{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T19:44:57Z","timestamp":1775072697934,"version":"3.50.1"},"reference-count":27,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020]]},"abstract":"Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders of the gastrointestinal tract including ulcerative colitis (UC) and Crohn's disease. Pain management can be challenging in patients with IBD because there are limitations on the use of analgesics. Use of nonsteroidal anti-inflammatory drugs is not recommended in patients with IBD because there is risk of relapse of IBD and an overall increase in disease activity. Opioids, although frequently used for treating severe acute pain, can have additional risks and complications in patients with IBD such as ileus, toxic megacolon, and narcotic bowel syndrome. Furthermore, little information is available in the literature on pain management in these patients undergoing noncolorectal surgery. This report describes 2 patients with UC in whom postoperative pain following oral and maxillofacial surgery was managed by intravenous patient-controlled analgesia with pentazocine. Apart from the development of acute dystonia in 1 case that was likely due to the use of droperidol for prevention of postoperative nausea and vomiting, postoperative pain was well controlled by pentazocine in both patients without any complications or UC exacerbations.<\/jats:p>","DOI":"10.2344\/anpr-67-01-06","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T20:43:28Z","timestamp":1601412208000},"page":"158-163","source":"Crossref","is-referenced-by-count":7,"title":["Postoperative Pain Management in Patients With Ulcerative Colitis"],"prefix":"10.2344","volume":"67","author":[{"given":"Norika","family":"Katagiri","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Kanagawa Dental University Hospital, Yokosuka, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryutaro","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Kanagawa Dental University Hospital, Yokosuka, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Izutsu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Yamagata Prefectural Central Hospital, Yamagata City, Yamagata, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromasa","family":"Kawana","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Implantology, Kanagawa Dental University Hospital, Yokosuka, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigekazu","family":"Sugino","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, Tohoku University Hospital, Sendai, Miyagi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanta","family":"Kido","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Kanagawa Dental University Hospital, Yokosuka, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1191","reference":[{"key":"i0003-3006-67-3-158-b01","series-title":"Scand J Gastroenterol Suppl.","first-page":"63","article-title":"IBD and genetics: new developments","volume":"38","author":"Oostenbrug","year":"2003","unstructured":"Oostenbrug\n LE,\n \n \n van Dullemen\n HM,\n \n \n te Meerman\n GJ,\n \n \n Jansen\n PL.\n \n \n IBD and genetics: new developments.\n\t\t\t\t\tScand J Gastroenterol Suppl.2003;38:63\u201368."},{"key":"i0003-3006-67-3-158-b02","series-title":"Pain Pract","first-page":"132","article-title":"Effect of a preoperative gabapentin on postoperative analgesia in patients with inflammatory bowel disease following major bowel surgery: a randomized, placebo-controlled trial","volume":"14","author":"Siddiqui","year":"2014","unstructured":"Siddiqui\n NT,\n \n \n Fischer\n H,\n \n \n Guerina\n L,\n \n \n Friedman\n Z.\n \n \n Effect of a preoperative gabapentin on postoperative 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al.\n\t\t\t\t\t\n Healing impairment effect of cyclooxygenase inhibitors on dextran sulfate sodium-induced colitis in rats.\n\t\t\t\t\tDigestion.\n\t\t\t\t\t2006;74:91\u2013100."},{"key":"i0003-3006-67-3-158-b17","series-title":"Clin Gastroenterol Hepatol","first-page":"196","article-title":"Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease","volume":"4","author":"Takeuchi","year":"2006","unstructured":"Takeuchi\n K,\n \n \n Smale\n S,\n \n \n Premchand\n P,\n \n et al.\n\t\t\t\t\t\n Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease.\n\t\t\t\t\tClin Gastroenterol Hepatol.\n\t\t\t\t\t2006;4:196\u2013202."},{"key":"i0003-3006-67-3-158-b18","series-title":"Br J Anaesth","first-page":"199","article-title":"Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review","volume":"88","author":"Hyllested","year":"2002","unstructured":"Hyllested\n M,\n \n \n Jones\n S,\n \n \n Pedersen\n JL,\n \n \n Kehlet\n H.\n \n \n Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review.\n\t\t\t\t\tBr J Anaesth.\n\t\t\t\t\t2002;88:199\u2013214."},{"key":"i0003-3006-67-3-158-b19","series-title":"Gastroenterol Hepatol (N Y)","first-page":"592","article-title":"Managing pain in inflammatory bowel disease","volume":"7","author":"Docherty","year":"2011","unstructured":"Docherty\n MJ,\n \n \n Jones\n RC\n 3rd,\n \n \n Wallace\n MS.\n \n \n Managing pain in inflammatory bowel disease.\n\t\t\t\t\tGastroenterol Hepatol (N Y).\n\t\t\t\t\t2011;7:592\u2013601."},{"key":"i0003-3006-67-3-158-b20","series-title":"Inflamm Bowel Dis","first-page":"869","article-title":"Narcotic use for inflammatory bowel disease and risk factors during hospitalization","volume":"18","author":"Long","year":"2012","unstructured":"Long\n MD,\n \n \n Barnes\n EL,\n \n \n Herfarth\n HH,\n \n \n Drossman\n DA.\n \n \n Narcotic use for inflammatory bowel disease and risk factors during hospitalization.\n\t\t\t\t\tInflamm Bowel Dis.\n\t\t\t\t\t2012;18:869\u2013876."},{"key":"i0003-3006-67-3-158-b21","series-title":"Adv Ther","first-page":"714","article-title":"The role of opioid receptor antagonists in the treatment of opioid-induced constipation: a review","volume":"27","author":"Leppert","year":"2010","unstructured":"Leppert\n W.\n \n \n The role of opioid receptor antagonists in the treatment of opioid-induced constipation: a review.\n\t\t\t\t\tAdv Ther.\n\t\t\t\t\t2010;27:714\u2013730."},{"issue":"(suppl 2)","key":"i0003-3006-67-3-158-b22","series-title":"Neurogastroenterol Motil","first-page":"3","article-title":"The opioid system in the gastrointestinal tract","volume":"16","author":"Sternini","year":"2004","unstructured":"Sternini\n 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Pharmacol","first-page":"63","article-title":"Effects of mu- and kappa-opioid receptors on postoperative ileus in rats","volume":"339","author":"De Winter","year":"1997","unstructured":"De Winter\n BY,\n \n \n Boeckxstaens\n GE,\n \n \n De Man\n JG,\n \n \n Moreels\n TG,\n \n \n Herman\n AG,\n \n \n Pelckmans\n PA.\n \n \n Effects of mu- and kappa-opioid receptors on postoperative ileus in rats.\n\t\t\t\t\tEur J Pharmacol1997;339:63\u201367."},{"key":"i0003-3006-67-3-158-b26","series-title":"Cureus","first-page":"e948","article-title":"Analgesic effect of preoperative pentazocine for laparoscopic cholecystectomy","volume":"8","author":"Wang","year":"2016","unstructured":"Wang\n N,\n \n \n Wang\n L,\n \n \n Gao\n Y,\n \n \n Zhou\n H,\n \n \n Wang\n J.\n \n \n Analgesic effect of preoperative pentazocine for laparoscopic cholecystectomy.\n\t\t\t\t\tCureus.\n\t\t\t\t\t2016;8:e948."},{"key":"i0003-3006-67-3-158-b27","series-title":"J Korean Med Sci","first-page":"715","article-title":"Acute dystonia by droperidol during intravenous patient-controlled analgesia in young patients","volume":"17","author":"Park","year":"2002","unstructured":"Park\n CK,\n \n \n Choi\n HY,\n \n \n Oh\n IY,\n \n \n Kim\n MS.\n \n \n Acute dystonia by droperidol during intravenous patient-controlled analgesia in young patients.\n\t\t\t\t\tJ Korean Med Sci.\n\t\t\t\t\t2002;17:715\u2013717."}],"container-title":["Anesthesia 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