{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:23:57Z","timestamp":1791332637896,"version":"4.3.1"},"reference-count":63,"publisher":"Operative Dentistry","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n        <jats:sec>\n          <jats:title>Purpose<\/jats:title>\n          <jats:p>The purpose of this study was to evaluate the leaching pattern of different types of polymer computer-aided design and computer-aided manufacturing (CAD-CAM) materials with a conventional resin composite.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Methods and Materials<\/jats:title>\n          <jats:p>Specimens of three representatives by type of polymer CAD-CAM blocks and one conventional resin composite were suspended using a silk thread in distilled water and artificial saliva. After one day, seven days, 14 days, 30 days, and 60 days, the analysis of the eluates for the detection of bisphenol A (BPA), urethane dimethacrylate (UDMA), triethylene glycol dimethacrylate (TEGDMA) and bisphenol A-glycidyl dimethacrylate (Bis-GMA) was quantified by utilizing high-performance liquid chromatography (HPLC).<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Results<\/jats:title>\n          <jats:p>TEGDMA was the main eluted monomer for the polymer CAD-CAM materials for both solutions. However, there was a decreasing pattern throughout the tested period. On the contrary, there was a constant release of monomers from the conventional resin composite. Bisphenol-A was released only by the conventional resin composite and in both solutions chosen.<\/jats:p>\n        <\/jats:sec>\n        <jats:sec>\n          <jats:title>Conclusions<\/jats:title>\n          <jats:p>Different types of polymer CAD-CAM materials release minimal or no monomers compared to the conventional resin composite material. The methods of fabrication of polymer CAD-CAM materials produces better properties than the conventional resin composite with a dramatic decrease of monomer elution.<\/jats:p>\n        <\/jats:sec>","DOI":"10.2341\/21-079-l","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T15:38:50Z","timestamp":1661528330000},"page":"E241-E252","source":"Crossref","is-referenced-by-count":5,"title":["Elution of Monomers From CAD-CAM Materials and Conventional Resin Composite in Distilled Water and Artificial Saliva"],"prefix":"10.2341","volume":"47","author":[{"given":"P","family":"Mourouzis","sequence":"first","affiliation":[{"name":"*Petros Mourouzis, MSc, PhD, assistant professor, Department of Operative Dentistry, Division of Dental Tissues Pathology and Therapeutics, Faculty of Dentistry, Aristotle University of Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E-I","family":"Diamantopoulou","sequence":"additional","affiliation":[{"name":"Ellisavet-Ioanna Diamantopoulou, MSc, Department of Chemistry, Laboratory of Analytical Chemistry, Aristotle University of Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Plastiras","sequence":"additional","affiliation":[{"name":"Orfeas Plastiras, MSc, Department of Chemistry, Laboratory of Analytical Chemistry, Aristotle University of Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Samanidou","sequence":"additional","affiliation":[{"name":"Victoria Samanidou, PhD, professor, Department of Chemistry, Laboratory of Analytical Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Tolidis","sequence":"additional","affiliation":[{"name":"Kosmas 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