{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T23:30:26Z","timestamp":1785367826052,"version":"3.55.0"},"reference-count":39,"publisher":"Operative Dentistry","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n        <jats:p>Maxillary lateral incisor agenesis (MLIA) is a condition that significantly compromises smile esthetics and is a particular concern in younger patients. The treatment options include orthodontics for space opening with rehabilitation or space closure with canine camouflage. Currently, there is some controversy regarding the most appropriate treatment. In this case report, we propose a multidisciplinary approach through the combination of orthodontic treatment, frenectomy, and a restorative finishing stage with composite resin and dental implants. More specifically, this treatment was planned to orthodontically close the anterior space by opening the premolar area for subsequent placement of implants and enameloplasty with a composite resin.<\/jats:p>\n        <jats:p>The replacement of a missing lateral incisor by an implant is a predictable treatment approach, but it might best be deferred until dental maturity and then accurately placed in a well-developed site through a multidisciplinary approach. Precluding the closure of the anterior spaces and the opening of the posterior zone for implant placement, allows for a more stable and appealing esthetic and functional rehabilitation for young patients, in whom esthetic appearance and self-esteem play a primary role.<\/jats:p>","DOI":"10.2341\/21-069-s","type":"journal-article","created":{"date-parts":[[2022,8,24]],"date-time":"2022-08-24T14:39:21Z","timestamp":1661351961000},"page":"367-374","source":"Crossref","is-referenced-by-count":4,"title":["A Multidisciplinary Approach to Maxillary Lateral Incisor Agenesis (MLIA): A Case Report"],"prefix":"10.2341","volume":"47","author":[{"given":"L","family":"Lopes-Rocha","sequence":"first","affiliation":[{"name":"L\u00edgia Lopes-Rocha, DDS, UNIPRO, Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), CESPU, Gandra Campus, Paredes, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Rocha","sequence":"additional","affiliation":[{"name":"Duarte Rocha, DDS, UNIPRO, Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), CESPU, Gandra Campus, Paredes, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Pinho","sequence":"additional","affiliation":[{"name":"*Teresa Pinho, DDS, PhD, UNIPRO, Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), CESPU, Gandra Campus, Paredes, Portugal. IBMC - Institute of Molecular and Cellular Biology, i3S - Institute of Innovation and Research in Health, Oporto University, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1188","reference":[{"issue":"3","key":"i1559-2863-47-4-367b-b1","series-title":"Community Dentistry and Oral Epidemiology","first-page":"217","article-title":"A meta-analysis of the prevalence of dental agenesis of permanent teeth","volume":"32","year":"2004","unstructured":"Polder\n              B,\n            \n            \n              Van\u2019t Hof\n              M,\n            \n            \n              Van Der Linden\n              F,\n             &\n\t\t\t\t\t\tKuijpers-JagtmanA(\n\t\t\t\t\t2004)\n\t\t\t\t\tA meta-analysis of the prevalence of dental agenesis of permanent teethCommunity Dentistry and Oral Epidemiology32(\n\t\t\t\t\t3)\n\t\t\t\t\t217\u2013\n\t\t\t\t\t226."},{"issue":"5","key":"i1559-2863-47-4-367b-b2","series-title":"European Journal of Orthodontics","first-page":"443","article-title":"Developmental absence of maxillary lateral incisors in the Portuguese population","volume":"27","year":"2005","unstructured":"Pinho\n              T,\n            \n            \n              Tavares\n              P,\n            \n            \n              Maciel\n              P,\n             &\n\t\t\t\t\t\tPollmannC(\n\t\t\t\t\t2005)\n\t\t\t\t\tDevelopmental absence of maxillary lateral incisors in the Portuguese populationEuropean Journal of Orthodontics27(\n\t\t\t\t\t5)\n\t\t\t\t\t443\u2013\n\t\t\t\t\t449."},{"issue":"4","key":"i1559-2863-47-4-367b-b3","series-title":"Journal of Clinical Pediatric Dentistry","first-page":"244","article-title":"Agenesis of the permanent lateral incisor: Distribution, number and sites","volume":"15","year":"1991","unstructured":"Stamatiou\n              J\n             &\n\t\t\t\t\t\tSymonsAL(\n\t\t\t\t\t1991)\n\t\t\t\t\tAgenesis of the permanent lateral incisor: Distribution, number and sitesJournal of Clinical Pediatric Dentistry -\n\t\t\t\t\t15(\n\t\t\t\t\t4)\n\t\t\t\t\t244\u2013\n\t\t\t\t\t246."},{"issue":"4","key":"i1559-2863-47-4-367b-b4","series-title":"World Journal of Orthodontics","first-page":"376","article-title":"Diagnostic protocol in cases of congenitally missing maxillary lateral incisors","volume":"7","year":"2006","unstructured":"Ara\u00fajo\n              EA,\n            \n            \n              Oliveira\n              DD,\n             &\n\t\t\t\t\t\tAra\u00fajoMT(\n\t\t\t\t\t2006)\n\t\t\t\t\tDiagnostic protocol in cases of congenitally missing maxillary lateral incisorsWorld Journal of Orthodontics7(\n\t\t\t\t\t4)\n\t\t\t\t\t376\u2013\n\t\t\t\t\t388."},{"issue":"5","key":"i1559-2863-47-4-367b-b5","series-title":"British Dental Journal","first-page":"245","article-title":"The interdisciplinary management of hypodontia: Background and role of paediatric dentistry","volume":"194","year":"2003","unstructured":"Nunn\n              JH,\n            \n            \n              Carter\n              NE,\n            \n            \n              Gillgrass\n              TJ,\n            \n            \n              Hobson\n              RS,\n            \n            \n              Jepson\n              NJ,\n            \n            \n              Meechan\n              JG,\n             &\n\t\t\t\t\t\tNohlFS(\n\t\t\t\t\t2003)\n\t\t\t\t\tThe interdisciplinary management of hypodontia: Background and role of paediatric dentistryBritish Dental Journal194(\n\t\t\t\t\t5)\n\t\t\t\t\t245\u2013\n\t\t\t\t\t251.6."},{"issue":"1","key":"i1559-2863-47-4-367b-b6","series-title":"Journal of Esthetic and Restorative Dentistry","first-page":"5","article-title":"Managing congenitally missing lateral incisors. 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Dentistry","first-page":"597","article-title":"The effect of elapsed time following bleaching on enamel bond strength of resin composite","volume":"26","year":"2001","unstructured":"Cavalli\n              V,\n            \n            \n              Reis\n              AF,\n            \n            \n              Giannini\n              M,\n             &\n\t\t\t\t\t\tAmbrosanoGM(\n\t\t\t\t\t2001)\n\t\t\t\t\tThe effect of elapsed time following bleaching on enamel bond strength of resin compositeOperative Dentistry26(\n\t\t\t\t\t6)\n\t\t\t\t\t597\u2013\n\t\t\t\t\t602."},{"issue":"1","key":"i1559-2863-47-4-367b-b35","series-title":"European Journal of Esthetic Dentistry","first-page":"102","article-title":"Composite in everyday practice: How to choose the right material and simplify application techniques in the anterior teeth","volume":"5","year":"2010","unstructured":"Devoto\n              W,\n            \n            \n              Saracinelli\n              M,\n             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Dentistry23(\n\t\t\t\t\t6)\n\t\t\t\t\t543\u2013\n\t\t\t\t\t555."},{"issue":"4","key":"i1559-2863-47-4-367b-b39","series-title":"Journal of Esthetic and Restorative Dentistry","first-page":"252","article-title":"Morphologic texture characterization allied to cigarette smoke increase pigmentation in composite resin restorations","volume":"22","year":"2010","unstructured":"Mathias\n              P,\n            \n            \n              Costa\n              L,\n            \n            \n              Saraiva\n              LO,\n            \n            \n              Rossi\n              TA,\n            \n            \n              Cavalcanti\n              AN,\n             &\n\t\t\t\t\t\tDa Rocha Nogueira-FilhoG(\n\t\t\t\t\t2010)\n\t\t\t\t\tMorphologic texture characterization allied to cigarette smoke increase pigmentation in composite resin restorationsJournal of Esthetic and Restorative 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