019","unstructured":"Zimmermann\n              M,\n            \n            \n              Ender\n              A,\n            \n            \n              Egli\n              G,\n            \n            \n              \u00d6zcan\n              M,\n             &\n\t\t\t\t\t\tMehlA (\n\t\t\t\t\t2019)\n\t\t\t\t\tFracture load of CAD\/CAM-fabricated and 3D-printed 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