{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:33:10Z","timestamp":1782603190727,"version":"3.54.5"},"reference-count":15,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Charcot-Marie-Tooth disease (CMTD) is a hereditary peripheral neuropathy and is characterized by progressive muscle atrophy and motor-sensory disorders in all 4 limbs. Most reports have indicated that major challenges with general anesthetic administration in CMTD patients are the appropriate use of nondepolarizing muscle relaxants and preparation for malignant hyperthermia in neuromuscular disease. Moderate sedation may be associated with the same complications as those of general anesthesia, as well as dysfunction of the autonomic nervous system, reduced perioperative respiratory function, difficulty in positioning, and sensitivity to intravenous anesthetic agents. We decided to use intravenous sedation in a CMTD patient and administered midazolam initially and propofol continuously, with total doses of 1.5 mg and 300 mg, respectively. Anesthesia was completed in 3 hours and 30 minutes without adverse events. We suggest that dental anesthetic treatment with propofol and midazolam may be effective for patients with CMTD.<\/jats:p>","DOI":"10.2344\/15-00010r1.1","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T22:05:52Z","timestamp":1465250752000},"page":"80-83","source":"Crossref","is-referenced-by-count":11,"title":["Anesthetic Management of a Patient With Charcot-Marie-Tooth Disease"],"prefix":"10.2344","volume":"63","author":[{"given":"Naohiro","family":"Ohshita","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeko","family":"Oka","sequence":"additional","affiliation":[{"name":"Marunouchi Dental Clinic, Kagawa, Japan, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaname","family":"Tsuji","sequence":"additional","affiliation":[{"name":"First Department of Oral and Maxillofacial Surgery, Osaka Dental University, Osaka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Yoshida","sequence":"additional","affiliation":[{"name":"First Department of Oral and Maxillofacial Surgery, Osaka Dental University, Osaka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shosuke","family":"Morita","sequence":"additional","affiliation":[{"name":"First Department of Oral and Maxillofacial Surgery, Osaka Dental University, Osaka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Momota","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo M.","family":"Tsutsumi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Tokushima University, Tokushima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1191","reference":[{"key":"i0003-3006-63-2-80-b01","series-title":"Genes","first-page":"13","article-title":"Genetics of Charcot-Marie-Tooth (CMT) disease within the frame of the Human Genome Project success","volume":"22","author":"Timmerman \n              V,","year":"2014","unstructured":"Timmerman \n              V, \n            \n            \n              Strickland \n              AV, \n            \n            \n              Z\u00fcchner \n              S. \n            \n          \n          Genetics of Charcot-Marie-Tooth (CMT) disease within the frame of the Human Genome Project success. Genes. 2014;22:13\u201332."},{"key":"i0003-3006-63-2-80-b02","series-title":"Brain","first-page":"259","article-title":"The clinical features of hereditary motor and sensory neuropathy types I and II","volume":"103","author":"Harding \n              AE,","year":"1980","unstructured":"Harding \n              AE, \n            \n            \n              Thomas \n              PK. \n            \n          \n          The clinical features of hereditary motor and sensory neuropathy types I and II. Brain. 1980;103:259\u2013280."},{"key":"i0003-3006-63-2-80-b03","series-title":"S Afr Med J","first-page":"605","article-title":"Anaesthesia for abdominal hysterectomy in Charcot-Marie-Tooth disease. A case report","volume":"67","author":"Roelofse \n              JA,","year":"1985","unstructured":"Roelofse \n              JA, \n            \n            \n              Shipton \n              EA. \n            \n          \n          Anaesthesia for abdominal hysterectomy in Charcot-Marie-Tooth disease. A case report. S Afr Med J. 1985;67:605\u2013606."},{"key":"i0003-3006-63-2-80-b04","series-title":"ASN Neuro","first-page":"185","article-title":"Charcot-Marie-Tooth disease, psychiatric indicators and quality of life: a systematic review","volume":"27","author":"Cordeiro \n              JL,","year":"2014","unstructured":"Cordeiro \n              JL, \n            \n            \n              Marques \n              W, \n            \n            \n              Hallak \n              JE, \n            \n            \n              Os\u00f3rio \n              FL. \n            \n          \n          Charcot-Marie-Tooth disease, psychiatric indicators and quality of life: a systematic review. ASN Neuro. 2014;27:185\u2013192."},{"key":"i0003-3006-63-2-80-b05","series-title":"Can J Anaesth","first-page":"984","article-title":"Mivacurium-induced neuromuscular block in adult patients suffering from Charcot-Marie-Tooth disease","volume":"53","author":"Schmitt \n              HJ,","year":"2006","unstructured":"Schmitt \n              HJ, \n            \n            \n              M\u00fcnster \n              T. \n            \n          \n          Mivacurium-induced neuromuscular block in adult patients suffering from Charcot-Marie-Tooth disease. Can J Anaesth. 2006;53:984\u2013988."},{"key":"i0003-3006-63-2-80-b06","series-title":"Lung","first-page":"1","article-title":"Disorders of pulmonary function, sleep, and the upper airway in Charcot-Marie-Tooth disease","volume":"185","author":"Aboussouan \n              LS,","year":"2007","unstructured":"Aboussouan \n              LS, \n            \n            \n              Lewis \n              RA, \n            \n            \n              Shy \n              ME. \n            \n          \n          Disorders of pulmonary function, sleep, and the upper airway in Charcot-Marie-Tooth disease. Lung. 2007;185:1\u20137."},{"key":"i0003-3006-63-2-80-b07","series-title":"Can J Anaesth","first-page":"398","article-title":"Anaesthesia for Charcot-Marie-Tooth disease: a review of 86 cases","volume":"39","author":"Antognini \n              JF.","year":"1992","unstructured":"Antognini \n              JF. \n            \n          \n          Anaesthesia for Charcot-Marie-Tooth disease: a review of 86 cases. Can J Anaesth. 1992;39:398\u2013400."},{"key":"i0003-3006-63-2-80-b08","series-title":"Br J Anaesth","first-page":"1061","article-title":"Anaesthetic management of a patient with Charcot-Marie-Tooth disease for staged diaphragmatic plication","volume":"110","author":"Pasha \n              TM,","year":"2013","unstructured":"Pasha \n              TM, \n            \n            \n              Knowles \n              A. \n            \n          \n          Anaesthetic management of a patient with Charcot-Marie-Tooth disease for staged diaphragmatic plication. Br J Anaesth. 2013;110:1061\u20131063."},{"key":"i0003-3006-63-2-80-b09","series-title":"Arch Intern Med","first-page":"1389","article-title":"Respiratory muscle weakness in Charcot-Marie-Tooth disease","volume":"149","author":"Nathanson \n              BN,","year":"1989","unstructured":"Nathanson \n              BN, \n            \n            \n              Yu \n              DG, \n            \n            \n              Chan \n              CK. \n            \n          \n          Respiratory muscle weakness in Charcot-Marie-Tooth disease. Arch Intern Med. 1989;149:1389\u20131391."},{"key":"i0003-3006-63-2-80-b10","series-title":"Anesth Analg","first-page":"305","article-title":"Anesthetic management for the child with Charcot-Marie-Tooth disease","volume":"74","author":"Greenberg \n              RS,","year":"1992","unstructured":"Greenberg \n              RS, \n            \n            \n              Parker \n              SD. \n            \n          \n          Anesthetic management for the child with Charcot-Marie-Tooth disease. Anesth Analg. 1992;74:305\u2013307."},{"key":"i0003-3006-63-2-80-b11","series-title":"Can J Anaesth","first-page":"56","article-title":"Response to atracurium and mivacurium in a patient with Charcot-Marie-Tooth disease","volume":"45","author":"Naguib \n              M,","year":"1998","unstructured":"Naguib \n              M, \n            \n            \n              Samarkandi \n              AH. \n            \n          \n          Response to atracurium and mivacurium in a patient with Charcot-Marie-Tooth disease. Can J Anaesth. 1998;45:56\u201359."},{"key":"i0003-3006-63-2-80-b12","series-title":"BMC Anesth","first-page":"8","article-title":"Catherter-based distal sciatic nerve block in patients with Charcot-Marie-Tooth disease","volume":"14","author":"Schmitt \n              HJ,","year":"2014","unstructured":"Schmitt \n              HJ, \n            \n            \n              Huberth \n              S, \n            \n            \n              Huber \n              H, \n            \n            \n              Munster \n              T. \n            \n          \n          Catherter-based distal sciatic nerve block in patients with Charcot-Marie-Tooth disease. BMC Anesth. 2014;14:8."},{"key":"i0003-3006-63-2-80-b13","series-title":"Anesth Analg","first-page":"1138","article-title":"Anesthetic management of patients undergoing deep brain stimulator insertion","volume":"110","author":"Venkatraghavan \n              L,","year":"2010","unstructured":"Venkatraghavan \n              L, \n            \n            \n              Luciano \n              M, \n            \n            \n              Manninen \n              P. \n            \n          \n          Anesthetic management of patients undergoing deep brain stimulator insertion. Anesth Analg. 2010;110:1138\u20131145."},{"key":"i0003-3006-63-2-80-b14","series-title":"Pharmacotherapy","first-page":"19S","article-title":"Bispectral index monitoring in the intensive care unit provides more signal than noise","volume":"25","author":"Fraser \n              GL,","year":"2005","unstructured":"Fraser \n              GL, \n            \n            \n              Riker \n              RR. \n            \n          \n          Bispectral index monitoring in the intensive care unit provides more signal than noise. Pharmacotherapy. 2005;25:19S\u201327S."},{"key":"i0003-3006-63-2-80-b15","series-title":"Can J Anaesth","first-page":"829","article-title":"Arrhythmia and Charcot-Marie-Tooth disease during anesthesia","volume":"47","author":"Tetzlaff \n              JE,","year":"2000","unstructured":"Tetzlaff \n              JE, \n            \n            \n              Schwendt \n              I. \n            \n          \n          Arrhythmia and Charcot-Marie-Tooth disease during anesthesia. Can J Anaesth. 2000;47:829."}],"container-title":["Anesthesia Progress"],"original-title":[],"link":[{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/63\/2\/article-p80.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/anesthesia-progress\/article-pdf\/63\/2\/80\/2100869\/15-00010r1_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/downloadpdf\/journals\/anpr\/63\/2\/article-p80.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/downloadpdf\/journals\/anpr\/63\/2\/article-p80.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T12:34:47Z","timestamp":1728304487000},"score":1,"resource":{"primary":{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/63\/2\/article-p80.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":15,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.2344\/15-00010r1.1","relation":{},"ISSN":["0003-3006","1878-7177"],"issn-type":[{"value":"0003-3006","type":"print"},{"value":"1878-7177","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}