{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T03:18:13Z","timestamp":1761621493106},"reference-count":41,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"abstract":"<jats:p>The purpose of this investigation was to compare ibuprofen versus an ibuprofen\/acetaminophen combination for postoperative pain control in a patient model specific to teeth diagnosed with symptomatic irreversible pulpitis and symptomatic apical periodontitis. One hundred and two patients presenting with moderate to severe pain from a maxillary or mandibular posterior tooth diagnosed with symptomatic irreversible pulpitis and symptomatic apical periodontitis were included. Following local anesthetic administration, complete endodontic cleaning and shaping was performed. Patients were randomly assigned to receive identically appearing tablets of ibuprofen 200 mg or a combination of ibuprofen 200 mg\/acetaminophen 216.7 mg with instructions to take 3 tablets every 6 hours as needed for pain. Patients were also given a prescription for an escape medication to take if the study medications did not adequately control their pain. A 4-day diary was used to record pain ratings and medication use. Moderate to severe pain was experienced by 59\u201361% of the patients on postoperative day 1 and 50\u201357% of the patients on day 2, with the pain ratings decreasing over the next 2 days. There were no statistically significant differences between the 2 groups in postoperative pain, percussion pain, or medication use. There was no difference between ibuprofen and the combination of ibuprofen\/acetaminophen in the reduction of postoperative pain following endodontic debridement in patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis.<\/jats:p>","DOI":"10.2344\/anpr-66-03-06","type":"journal-article","created":{"date-parts":[[2019,12,31]],"date-time":"2019-12-31T15:52:33Z","timestamp":1577807553000},"page":"192-201","source":"Crossref","is-referenced-by-count":9,"title":["An Evaluation of Ibuprofen Versus Ibuprofen\/Acetaminophen for Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis"],"prefix":"10.2344","volume":"66","author":[{"given":"Alex","family":"Stamos","sequence":"first","affiliation":[{"name":"Former Graduate Student in Endodontics, The Ohio State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Drum","sequence":"additional","affiliation":[{"name":"Professor and Graduate Program Director, Division of Endodontics, The Ohio State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Al","family":"Reader","sequence":"additional","affiliation":[{"name":"Emeritus Professor, Division of Endodontics, The Ohio State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Nusstein","sequence":"additional","affiliation":[{"name":"Professor and Chair, Division of Endodontics, The Ohio State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Fowler","sequence":"additional","affiliation":[{"name":"Assistant Professor and Predoctoral Director, Division of Endodontics, The Ohio State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mike","family":"Beck","sequence":"additional","affiliation":[{"name":"Emeritus Associate Professor, Division of Biosciences, The Ohio State University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1191","reference":[{"key":"i0003-3006-66-4-192-b01","series-title":"Anesth Analg","first-page":"1170","article-title":"Combining paracetamol (acetaminophen) with nonsteroidal anti-inflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain","volume":"110","author":"Ong \n              CK,","year":"2010","unstructured":"Ong \n              CK, \n            \n            \n              Seymour \n              RA, \n            \n            \n              Lirk \n              P, \n            \n            \n              Merry \n              AF. \n            \n          \n          Combining paracetamol (acetaminophen) with nonsteroidal anti-inflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain. Anesth Analg. 2010;110:1170\u20131179."},{"issue":"12","key":"i0003-3006-66-4-192-b02","series-title":"Cochrane Database Syst Rev.","article-title":"Ibuprofen and\/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth","volume":"12","author":"Bailey \n              E,","year":"2010","unstructured":"Bailey \n              E, \n            \n            \n              Worthington \n              HV, \n            \n            \n              van Wijk \n              A, \n            \n            \n              Yates \n              JM, \n            \n            \n              Coulthard \n              P, \n            \n            \n              Afzal \n              Z. \n            \n          \n          Ibuprofen and\/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth. Cochrane Database Syst Rev.2010;12(12):CD0004624."},{"issue":"6","key":"i0003-3006-66-4-192-b03","series-title":"Cochrane Database Syst Rev.","article-title":"Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain","volume":"24","author":"Derry \n              CJ,","year":"2013","unstructured":"Derry \n              CJ, \n            \n            \n              Derry \n              S, \n            \n            \n              Moore \n              RA. \n            \n          \n          Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain. 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J Am Dent Assoc. 2013;144:898\u2013908."},{"key":"i0003-3006-66-4-192-b06","series-title":"J Endod","first-page":"1146","article-title":"An analysis of current analgesic preferences for endodontic pain management","volume":"32","author":"Mickel \n              AK,","year":"2006","unstructured":"Mickel \n              AK, \n            \n            \n              Wright \n              AP, \n            \n            \n              Chogle \n              S, \n            \n            \n              Jones \n              JJ, \n            \n            \n              Kantorovich \n              I, \n            \n            \n              Curd \n              F. \n            \n          \n          An analysis of current analgesic preferences for endodontic pain management. 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St. Louis, MO: Mosby;2015:117."},{"key":"i0003-3006-66-4-192-b08","series-title":"Int Endod J","first-page":"531","article-title":"The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study","volume":"37","author":"Menhinick \n              KA,","year":"2004","unstructured":"Menhinick \n              KA, \n            \n            \n              Gutmann \n              JL, \n            \n            \n              Regan \n              JD, \n            \n            \n              Taylor \n              SE, \n            \n            \n              Buschang \n              PH. \n            \n          \n          The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study. 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Int J Dent. 2012;2012:310467. doi: 10.1155\/2012\/310467."},{"key":"i0003-3006-66-4-192-b11","series-title":"J Endod","first-page":"7","article-title":"Nonsteroidal anti-inflammatory drugs for managing postoperative endodontic pain in patients who present with preoperative pain: a systematic review and meta-analysis","volume":"43","author":"Smith \n              EA,","year":"2017","unstructured":"Smith \n              EA, \n            \n            \n              Marshall \n              JG, \n            \n            \n              Selph \n              SS, \n            \n            \n              Barker \n              DR, \n            \n            \n              Sedgley \n              CM. \n            \n          \n          Nonsteroidal anti-inflammatory drugs for managing postoperative endodontic pain in patients who present with preoperative pain: a systematic review and meta-analysis. 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Pain. 1984;19:153\u2013161."},{"key":"i0003-3006-66-4-192-b14","series-title":"J Endod","first-page":"593","article-title":"Effect of preoperative ibuprofen\/acetaminophen on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis","volume":"37","author":"Simpson \n              M,","year":"2011","unstructured":"Simpson \n              M, \n            \n            \n              Drum \n              M, \n            \n            \n              Nusstein \n              J, \n            \n            \n              Reader \n              A, \n            \n            \n              Beck \n              M. \n            \n          \n          Effect of preoperative ibuprofen\/acetaminophen on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitis. 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J Am Dent Assoc. 2007;138:1104\u20131112."},{"key":"i0003-3006-66-4-192-b21","series-title":"J Endod","first-page":"487","article-title":"Anesthetic efficacy of the supplemental intraosseous injection of 2% lidocaine with 1:100,000 epinephrine in irreversible pulpitis","volume":"24","author":"Nusstein \n              J,","year":"1998","unstructured":"Nusstein \n              J, \n            \n            \n              Reader \n              A, \n            \n            \n              Nist \n              R, \n            \n            \n              Beck \n              M, \n            \n            \n              Meyers \n              WJ. \n            \n          \n          Anesthetic efficacy of the supplemental intraosseous injection of 2% lidocaine with 1:100,000 epinephrine in irreversible pulpitis. J Endod. 1998;24:487\u2013491."},{"key":"i0003-3006-66-4-192-b22","series-title":"J Endod","first-page":"390","article-title":"Anesthetic success of an inferior alveolar nerve block and supplemental articaine buccal infiltration for molars and premolars in patients with symptomatic irreversible pulpitis","volume":"42","author":"Fowler \n              S,","year":"2016","unstructured":"Fowler \n              S, \n            \n            \n              Drum \n              M, \n            \n            \n              Reader \n              A, \n            \n            \n              Beck \n              M. \n            \n          \n          Anesthetic success of an inferior alveolar nerve block and supplemental articaine buccal infiltration for molars and premolars in patients with symptomatic irreversible pulpitis. J Endod. 2016;42:390\u2013392."},{"key":"i0003-3006-66-4-192-b23","series-title":"J Endod","first-page":"1491","article-title":"A prospective, randomized, single-blind comparative evaluation of anesthetic efficacy of posterior superior alveolar nerve blocks, buccal infiltrations, and buccal plus palatal infiltrations in patients with irreversible pulpitis","volume":"37","author":"Aggarwal \n              V,","year":"2011","unstructured":"Aggarwal \n              V, \n            \n            \n              Singla \n              M, \n            \n            \n              Miglani \n              S, \n            \n            \n              Ansari \n              I, \n            \n            \n              Kohli \n              S. \n            \n          \n          A prospective, randomized, single-blind comparative evaluation of anesthetic efficacy of posterior superior alveolar nerve blocks, buccal infiltrations, and buccal plus palatal infiltrations in patients with irreversible pulpitis. J Endod. 2011;37:1491\u20131494."},{"key":"i0003-3006-66-4-192-b24","series-title":"J Endod","first-page":"279","article-title":"A comparison of the efficacy of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving pulpal anesthesia in maxillary teeth with irreversible pulpitis","volume":"38","author":"Kanaa \n              MD,","year":"2012","unstructured":"Kanaa \n              MD, \n            \n            \n              Whitworth \n              JM, \n            \n            \n              Meechan \n              JG. \n            \n          \n          A comparison of the efficacy of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:80,000 epinephrine in achieving pulpal anesthesia in maxillary teeth with irreversible pulpitis. J Endod. 2012;38:279\u2013282."},{"key":"i0003-3006-66-4-192-b25","series-title":"Int Endod J","first-page":"222","article-title":"Efficacy of single buccal infiltrations for maxillary first molars in patients with irreversible pulpitis: a randomized controlled clinical trial","volume":"47","year":"2014","unstructured":"Atasoy Ulusoy \u00d6\u012a, Ala\u00e7am T. Efficacy of single buccal infiltrations for maxillary first molars in patients with irreversible pulpitis: a randomized controlled clinical trial. Int Endod J. 2014;47:222\u2013227."},{"key":"i0003-3006-66-4-192-b26","series-title":"J Endod","first-page":"1462","article-title":"The effect of maxillary first molar root length on the success rate of buccal infiltration anesthesia","volume":"42","year":"2016","unstructured":"Moradi Askari E, Parirokh M, Nakhaee N, Hosseini HR, Abbott PV. The effect of maxillary first molar root length on the success rate of buccal infiltration anesthesia. J Endod. 2016;42:1462\u20131466."},{"key":"i0003-3006-66-4-192-b27","series-title":"Iran Endod J","first-page":"79","article-title":"V Abbott P, Samani S. Efficacy of articaine and lidocaine for buccal infiltration of first maxillary molars with symptomatic irreversible pulpitis: a randomized double-blinded clinical trial","volume":"11","author":"Hosseini \n              HR,","year":"2016","unstructured":"Hosseini \n              HR, \n            \n            \n              Parirokh \n              M, \n            \n            \n              Nakhaee \n              N, \n            \n          \n          V Abbott P, Samani S. Efficacy of articaine and lidocaine for buccal infiltration of first maxillary molars with symptomatic irreversible pulpitis: a randomized double-blinded clinical trial. Iran Endod J. 2016;11:79\u201384."},{"key":"i0003-3006-66-4-192-b28","series-title":"J Endod","first-page":"1608","article-title":"Efficacy of ibuprofen and ibuprofen\/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis","volume":"37","author":"Wells \n              LK,","year":"2011","unstructured":"Wells \n              LK, \n            \n            \n              Drum \n              M, \n            \n            \n              Nusstein \n              J, \n            \n            \n              Reader \n              A, \n            \n            \n              Beck \n              M. \n            \n          \n          Efficacy of ibuprofen and ibuprofen\/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis. J Endod. 2011;37:1608\u20131612."},{"key":"i0003-3006-66-4-192-b29","series-title":"J Endod","first-page":"378","article-title":"What is the effect of no endodontic debridement on postoperative pain for symptomatic teeth with pulpal necrosis?","volume":"42","author":"Sebastian \n              R,","year":"2016","unstructured":"Sebastian \n              R, \n            \n            \n              Drum \n              M, \n            \n            \n              Reader \n              A, \n            \n            \n              Nusstein \n              J, \n            \n            \n              Fowler \n              S, \n            \n            \n              Beck \n              M. \n            \n          \n          What is the effect of no endodontic debridement on postoperative pain for symptomatic teeth with pulpal necrosis?\n          J Endod. 2016;42:378\u2013382."},{"key":"i0003-3006-66-4-192-b30","series-title":"J Endod","first-page":"796","article-title":"Measurement of mechanical allodynia and local anesthetic efficacy in patients with irreversible pulpitis and acute periradicular periodontitis","volume":"33","author":"Khan \n              AA,","year":"2007","unstructured":"Khan \n              AA, \n            \n            \n              Owatz \n              CB, \n            \n            \n              Schindler \n              WG, \n            \n            \n              Schwartz \n              SA, \n            \n            \n              Keiser \n              K, \n            \n            \n              Hargreaves \n              KM. \n            \n          \n          Measurement of mechanical allodynia and local anesthetic efficacy in patients with irreversible pulpitis and acute periradicular periodontitis. J Endod. 2007;33:796\u2013799."},{"key":"i0003-3006-66-4-192-b31","series-title":"Anesth Prog","first-page":"111","article-title":"A comparison of injection pain and postoperative pain of two intraosseous anesthetic techniques","volume":"50","author":"Gallatin \n              J,","year":"2003","unstructured":"Gallatin \n              J, \n            \n            \n              Nusstein \n              J, \n            \n            \n              Reader \n              A, \n            \n            \n              Beck \n              M, \n            \n            \n              Weaver \n              J. \n            \n          \n          A comparison of injection pain and postoperative pain of two intraosseous anesthetic techniques. Anesth Prog. 2003;50:111\u2013120."},{"key":"i0003-3006-66-4-192-b32","series-title":"J Endod","first-page":"588","article-title":"Acetaminophen: old drug new issues","volume":"41","author":"Aminoshariae \n              A,","year":"2015","unstructured":"Aminoshariae \n              A, \n            \n            \n              Khan \n              A. \n            \n          \n          Acetaminophen: old drug new issues. J Endod. 2015;41:588\u2013593."},{"key":"i0003-3006-66-4-192-b33","series-title":"J Endod","first-page":"345","article-title":"Effectiveness of various medications on postoperative pain following complete instrumentation","volume":"20","author":"Torabinejad \n              M,","year":"1994","unstructured":"Torabinejad \n              M, \n            \n            \n              Cymerman \n              JJ, \n            \n            \n              Frankson \n              M, \n            \n            \n              Lemon \n              RR, \n            \n            \n              Maggio \n              JD, \n            \n            \n              Schilder \n              H. \n            \n          \n          Effectiveness of various medications on postoperative pain following complete instrumentation. J Endod. 1994;20:345\u2013354."},{"key":"i0003-3006-66-4-192-b34","series-title":"J Endod","first-page":"712","article-title":"The effectiveness of prophylactic etodolac on postendodontic pain","volume":"26","author":"Menke \n              E,","year":"2000","unstructured":"Menke \n              E, \n            \n            \n              Jackson \n              C, \n            \n            \n              Bagby \n              M, \n            \n            \n              Tracy \n              T. \n            \n          \n          The effectiveness of prophylactic etodolac on postendodontic pain. 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J Endod. 2003;29:634\u2013637."},{"key":"i0003-3006-66-4-192-b37","series-title":"J Oral Science","first-page":"157","article-title":"Effectiveness of tenoxicam and ibuprofen for pain prevention following endodontic therapy in comparison to placebo: a randomized double-blind clinical trial","volume":"53","author":"Arslan \n              H,","year":"2011","unstructured":"Arslan \n              H, \n            \n            \n              Topcuoglu \n              HS, \n            \n            \n              Aladag \n              H. \n            \n          \n          Effectiveness of tenoxicam and ibuprofen for pain prevention following endodontic therapy in comparison to placebo: a randomized double-blind clinical trial. J Oral Science. 2011;53:157\u2013161."},{"key":"i0003-3006-66-4-192-b38","series-title":"Int Endod J","first-page":"76","article-title":"Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial","volume":"45","author":"Mehrvarzfar \n              P,","year":"2012","unstructured":"Mehrvarzfar \n              P, \n            \n            \n              Abbott \n              PV, \n            \n            \n              Saghir \n              MA, \n            \n            et al. \n          Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial. Int Endod J. 2012;45:76\u201382."},{"key":"i0003-3006-66-4-192-b39","series-title":"J Endod","first-page":"835","article-title":"Double-blind randomized placebo-controlled clinical trial of efficiency of nonsteroidal anti-inflammatory drugs in the control of post-endodontic pain","volume":"42","author":"Elzaki \n              WM,","year":"2016","unstructured":"Elzaki \n              WM, \n            \n            \n              Abubakr \n              NH, \n            \n            \n              Ziada \n              HM, \n            \n            \n              Ibrahim \n              YE. \n            \n          \n          Double-blind randomized placebo-controlled clinical trial of efficiency of nonsteroidal anti-inflammatory drugs in the control of post-endodontic pain. J Endod. 2016;42:835\u2013842."},{"key":"i0003-3006-66-4-192-b40","series-title":"Iran Endod J","first-page":"57","article-title":"Effect of premedication with indomethacin and ibuprofen on postoperative endodontic pain: a clinical trial","volume":"11","author":"Mokhtari \n              F,","year":"2016","unstructured":"Mokhtari \n              F, \n            \n            \n              Yazdi \n              K, \n            \n            \n              Mahabadi \n              AM, \n            \n            \n              Modaresi \n              SJ, \n            \n            \n              Hamzeheil \n              Z. \n            \n          \n          Effect of premedication with indomethacin and ibuprofen on postoperative endodontic pain: a clinical trial. Iran Endod J. 2016;11:57\u201362."},{"key":"i0003-3006-66-4-192-b41","series-title":"J Am Dent Assoc","first-page":"256","article-title":"Benefits and harms associated with analgesic medications used in the management of acute dental pain","volume":"149","author":"Moore \n              PA,","year":"2018","unstructured":"Moore \n              PA, \n            \n            \n              Ziegler \n              KM, \n            \n            \n              Lipman \n              RD, \n            \n            \n              Aminoshariae \n              A, \n            \n            \n              Carrasco-Labra \n              A, \n            \n            \n              Mariotti \n              A. \n            \n          \n          Benefits and harms associated with analgesic medications used in the management of acute dental pain. 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