{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T01:10:08Z","timestamp":1730941808916,"version":"3.28.0"},"reference-count":3,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:p>Recently, intranasal dexmedetomidine (DEX) has been reported to be effective as a preanesthetic medication, mostly in healthy pediatric patients. We attempted to administer intranasal DEX premedication in this case to an adult patient with intellectual disability who previously had difficulty tolerating premedication with oral midazolam. Using an intranasal atomization delivery device (MAD Nasal, Teleflex), we administered 1.5 \u00b5g\/kg of DEX intranasally and were able to achieve adequate sedation, which facilitated a smooth mask induction of general anesthesia with sevoflurane. Premedication with intranasal DEX may be a useful method for enabling induction of general anesthesia in adult patients with intellectual disabilities.<\/jats:p>","DOI":"10.2344\/anpr-23-0057","type":"journal-article","created":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T11:07:48Z","timestamp":1725880068000},"page":"147-148","source":"Crossref","is-referenced-by-count":0,"title":["Intranasal Premedication With Dexmedetomidine in an Adult Patient With Intellectual Disabilities: A Case Report"],"prefix":"10.2344","volume":"71","author":[{"given":"Jotaro","family":"Tanaka","sequence":"first","affiliation":[{"name":"Dental Anesthesiology and Special Care Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saki","family":"Miyake","sequence":"additional","affiliation":[{"name":"Dental Anesthesiology and Special Care Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maki","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Okayama University Hospital, Okayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukiko","family":"Nishioka","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Okayama University Hospital, Okayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Higuchi","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Okayama University Hospital, Okayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takuya","family":"Miyawaki","sequence":"additional","affiliation":[{"name":"Dental Anesthesiology and Special Care Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1191","reference":[{"key":"i1878-7177-71-3-147-b01","series-title":"Can J Anesth","first-page":"947","article-title":"The effects of intranasal dexmedetomidine premedication in children: a systematic review and meta-analysis","volume":"64","author":"Jun JH,","year":"2017","unstructured":"Jun JH,Kim KN,Kim JY,Song SM. The effects of intranasal dexmedetomidine premedication in children: a systematic review and meta-analysis. Can J Anesth. 2017;64:947\u2013961."},{"issue":"5","key":"i1878-7177-71-3-147-b02","series-title":"Anesthesiology","first-page":"885","article-title":"Transmucosal administration of midazolam for premedication of pediatric patients","volume":"78","author":"Karl HW,","year":"1993","unstructured":"Karl HW,Rosenberg JL,Larach MG,Ruffle JM. Transmucosal administration of midazolam for premedication of pediatric patients. Anesthesiology. 1993;78(5):885\u2013891."},{"issue":"8","key":"i1878-7177-71-3-147-b03","series-title":"Eur J Clin Pharmacol","first-page":"825","article-title":"Bioavailability of dexmedetomidine after intranasal administration","volume":"67","author":"Iirola T,","year":"2011","unstructured":"Iirola T,Vilo S,Manner T, et al. Bioavailability of dexmedetomidine after intranasal administration. Eur J Clin Pharmacol. 2011;67(8):825\u2013831."}],"container-title":["Anesthesia Progress"],"original-title":[],"link":[{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/71\/3\/article-p147.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/downloadpdf\/journals\/anpr\/71\/3\/article-p147.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/downloadpdf\/journals\/anpr\/71\/3\/article-p147.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T00:30:18Z","timestamp":1730939418000},"score":1,"resource":{"primary":{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/71\/3\/article-p147.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":3,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.2344\/anpr-23-0057","relation":{},"ISSN":["1878-7177","0003-3006"],"issn-type":[{"type":"electronic","value":"1878-7177"},{"type":"print","value":"0003-3006"}],"subject":[],"published":{"date-parts":[[2024,9]]}}}