{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:56:26Z","timestamp":1781744186699,"version":"3.54.5"},"reference-count":10,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:p>Mixed connective tissue disease (MCTD) is an autoimmune disorder characterized by overlapping features of multiple connective tissue diseases in addition to anti-U1-ribonucleoprotein (RNP) antibodies and Raynaud\u2019s phenomenon. A 53-year-old female patient with MCTD, interstitial pneumonia, and idiopathic thrombocytopenic purpura underwent partial tongue resection under general anesthesia. Perioperative management included steroid coverage and careful titration of the oxygen concentration. Although venous access was difficult, the anesthetic course was uneventful. MCTD can present perioperative challenges including pulmonary and cardiac complications, effects of long-term steroid use, and airway and cardiovascular disturbances. Safe anesthesia for patients with MCTD requires assessment of disease activity and severity across multiple conditions and individualized management accordingly.<\/jats:p>","DOI":"10.2344\/25-0023","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:30:49Z","timestamp":1781742649000},"page":"110-111","source":"Crossref","is-referenced-by-count":0,"title":["General Anesthesia for Partial Tongue Resection in a Patient With Mixed Connective Tissue Disease: A Case Report"],"prefix":"10.2344","volume":"73","author":[{"given":"Hitoshi","family":"Higuch","sequence":"first","affiliation":[{"name":"Department of Dental Anesthesiology, Okayama University Hospital, Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumika","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Dental Anesthesiology and Special Care Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kota","family":"Miyake","sequence":"additional","affiliation":[{"name":"Dental Anesthesiology and Special Care Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saki","family":"Miyake","sequence":"additional","affiliation":[{"name":"Dental Anesthesiology and Special Care Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiko","family":"Nishioka","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Okayama University Hospital, Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Miyawaki","sequence":"additional","affiliation":[{"name":"Dental Anesthesiology and Special Care Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1191","reference":[{"issue":"1","key":"i1878-7177-73-2-110-b01","series-title":"Mod Rheumatol","first-page":"29","article-title":"2019 Diagnostic criteria for mixed connective tissue disease (MCTD): From the Japan research committee of the ministry of health, labor, and welfare for systemic autoimmune diseases","volume":"31","author":"Tanaka","year":"2021","unstructured":"Tanaka Y,\nKuwana M,\nFujii T, et al. 2019 Diagnostic criteria for mixed connective tissue disease (MCTD): From the Japan research committee of the ministry of health, labor, and welfare for systemic autoimmune diseases. 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J Anaesth Clin Pharmacol. 2008;24(2):211\u2013224."},{"issue":"1","key":"i1878-7177-73-2-110-b04","series-title":"Obstet Gynecol Cases Rev","first-page":"259","article-title":"Anaesthetic management of a parturient with mixed connective tissue disorder","volume":"11","author":"Gunasekaran","year":"2024","unstructured":"Gunasekaran A,\nVijayan V,\nVijayakumar K,\nSakkanan NV: Anaesthetic management of a parturient with mixed connective tissue disorder. Obstet Gynecol Cases Rev. 2024;11(1):259."},{"issue":"Suppl 1","key":"i1878-7177-73-2-110-b05","series-title":"Thorax","first-page":"ii1","article-title":"BTS guideline for oxygen use in adults in healthcare and emergency settings","volume":"72","author":"O\u2019Driscoll","year":"2017","unstructured":"O\u2019Driscoll BR,\nHoward LS,\nEaris J, et al. BTS guideline for oxygen use in adults in healthcare and emergency settings. 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