{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T11:39:53Z","timestamp":1776857993901,"version":"3.51.2"},"reference-count":9,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"abstract":"Fanconi anemia (FA) is a type of bone marrow failure syndrome based on an autosomal recessive inherited trait with increased predisposition for other cancers. It is extremely rare and is characterized by short stature, polydactyly, and pancytopenia. At present, the only effective treatment for FA is allogeneic hematopoietic stem cell transplantation (SCT). Chemotherapy is necessary prior to allogeneic SCT. Dental treatment is usually performed before chemotherapy to reduce potential infections. We experienced the anesthetic management of a 4-year-old boy diagnosed with FA, who underwent extensive dental extractions before chemotherapy for SCT. In the preoperative examination, the platelet count was decreased to less than 3.0 \u00d7 104<\/jats:sup> cells\/\u03bcL because of chronic pancytopenia. The patient received 20 units of platelet transfusion over 3 days prior to anesthesia. Dental surgery and multiple dental extractions were successfully completed under general anesthesia with sevoflurane, fentanyl, and remifentanil, and chemotherapy started 3 days postoperatively.<\/jats:p>","DOI":"10.2344\/anpr-66-02-06","type":"journal-article","created":{"date-parts":[[2019,12,31]],"date-time":"2019-12-31T15:52:33Z","timestamp":1577807553000},"page":"218-220","source":"Crossref","is-referenced-by-count":2,"title":["Anesthetic Management of a Patient With Fanconi Anemia"],"prefix":"10.2344","volume":"66","author":[{"given":"Saki","family":"Nagano","sequence":"first","affiliation":[{"name":"Department of Dental Anesthesiology, Kyushu University Hospital, Fukuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Tsukamoto","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Kyushu University Hospital, Fukuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Faculty of Dental Science, Kyushu University, Fukuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1191","reference":[{"key":"i0003-3006-66-4-218-b01","series-title":"Blood Rev","first-page":"101","article-title":"Pathophysiology and management of inherited bone marrow failure syndromes","volume":"24","author":"Shimamura \n A,","year":"2010","unstructured":"Shimamura \n A, \n \n \n Alter \n BP, \n \n \n Pathophysiology and management of inherited bone marrow failure syndromes. Blood Rev. 2010;24:101\u2013122."},{"key":"i0003-3006-66-4-218-b02","series-title":"Paediatr Anaesth","first-page":"981","article-title":"Anesthesia and Fanconi anemia: a case report and review of literature","volume":"16","author":"Jacob \n R,","year":"2006","unstructured":"Jacob \n R, \n \n \n Venkatesan \n T. \n \n \n Anesthesia and Fanconi anemia: a case report and review of literature. Paediatr Anaesth. 2006;16:981\u2013985."},{"key":"i0003-3006-66-4-218-b03","series-title":"Braz J Anesthesiol","first-page":"201","article-title":"Anesthesia for a patient with Fanconi anemia for developmental dislocation of the hip: a case report","volume":"64","author":"Dogan \n Z,","year":"2014","unstructured":"Dogan \n Z, \n \n \n Yildiz \n H, \n \n \n Coskuner \n I, \n \n \n Uzel \n M, \n \n \n Garipardic \n M. \n \n \n Anesthesia for a patient with Fanconi anemia for developmental dislocation of the hip: a case report. Braz J Anesthesiol. 2014;64:201\u2013204."},{"key":"i0003-3006-66-4-218-b04","series-title":"Spec Care Dentist","first-page":"71","article-title":"Oral health status in children and adolescents with Fanconi anemia","volume":"36","author":"Lyko \n K,","year":"2016","unstructured":"Lyko \n K, \n \n \n Lemes \n AL, \n \n \n Bonfim \n C, \n \n \n Torres-Pereira \n CC, \n \n \n Amen\u00e1bar \n JM. \n \n \n Oral health status in children and adolescents with Fanconi anemia. Spec Care Dentist. 2016;36:71\u201374."},{"key":"i0003-3006-66-4-218-b05","series-title":"Clin Oral Investig","first-page":"113","article-title":"Dental treatment prior to stem cell transplantation and its influence on the posttransplantation outcome","volume":"7","author":"Melkos \n AB,","year":"2003","unstructured":"Melkos \n AB, \n \n \n Massenkeil \n G, \n \n \n Arnold \n R, \n \n \n Reichart \n PA. \n \n \n Dental treatment prior to stem cell transplantation and its influence on the posttransplantation outcome. Clin Oral Investig. 2003;7:113\u2013115."},{"key":"i0003-3006-66-4-218-b06","series-title":"Brit J Haematol","first-page":"1023","article-title":"Guidelines for the use of platelet transfusion","volume":"122","year":"2003","unstructured":"British Committee for Standards in Hematology, Blood Transfusion Task Force. Guidelines for the use of platelet transfusion. Brit J Haematol. 2003;122:1023."},{"key":"i0003-3006-66-4-218-b07","series-title":"J Anesth","first-page":"268","article-title":"Perioperative management for a patient with chronic pancytopenia: a case of aplastic anemia with persistent neutropenia following preoperative administration of G-CSF","volume":"24","author":"Nakano \n Y,","year":"2010","unstructured":"Nakano \n Y, \n \n \n Okutani \n R. \n \n \n Perioperative management for a patient with chronic pancytopenia: a case of aplastic anemia with persistent neutropenia following preoperative administration of G-CSF. J Anesth. 2010;24:268\u2013271."},{"key":"i0003-3006-66-4-218-b08","series-title":"Paediatr Anaesth","first-page":"343","article-title":"A weight-based formula for tracheal tube size in children","volume":"19","author":"Eipe \n N,","year":"2009","unstructured":"Eipe \n N, \n \n \n Barrowman \n N, \n \n \n Writer \n H, \n \n \n Doherty \n D. \n \n \n A weight-based formula for tracheal tube size in children. Paediatr Anaesth. 2009;19:343\u2013348."},{"key":"i0003-3006-66-4-218-b09","series-title":"J Dent Anesth Pain Med","first-page":"139","article-title":"Anesthetic management of a patient with chromosome 6p duplication: a case report","volume":"17","author":"Morinaga \n S,","year":"2017","unstructured":"Morinaga \n S, \n \n \n Tsukamoto \n M, \n \n \n Yokoyama \n T. \n \n \n Anesthetic management of a patient with chromosome 6p duplication: a case report. J Dent Anesth Pain Med. 2017;17:139\u2013141."}],"container-title":["Anesthesia Progress"],"original-title":[],"link":[{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/66\/4\/article-p218.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/anesthesia-progress\/article-pdf\/66\/4\/218\/2416774\/anpr-66-02-06.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/downloadpdf\/journals\/anpr\/66\/4\/article-p218.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/downloadpdf\/journals\/anpr\/66\/4\/article-p218.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T12:44:14Z","timestamp":1728305054000},"score":1,"resource":{"primary":{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/66\/4\/article-p218.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":9,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.2344\/anpr-66-02-06","relation":{},"ISSN":["0003-3006","1878-7177"],"issn-type":[{"value":"0003-3006","type":"print"},{"value":"1878-7177","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]}}}