{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:32:20Z","timestamp":1784129540288,"version":"3.55.0"},"reference-count":24,"publisher":"Operative Dentistry","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n        <jats:p>The patient underwent combined orthodonticorthognathic surgical treatment due to her skeletal Class III malocclusion. In the first phase, orthodontic decompensation was performed with maxillary and mandibular fixed appliances. The maxillary first premolars were extracted; the created space was closed by anterior retraction. The posterior anchorage was reinforced with interradicular temporary anchorage devices. In the second phase, a digital surgical treatment plan was made with intra- and extraoral simulation (including occlusion and profile). During the orthognathic surgery, a bilateral sagittal split osteotomy with mandibular setback was combined with maxillary movements, using 3D-printed surgical splints. In the third phase, the orthodontic treatment continued to finish and settle the occlusion. Spaces were created between the upper incisors for ceramic veneers to gain proper overjet and occlusion. The last phase was prosthetic and esthetic rehabilitation. During the planning, a 2Dand 3D-smile design was created and presented to the patient as a mock-up. After digital impression and design, four E-max veneers were milled and cemented using dual cement to finish the workflow. Retention splints were created to preserve the new status as a final step.<\/jats:p>","DOI":"10.2341\/23-099-s","type":"journal-article","created":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T16:04:05Z","timestamp":1744041845000},"page":"123-131","source":"Crossref","is-referenced-by-count":4,"title":["Combined Orthodontic, Orthognathic Surgical, and Prosthodontic Treatment for Severe Class III Malocclusion Using Digital Workflows"],"prefix":"10.2341","volume":"50","author":[{"given":"L","family":"Szegedi","sequence":"first","affiliation":[{"name":"Levente Szegedi, DMD, Department of Pediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"NK","family":"R\u00f3zsa","sequence":"additional","affiliation":[{"name":"No\u00e9mi Katinka R\u00f3zsa, DMD, Department of Pediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Nemes","sequence":"additional","affiliation":[{"name":"B\u00e1lint Nemes, DMD, Department of Pediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"L\u0151rincz","sequence":"additional","affiliation":[{"name":"Gergely L\u0151rincz, DMD, Department of Pediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Kreuter","sequence":"additional","affiliation":[{"name":"Patrik Kreuter, DMD, Department of Pediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"V\u00e9gh","sequence":"additional","affiliation":[{"name":"D\u00e1niel V\u00e9gh, DMD, Department of Prosthodontics, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"R\u00f3th","sequence":"additional","affiliation":[{"name":"Ivett R\u00f3th, DMD, Department of Prosthodontics, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Bogd\u00e1n","sequence":"additional","affiliation":[{"name":"S\u00e1ndor Bogd\u00e1n, DMD, Department of Oro-Maxillofacial Surgery and Stomatology, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Hermann","sequence":"additional","affiliation":[{"name":"P\u00e9ter Hermann, DMD, Department of Prosthodontics, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z","family":"G\u00e9czi","sequence":"additional","affiliation":[{"name":"*Zolt\u00e1n G\u00e9czi, DMD, PhD, Department of Prosthodontics, Semmelweis University, Budapest, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1188","reference":[{"issue":"9","key":"b1","series-title":"British Dental Journal","first-page":"505","article-title":"Digital dentistry: An overview of recent developments for CAD\/CAM generated restorations","volume":"204","author":"Beuer\n              F","year":"2008","unstructured":"Beuer\n              F\n            , SchweigerJ, & EdelhoffD (2008) Digital dentistry: An overview of recent developments for CAD\/CAM generated restorationsBritish Dental Journal204(9) 505-511. doi:10.1038\/sj.bdj.2008.350"},{"issue":"1","key":"b2","series-title":"Maxillofacial Plastic and Reconstructive Surgery","first-page":"2","article-title":"Comparison of feasibility, time consumption and costs of three virtual planning systems for surgical correction of midfacial deficiency","volume":"43","author":"Willinger\n              K","year":"2021","unstructured":"Willinger\n              K\n            , Guevara-RojasG, CedeJ, SchichoK, StammT, KlugC (2021) Comparison of feasibility, time consumption and costs of three virtual planning systems for surgical correction of midfacial deficiencyMaxillofacial Plastic and Reconstructive Surgery43(1) 2. doi:10.1186\/s40902-020-00284-1"},{"issue":"2","key":"b3","series-title":"Orthodontics and Craniofacial Research","first-page":"69","article-title":"Genes, genetics, and Class III malocclusion","volume":"13","author":"Xue\n              F","year":"2010","unstructured":"Xue\n              F\n            , WongRW, RabieAB (2010) Genes, genetics, and Class III malocclusionOrthodontics and Craniofacial Research13(2) 69-74. doi:10.1111\/j.1601-6343.2010.01485.x"},{"issue":"1","key":"b4","series-title":"Progress in Orthodontics","first-page":"40","article-title":"A novel method for treatment of Class III malocclusion in growing patients","volume":"18","author":"Al-Mozany\n              SA","year":"2017","unstructured":"Al-Mozany\n              SA\n            , DalciO, AlmuzianM, GonzalezC, TarrafNE, Ali DarendelilerM (2017) A novel method for treatment of Class III malocclusion in growing patientsProgress in Orthodontics18(1) 40. doi:10.1186\/s40510-017-0192-y"},{"issue":"6","key":"b5","series-title":"Journal of Craniofacial Surgery","first-page":"1816","article-title":"Physical versus digital orthognathic surgical planning","volume":"33","author":"Ghanem\n              AA","year":"2022","unstructured":"Ghanem\n              AA\n            , HamadOA, AlmukhtarAM, & SleemHA (2022) Physical versus digital orthognathic surgical planningJournal of Craniofacial Surgery33(6) 1816-1819. doi:10.1097\/SCS.0000000000008462"},{"issue":"10","key":"b6","series-title":"Journal of Oral and Maxillofacial Surgery","first-page":"1128","article-title":"Incidence of complications and problems related to orthognathic surgery: A review of 655 patients","volume":"59","author":"Panula\n              K","year":"2001","unstructured":"Panula\n              K\n            , FinneK, & OikarinenK (2001) Incidence of complications and problems related to orthognathic surgery: A review of 655 patientsJournal of Oral and Maxillofacial Surgery59(10) 1128-1137. doi:10.1053\/joms.2001.26704"},{"issue":"4","key":"b7","series-title":"Journal of Prosthetic Dentistry","first-page":"752","article-title":"Tooth wear: A systematic review of treatment options","volume":"112","author":"Muts\n              EJ","year":"2014","unstructured":"Muts\n              EJ\n            , Van PeltH, EdelhoffD, KrejciI, & CuneM (2014) Tooth wear: A systematic review of treatment optionsJournal of Prosthetic Dentistry112(4) 752-759. doi:10.1016\/j.prosdent.2014.01.018"},{"key":"b8","series-title":"Open Dental Journal","first-page":"28","article-title":"The use of the digital smile design concept as an auxiliary tool in aesthetic rehabilitation: A case report","volume":"10","author":"Zanardi\n              PR","year":"2016","unstructured":"Zanardi\n              PR\n            , ZanardiRLR, ChaibRC, SesmaN, CostaB-N, Lagan\u00e1DC (2016) The use of the digital smile design concept as an auxiliary tool in aesthetic rehabilitation: A case reportOpen Dental Journal1028-34. doi:10.2174\/1874210601610010028"},{"issue":"2","key":"b9","series-title":"International Journal of Esthetic Dentistry","first-page":"146","article-title":"Wax-up and mock-up. A guide for anterior periodontal and restorative treatments","volume":"9","author":"Gurrea\n              J","year":"2014","unstructured":"Gurrea\n              J\n             & BrugueraA (2014) Wax-up and mock-up. A guide for anterior periodontal and restorative treatmentsInternational Journal of Esthetic Dentistry9(2) 146-162."},{"key":"b10","series-title":"Cosmetic and Investigational Dentistry","first-page":"45","article-title":"Conventional and digital workflow planning for maxillary teeth restoration with porcelain laminate veneers: A clinical report","volume":"14","author":"Alshali\n              S","year":"2022","unstructured":"Alshali\n              S\n             & AsaliR (2022) Conventional and digital workflow planning for maxillary teeth restoration with porcelain laminate veneers: A clinical reportCosmetic and Investigational Dentistry1445-53. doi:10.2147\/CCIDE.S346743"},{"issue":"4","key":"b11","series-title":"Clinical Oral Investigations","first-page":"1589","article-title":"Digital planning and guided dual technique in esthetic crown lengthening: A randomized controlled clinical trial","volume":"27","author":"Carrera\n              TMI","year":"2023","unstructured":"Carrera\n              TMI\n            , FreireAEN, de OliveiraGJPL, Dos Reis NicolauS, PichotanoEC, JuniorNVR, PiresLC, & PigossiSC (2023) Digital planning and guided dual technique in esthetic crown lengthening: A randomized controlled clinical trialClinical Oral Investigations27(4) 1589-1603. doi:10.1007\/s00784-022-04780-8"},{"issue":"1","key":"b12","series-title":"Journal of Esthetic and Restorative Dentistry","first-page":"5","article-title":"Digital workflow in full-arch implant rehabilitation with segmented minimally veneered monolithic zirconia fixed dental prostheses: 2-year clinical follow-up","volume":"30","author":"Papaspyridakos\n              P","year":"2018","unstructured":"Papaspyridakos\n              P\n            , KangK, DeFuriaC, AminS, KudaraY & WeberH-P (2018) Digital workflow in full-arch implant rehabilitation with segmented minimally veneered monolithic zirconia fixed dental prostheses: 2-year clinical follow-upJournal of Esthetic and Restorative Dentistry30(1) 5-13. doi:10.1111\/jerd.12323"},{"issue":"5","key":"b13","series-title":"Healthcare (Basel)","first-page":"679","article-title":"The complete digital workflow in fixed prosthodontics updated: A systematic review","volume":"11","author":"Bernauer\n              SA","year":"2023","unstructured":"Bernauer\n              SA\n            , ZitzmannNU, & JodaT (2023) The complete digital workflow in fixed prosthodontics updated: A systematic reviewHealthcare (Basel)11(5) 679. doi:10.3390\/healthcare11050679"},{"issue":"5","key":"b14","series-title":"American Journal of Orthodontics & Dentofacial Orthopedics","first-page":"470","article-title":"The \u201cWits\u201d appraisal of jaw disharmony","volume":"124","author":"Jacobson\n              A","year":"2003","unstructured":"Jacobson\n              A\n            \n           (2003) The \u201cWits\u201d appraisal of jaw disharmonyAmerican Journal of Orthodontics & Dentofacial Orthopedics124 (5) 470-479."},{"issue":"16","key":"b15","series-title":"Applied Sciences","first-page":"7249","article-title":"Occlusal splint therapy followed by orthodontic molar intrusion as an effective treatment method to treat patients with temporomandibular disorder: A retrospective study","volume":"11","author":"Nemes\n              B","year":"2021","unstructured":"Nemes\n              B\n            , FrankD, PuigdollersA, & Mart\u00ednD (2021) Occlusal splint therapy followed by orthodontic molar intrusion as an effective treatment method to treat patients with temporomandibular disorder: A retrospective studyApplied Sciences11(16) 7249. doi.org\/10.3390\/app11167249"},{"issue":"2","key":"b16","series-title":"Angle Orthodontist","first-page":"103","article-title":"Condylar axis position, as determined by the occlusion and measured by the CPI instrument, and signs and symptoms of temporomandibular dysfunction","volume":"69","author":"Crawford\n              SD","year":"1999","unstructured":"Crawford\n              SD\n            \n           (1999) Condylar axis position, as determined by the occlusion and measured by the CPI instrument, and signs and symptoms of temporomandibular dysfunctionAngle Orthodontist69(2) 103-115."},{"issue":"3","key":"b17","series-title":"Journal of Clinical Orthodontics","first-page":"182","article-title":"Functional occlusion for the orthodontist. Part III","volume":"15","author":"Roth\n              RH","year":"1981","unstructured":"Roth\n              RH\n            \n           (1981) Functional occlusion for the orthodontist. Part IIIJournal of Clinical Orthodontics15(3) 182-198."},{"key":"b18","series-title":"American Journal of Orthodontics and Dentofacial Orthopedics","first-page":"S216","article-title":"Evolution of occlusion and temporomandibular disorder in orthodontics: Past, present, and future","volume":"147","author":"Okeson\n              JP","year":"2015","unstructured":"Okeson\n              JP\n            \n           (2015) Evolution of occlusion and temporomandibular disorder in orthodontics: Past, present, and futureAmerican Journal of Orthodontics and Dentofacial Orthopedics147(5 Suppl) S216-S223."},{"issue":"27","key":"b19","series-title":"Frontiers of Oral and Maxillofacial Medicine","article-title":"Considerations for virtual surgical planning and simulation in orthognathic surgery-a narrative review","volume":"2","author":"Kwon\n              TG","year":"2020","unstructured":"Kwon\n              TG\n            , LeeST, ChoiSY, & KimJW (2020) Considerations for virtual surgical planning and simulation in orthognathic surgery-a narrative reviewFrontiers of Oral and Maxillofacial Medicine2(27) doi:10.21037\/fomm-20-54"},{"issue":"1","key":"b20","series-title":"Scientific Reports","first-page":"13317","article-title":"Validation of a patient-specific system for mandible-first bimaxillary surgery: ramus and implant positioning precision assessment and guide design comparison","volume":"10","author":"Badiali\n              G","year":"2020","unstructured":"Badiali\n              G\n            , BeviniM, RuggieroF, CercenelliL, LoveroE, de SimoneE, RucciP, BianchiA, & MarchettiC (2020) Validation of a patient-specific system for mandible-first bimaxillary surgery: ramus and implant positioning precision assessment and guide design comparisonScientific Reports10(1) 13317. doi:10.1038\/s41598-020-70107-w."},{"issue":"1","key":"b21","series-title":"Dental Press Journal of Orthodontics","first-page":"89","article-title":"3D virtual planning in orthognathic surgery and CAD\/CAM surgical splints generation in one patient with craniofacial microsomia: a case report","volume":"21","author":"Vale\n              F","year":"2016","unstructured":"Vale\n              F\n            , ScherzbergJ, CavaleiroJ, SanzD, CarameloF, Mal\u00f3L,& MarcelinoJP (2016) 3D virtual planning in orthognathic surgery and CAD\/CAM surgical splints generation in one patient with craniofacial microsomia: a case reportDental Press Journal of Orthodontics21(1) 89-100. doi:10.1590\/2177-6709.21.1.089-100.oar"},{"key":"b22","series-title":"Journal of Dentistry","first-page":"105014","article-title":"Evaluating the influence of palate scanning on the accuracy of complete-arch digital impressions\u2013An in vitro study","volume":"145","author":"Schmalzl\n              J","year":"2024","unstructured":"Schmalzl\n              J\n            , KeskenyG\u00c1, HermannP, P\u00e1lA, G\u00e9cziZ, Borb\u00e9lyJ, & R\u00f3thI (2024) Evaluating the influence of palate scanning on the accuracy of complete-arch digital impressions\u2013An in vitro studyJournal of Dentistry145105014. doi:10.1016\/j.jdent.2024.105014"},{"issue":"2","key":"b23","series-title":"Orthodontics & Craniofacial Research","first-page":"229","article-title":"Accuracy of 3D virtual surgical planning for maxillary positioning and orientation in orthognathic surgery","volume":"23","author":"Tonin\n              RH","year":"2020","unstructured":"Tonin\n              RH\n            , FilhoLI, YamashitaAL, FerrazFWdS, TolentinoEdS, PrevidelliITdS, BrumB, IwakiLCV (2020) Accuracy of 3D virtual surgical planning for maxillary positioning and orientation in orthognathic surgeryOrthodontics & Craniofacial Research23(2) 229-236. doi:10.1111\/ocr.12363"},{"issue":"9","key":"b24","series-title":"Journal of Clinical Medicine","first-page":"2385","article-title":"3D printing and virtual surgical planning in oral and maxillofacial surgery","volume":"11","author":"Zoabi\n              A","year":"2022","unstructured":"Zoabi\n              A\n            , RedenskiI, OrenD, KasemA, ZigronA, DaoudS, MoskovichL, KablanF, & SroujiS (2022) 3D printing and virtual surgical planning in oral and maxillofacial surgeryJournal of Clinical Medicine11(9) 2385. doi:10.3390\/jcm11092385"}],"container-title":["Operative 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