{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T17:37:37Z","timestamp":1789925857429,"version":"4.0.1"},"reference-count":17,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016]]},"abstract":"We describe the case of a 37-year-old woman who had been diagnosed with Ehlers-Danlos syndrome (EDS) 4 years earlier and was scheduled to undergo removal of synovial chondromatosis in the temporomandibular joint. EDS is a heritable connective tissue disorder and has 6 types. In this case, the patient was classified into EDS hypermobility type. The major clinical feature of this type is joint hypermobility. The patient had sprain or subluxation of the elbows and ankles and dislocation of the knees. Anticipated problems during general anesthesia would be affected by the disease type. For this patient, extra attention was directed to positional injury\u2013induced neuropathy and articular luxation, cutaneous injuries, injuries related to intubation and ventilation, and postoperative pain. Anesthesia was induced with propofol, remifentanil, and rocuronium and maintained with oxygen-air-desflurane, propofol, remifentanil, fentanyl, and rocuronium. In this case, the patient was safely managed without adverse events.<\/jats:p>","DOI":"10.2344\/16-00003.1","type":"journal-article","created":{"date-parts":[[2016,12,14]],"date-time":"2016-12-14T21:58:50Z","timestamp":1481752730000},"page":"204-207","source":"Crossref","is-referenced-by-count":9,"title":["Anesthetic Management of a Patient With Ehlers-Danlos Syndrome"],"prefix":"10.2344","volume":"63","author":[{"given":"Naohiro","family":"Ohshita","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Osaka Dental University, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Kanazumi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Osaka Dental University, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaname","family":"Tsuji","sequence":"additional","affiliation":[{"name":"First Department of Oral and Maxillofacial Surgery, Osaka Dental University, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Yoshida","sequence":"additional","affiliation":[{"name":"First Department of Oral and Maxillofacial Surgery, Osaka Dental University, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shosuke","family":"Morita","sequence":"additional","affiliation":[{"name":"First Department of Oral and Maxillofacial Surgery, Osaka Dental University, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Momota","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Osaka Dental University, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo M.","family":"Tsutsumi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Tokushima University, Tokushima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1191","reference":[{"key":"i0003-3006-63-4-204-b01","series-title":"Am J Med Genet","first-page":"31","article-title":"Ehlers-Danlos syndromes: revised nosology, Villefranche, 1997. 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Iran J Neurol. 2014;13:190\u2013208."},{"key":"i0003-3006-63-4-204-b03","series-title":"Am J Med Genet C Semin Med Genet","first-page":"17","article-title":"Molecular genetics in classic Ehlers-Danlos syndrome","volume":"139C","author":"Malfait \n F,","year":"2005","unstructured":"Malfait \n F, \n \n \n De Paepe \n A. \n \n \n Molecular genetics in classic Ehlers-Danlos syndrome. Am J Med Genet C Semin Med Genet. 2005;139C:17\u201323."},{"key":"i0003-3006-63-4-204-b04","series-title":"Am J Med Genet A","first-page":"3010","article-title":"Nosology and inheritance pattern(s) of joint hypermobility syndrome and Ehlers-Danlos syndrome, hypermobility type: a study of intrafamilial and interfamilial variability in 23 Italian pedigrees","volume":"164A","author":"Castori \n M,","year":"2014","unstructured":"Castori \n M, \n \n \n Dordoni \n C, \n \n \n Valiante \n M, \n \n et al. \n Nosology and inheritance pattern(s) of joint hypermobility syndrome and Ehlers-Danlos syndrome, hypermobility type: a study of intrafamilial and interfamilial variability in 23 Italian pedigrees. Am J Med Genet A. 2014;164A:3010\u20133020."},{"key":"i0003-3006-63-4-204-b05","series-title":"Genet Med","first-page":"597","article-title":"Clinical and genetic aspects of Ehlers-Danlos syndrome, classic type","volume":"12","author":"Malfait \n F,","year":"2010","unstructured":"Malfait \n F, \n \n \n Wenstrup \n RJ, \n \n \n De Paepe \n A. \n \n \n Clinical and genetic aspects of Ehlers-Danlos syndrome, classic type. Genet Med. 2010;12:597\u2013605."},{"key":"i0003-3006-63-4-204-b06","series-title":"Am J Med Genet C Semin Med Genet","first-page":"107","article-title":"Neurodevelopmental attributes of joint hypermobility syndrome\/Ehlers-Danlos syndrome, hypermobility type: update and perspectives","volume":"169","author":"Ghibellini \n G,","year":"2015","unstructured":"Ghibellini \n G, \n \n \n Brancati \n F, \n \n \n Castori \n M. \n \n \n Neurodevelopmental attributes of joint hypermobility syndrome\/Ehlers-Danlos syndrome, hypermobility type: update and perspectives. Am J Med Genet C Semin Med Genet. 2015;169:107\u2013116."},{"key":"i0003-3006-63-4-204-b07","series-title":"BMC Musculoskelet Disord","first-page":"361","article-title":"Psychometric evaluation of the Disabilities of the Arm, Shoulder and Hand (DASH) with Dupuytren's contracture: validity evidence using Rasch modeling","volume":"15","author":"Forget \n NJ,","year":"2014","unstructured":"Forget \n NJ, \n \n \n Jerosch-Herold \n C, \n \n \n Shepstone \n L, \n \n \n Higgins \n J. \n \n \n Psychometric evaluation of the Disabilities of the Arm, Shoulder and Hand (DASH) with Dupuytren's contracture: validity evidence using Rasch modeling. BMC Musculoskelet Disord. 2014;15:361."},{"key":"i0003-3006-63-4-204-b08","series-title":"J Pain Symptom Manage","first-page":"370","article-title":"Pain in Ehlers-Danlos syndrome is common, severe, and associated with functional impairment","volume":"40","author":"Voermans \n NC,","year":"2010","unstructured":"Voermans \n NC, \n \n \n Knoop \n H, \n \n \n Bleijenberg \n G, \n \n \n van Engelen \n BG. \n \n \n Pain in Ehlers-Danlos syndrome is common, severe, and associated with functional impairment. J Pain Symptom Manage. 2010;40:370\u2013378."},{"key":"i0003-3006-63-4-204-b09","series-title":"J Craniomaxillofac Surg","first-page":"473","article-title":"Preliminary report of Ki-67 reactivity in synovial chondromatosis of the temporomandibular joint: an immunohistochemical study","volume":"41","author":"Yoshida \n H,","year":"2013","unstructured":"Yoshida \n H, \n \n \n Tsuji \n K, \n \n \n Oshiro \n N, \n \n \n Wato \n M, \n \n \n Morita \n S. \n \n \n Preliminary report of Ki-67 reactivity in synovial chondromatosis of the temporomandibular joint: an immunohistochemical study. J Craniomaxillofac Surg. 2013;41:473\u2013475."},{"key":"i0003-3006-63-4-204-b10","series-title":"J Radiol Case Rep","first-page":"63","article-title":"Vascular type Ehlers-Danlos syndrome with fatal spontaneous rupture of a right common iliac artery dissection: case report and review of literature","volume":"8","author":"Abayazeed \n A,","year":"2014","unstructured":"Abayazeed \n A, \n \n \n Hayman \n E, \n \n \n Moghadamfalahi \n M, \n \n \n Cain \n D. \n \n \n Vascular type Ehlers-Danlos syndrome with fatal spontaneous rupture of a right common iliac artery dissection: case report and review of literature. J Radiol Case Rep. 2014;8:63\u201369."},{"key":"i0003-3006-63-4-204-b11","series-title":"Best Pract Res Clin Rheumatol","first-page":"165","article-title":"Ehlers-Danlos syndromes and Marfan syndrome","volume":"22","author":"Callewaert \n B,","year":"2008","unstructured":"Callewaert \n B, \n \n \n Malfait \n F, \n \n \n Loeys \n B, \n \n \n De Paepe \n A. \n \n \n Ehlers-Danlos syndromes and Marfan syndrome. Best Pract Res Clin Rheumatol. 2008;22:165\u2013189."},{"key":"i0003-3006-63-4-204-b12","series-title":"Anesthesiology","first-page":"266","article-title":"Anesthetic considerations for Ehlers-Danlos syndrome","volume":"52","author":"Dolan \n P,","year":"1980","unstructured":"Dolan \n P, \n \n \n Sisko \n F, \n \n \n Riley \n E. \n \n \n Anesthetic considerations for Ehlers-Danlos syndrome. Anesthesiology. 1980;52:266\u2013269."},{"key":"i0003-3006-63-4-204-b13","series-title":"Orphanet J Rare Dis","first-page":"109","article-title":"Recommendations for anesthesia and perioperative management in patients with Ehlers-Danlos syndrome(s)","volume":"9","author":"Wiesmann \n T,","year":"2014","unstructured":"Wiesmann \n T, \n \n \n Castori \n M, \n \n \n Malfait \n F, \n \n \n Wulf \n H. \n \n \n Recommendations for anesthesia and perioperative management in patients with Ehlers-Danlos syndrome(s). Orphanet J Rare Dis. 2014;9:109."},{"key":"i0003-3006-63-4-204-b14","series-title":"Can J Anaesth","first-page":"1308","article-title":"Anesthetic management of a parturient with hypermobility phenotype but possible vascular genotype Ehlers-Danlos syndrome","volume":"62","author":"Fedoruk \n K,","year":"2015","unstructured":"Fedoruk \n K, \n \n \n Chong \n K, \n \n \n Sermer \n M, \n \n \n Carvalho \n JC. \n \n \n Anesthetic management of a parturient with hypermobility phenotype but possible vascular genotype Ehlers-Danlos syndrome. Can J Anaesth. 2015;62:1308\u20131312."},{"key":"i0003-3006-63-4-204-b15","series-title":"Anesth Analg","first-page":"63","article-title":"A comparison of desflurane versus propofol: the effects on early postoperative lung function in overweight patients","volume":"113","author":"Zoremba \n M,","year":"2011","unstructured":"Zoremba \n M, \n \n \n Dette \n F, \n \n \n Hunecke \n T, \n \n \n Eberhart \n L, \n \n \n Braunecker \n S, \n \n \n Wulf \n H. \n \n \n A comparison of desflurane versus propofol: the effects on early postoperative lung function in overweight patients. Anesth Analg. 2011;113:63\u201369."},{"key":"i0003-3006-63-4-204-b16","series-title":"Braz J Anesthesiol","first-page":"12","article-title":"Effects of a novel method of anesthesia combining propofol and volatile anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery","volume":"66","author":"Kawano \n H,","year":"2016","unstructured":"Kawano \n H, \n \n \n Ohshita \n N, \n \n \n Katome \n K, \n \n et al. \n Effects of a novel method of anesthesia combining propofol and volatile anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery. Braz J Anesthesiol. 2016;66:12\u201318."},{"key":"i0003-3006-63-4-204-b17","series-title":"J Neurol","first-page":"13","article-title":"Joint hypermobility as a distinctive feature in the differential diagnosis of myopathies","volume":"256","author":"Voermans \n NC,","year":"2009","unstructured":"Voermans \n NC, \n \n \n Bonnemann \n CG, \n \n \n Hamel \n BC, \n \n \n Jungbluth \n H, \n \n \n van Engelen \n BG. \n \n \n Joint hypermobility as a distinctive feature in the differential diagnosis of myopathies. J Neurol. 2009;256:13\u201327."}],"container-title":["Anesthesia Progress"],"original-title":[],"link":[{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/63\/4\/article-p204.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/anesthesia-progress\/article-pdf\/63\/4\/204\/2101589\/16-00003_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/downloadpdf\/journals\/anpr\/63\/4\/article-p204.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/downloadpdf\/journals\/anpr\/63\/4\/article-p204.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T12:37:16Z","timestamp":1728304636000},"score":1,"resource":{"primary":{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/63\/4\/article-p204.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":17,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.2344\/16-00003.1","relation":{},"ISSN":["0003-3006","1878-7177"],"issn-type":[{"value":"0003-3006","type":"print"},{"value":"1878-7177","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}