{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:11:46Z","timestamp":1790248306201,"version":"4.1.0"},"reference-count":18,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:p>Few reports exist in dentistry about the use of general anesthesia in children after liver transplant. In this paper, we report our experience utilizing general anesthesia for oral surgery in a 9-year-old girl who had undergone living donor liver transplantation. She was diagnosed with hepatoblastoma at 4 months of age and underwent a living donor liver transplant at 7 months of age. Due to a maxillary odontoma, impacted maxillary supernumerary teeth, and retained maxillary primary teeth, the patient was scheduled for general anesthesia. Preoperative blood tests revealed mild liver dysfunction, but no other abnormalities were noted. General anesthesia was administered with sevoflurane, rocuronium, fentanyl, and remifentanil, and no complications arose during the perioperative period. The patient was discharged without any significant issues the day after surgery. Precautions for the anesthetic management of children who have undergone living donor liver transplantation include assessing the patient for preoperative liver dysfunction and avoiding liver dysfunction caused by drugs used in conjunction with general anesthesia. Anesthetic agents and adjunctive medications should be carefully considered for use in patients with liver disease.<\/jats:p>","DOI":"10.2344\/24-0015","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:45:29Z","timestamp":1757378729000},"page":"172-176","source":"Crossref","is-referenced-by-count":0,"title":["General Anesthesia for a Child With a Living Donor Liver Transplant After Hepatoblastoma and Metastatic Lung Tumor Resection"],"prefix":"10.2344","volume":"72","author":[{"given":"Keiko","family":"Fujii-Abe","sequence":"first","affiliation":[{"name":"Department of Dental Anesthesiology, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Yaguchi","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Harigaya","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshio","family":"Hayakawa","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takumi","family":"Nagumo","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumi","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kawahara","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, School of Dental Medicine, Tsurumi University, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1191","reference":[{"issue":"1","key":"i1878-7177-72-3-172-b01","series-title":"Arch Stem Cell Ther","first-page":"1","article-title":"Molecular signatures of aggressive pediatric liver cancer","volume":"2","author":"Johnston ME","year":"2021","unstructured":"Johnston ME,\nTimchenko N. Molecular signatures of aggressive pediatric liver cancer. Arch Stem Cell Ther. 2021;2(1):1\u20134."},{"issue":"6","key":"i1878-7177-72-3-172-b02","series-title":"Hum Pathol","first-page":"512","article-title":"Primary hepatic tumors of childhood","volume":"14","author":"Weinberg AG","year":"1983","unstructured":"Weinberg AG,\nFinegold MJ. Primary hepatic tumors of childhood. Hum Pathol. 1983;14(6):512\u2013537."},{"key":"i1878-7177-72-3-172-b03","series-title":"Cancer","first-page":"1926","article-title":"Adriamycin and cisplatin for hepatoblastoma","volume":"56","author":"Quinn JJ","year":"1985","unstructured":"Quinn JJ,\nAltman AJ,\nRobinson HT,\nCooke RW,\nHight DW,\nFoster JH. Adriamycin and cisplatin for hepatoblastoma. Cancer. 1985;56:1926\u20131929."},{"key":"i1878-7177-72-3-172-b04","series-title":"Cancers","first-page":"720","article-title":"Liver transplantation for pediatric liver cancer","volume":"12","author":"Sindhi R","year":"2020","unstructured":"Sindhi R,\nRohan V,\nBukowinski A, et al. Liver transplantation for pediatric liver cancer. Cancers. 2020;12:720."},{"key":"i1878-7177-72-3-172-b05","series-title":"Can J Physiol Pharmacol","first-page":"1762","article-title":"General anesthesia and hepatic circulation","volume":"65","author":"Gelman S.","year":"1987","unstructured":"Gelman S. General anesthesia and hepatic circulation. Can J Physiol Pharmacol. 1987;65:1762\u20131779."},{"key":"i1878-7177-72-3-172-b06","series-title":"Anesth Med Dis","first-page":"340","article-title":"Anesthetic considerations for the patient with liver disease","volume":"25","author":"Hoetzel A","year":"2012","unstructured":"Hoetzel A,\nRyan H,\nSchmidt R. Anesthetic considerations for the patient with liver disease. Anesth Med Dis. 2012;25:340\u2013347."},{"issue":"3","key":"i1878-7177-72-3-172-b07","series-title":"J Clin Exp Hepatol","first-page":"238","article-title":"Surgery in a patient with liver disease","volume":"2","author":"Rai R","year":"2012","unstructured":"Rai R,\nNagral S,\nNagral A. Surgery in a patient with liver disease. J Clin Exp Hepatol. 2012;2(3):238\u2013246."},{"key":"i1878-7177-72-3-172-b08","series-title":"Int Anesthesiol Clin","first-page":"107","article-title":"Anesthesia for pediatric patients who have had a transplant","volume":"33","author":"Black AE.","year":"1995","unstructured":"Black AE. Anesthesia for pediatric patients who have had a transplant. Int Anesthesiol Clin. 1995;33:107\u2013123."},{"key":"i1878-7177-72-3-172-b09","series-title":"Anesthesiol Res Pract","first-page":"1","article-title":"the Influence of pharmacological with sevoflurane on incidence of early allograft dysfunction in liver transplant recipients","volume":"2012","author":"Minou AF.","year":"2012","unstructured":"Minou AF.,\nDzyadzko AM,\nShcherba AE,\nRummo OO. the Influence of pharmacological with sevoflurane on incidence of early allograft dysfunction in liver transplant recipients. Anesthesiol Res Pract. 2012;2012:1\u20135."},{"issue":"8","key":"i1878-7177-72-3-172-b10","series-title":"Can J Anaesth","first-page":"753","article-title":"Liver function after sevoflurane or isoflurane aneaesthesia in neurosurgical patients","volume":"45","author":"Nishiyama T","year":"1998","unstructured":"Nishiyama T,\nYokoyama T,\nHanaoka K, Liver function after sevoflurane or isoflurane aneaesthesia in neurosurgical patients. Can J Anaesth. 1998;45(8):753\u2013756."},{"key":"i1878-7177-72-3-172-b11","series-title":"Liver Transpl","first-page":"1150","article-title":"The effects of desflurane and propofol-remifentanil on postoperative hepatic and renal functions after right hepatectomy in liver donors","volume":"14","author":"Ko JS","year":"2008","unstructured":"Ko JS,\nGwas MS,\nChoi SJ, et al. The effects of desflurane and propofol-remifentanil on postoperative hepatic and renal functions after right hepatectomy in liver donors. Liver Transpl. 2008;14:1150\u20131158."},{"key":"i1878-7177-72-3-172-b12","series-title":"Br J Clin Pharmacol","first-page":"139","article-title":"The pharmacokinetics and pharmacodynamics of rocuronium in patients with hepatic cirrhosis","volume":"44","author":"van Miert MH","year":"1997","unstructured":"van Miert MH,\nEsatwood NB,\nBoyd AH,\nParker CJR,\nHunter JM. The pharmacokinetics and pharmacodynamics of rocuronium in patients with hepatic cirrhosis. Br J Clin Pharmacol. 1997;44:139\u2013144."},{"key":"i1878-7177-72-3-172-b13","series-title":"Br J Anaesth","first-page":"624","article-title":"Pharmacokinetics and pharmacodynamics od cisatracurium in patients with end-stage liver disease undergoing liver transplantation","volume":"76","author":"De Wolf AM","year":"1996","unstructured":"De Wolf AM,\nFreeman JA,\nScott VL, et al. Pharmacokinetics and pharmacodynamics od cisatracurium in patients with end-stage liver disease undergoing liver transplantation. Br J Anaesth. 1996;76:624\u2013628."},{"key":"i1878-7177-72-3-172-b14","series-title":"Oral Surg","first-page":"153","article-title":"Gardner\u2019s syndrome (intestinal polyposis, osteomas, sebaceous cysts) and a new dental discovery","volume":"15","author":"Fader M","year":"1962","unstructured":"Fader M,\nKline SN,\nSpatz S,\nZubrow HJGardner\u2019s syndrome (intestinal polyposis, osteomas, sebaceous cysts) and a new dental discovery. Oral Surg. 1962;15:153\u2013172."},{"key":"i1878-7177-72-3-172-b15","series-title":"J Gastroenterol Hepatol","first-page":"527","article-title":"Oral manifestations in patients with familial adenomatous polyposis: a systematic review and meta-analysis","volume":"31","author":"Almeida FT","year":"2016","unstructured":"Almeida FT,\nPacheco-Pereira C,\nPorporatti AL, et al. Oral manifestations in patients with familial adenomatous polyposis: a systematic review and meta-analysis. J Gastroenterol Hepatol. 2016;31:527\u2013540."},{"key":"i1878-7177-72-3-172-b16","series-title":"Gut","first-page":"867","article-title":"Hepatoblastoma and APC gene mutation in familial adenomatous polyposis","volume":"39","author":"Giardiello FM","year":"1996","unstructured":"Giardiello FM,\nPetersen GM,\nBrensinger JD, et al. Hepatoblastoma and APC gene mutation in familial adenomatous polyposis. Gut. 1996;39:867\u2013869."},{"key":"i1878-7177-72-3-172-b17","series-title":"J Oral Biosci","first-page":"180","article-title":"Genetics of supernumerary tooth formation","volume":"55","author":"Nakamura T","year":"2013","unstructured":"Nakamura T,\nFukumoto S. Genetics of supernumerary tooth formation. J Oral Biosci. 2013;55:180\u2013183."},{"key":"i1878-7177-72-3-172-b18","series-title":"J Craniomaxillofac Surg","first-page":"350","article-title":"Widespread radiopacity of jaw bones in familial adenomatosis coli","volume":"17","author":"Kubo K","year":"1989","unstructured":"Kubo K,\nMiyatani H,\nTakenoshita Y, et al. Widespread radiopacity of jaw bones in familial adenomatosis coli. J Craniomaxillofac Surg. 1989;17:350\u2013353."}],"container-title":["Anesthesia Progress"],"original-title":[],"link":[{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/72\/3\/article-p172.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/downloadpdf\/journals\/anpr\/72\/3\/article-p172.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/downloadpdf\/journals\/anpr\/72\/3\/article-p172.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:44:37Z","timestamp":1790246677000},"score":1,"resource":{"primary":{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/72\/3\/article-p172.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":18,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.2344\/24-0015","relation":{},"ISSN":["1878-7177","0003-3006"],"issn-type":[{"value":"1878-7177","type":"electronic"},{"value":"0003-3006","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]}}}