{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:43:18Z","timestamp":1790707398271,"version":"4.1.0"},"reference-count":22,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective:<\/jats:title>\n                  <jats:p>The incidence of postoperative nausea and vomiting (PONV) after general anesthesia with total intravenous anesthesia (TIVA) was reported to be significantly lower than with volatile inhalational agents (13.3% vs 25%). However, no investigation of PONV risk factors associated with TIVA has ever been reported. This cross-sectional retrospective study aimed to investigate whether known risk factors influenced PONV in intubated general anesthetics utilizing TIVA for dental or oral and maxillofacial surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods:<\/jats:title>\n                  <jats:p>Subjects were 761 patients who underwent dental or oral and maxillofacial surgery under TIVA with propofol, fentanyl, and remifentanil. Univariate and multivariable logistic regression analyses were performed using PONV (within 24 hours) as the dependent variable and previously reported risk factors as independent variables.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results:<\/jats:title>\n                  <jats:p>Age (odds ratio [OR]: 1.020 per year decrease; 95% confidence interval [CI]: 1.0002\u20131.0418; P = .047) and female sex (OR: 2.73; 95% CI: 1.60\u20134.84; P &amp;lt; .001) were positively associated with PONV. Sagittal split ramus osteotomy (SSRO) (OR: 2.28; 95% CI: 1.21\u20134.33; P = .011) and bimaxillary osteotomy (OR: 5.69; 95% CI: 2.09\u201315.99; P &amp;lt; .001) were more likely to be associated with PONV than operations that were neither bimaxillary osteotomy nor SSRO. Late PONV (2\u201324 hours) had an \u223c2.7 times higher incidence than early PONV (0\u20132 hours).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion:<\/jats:title>\n                  <jats:p>These findings suggest further PONV countermeasures, aside from TIVA with propofol and prophylactic antiemetics for orthognathic surgeries especially bimaxillary osteotomy, are needed.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2344\/anpr-68-03-12","type":"journal-article","created":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T12:10:59Z","timestamp":1649074259000},"page":"18-23","source":"Crossref","is-referenced-by-count":13,"title":["Cross-sectional Study of PONV Risk Factors for Oral Surgery After Intubated General Anesthesia With Total Intravenous Anesthesia"],"prefix":"10.2344","volume":"69","author":[{"given":"Emi","family":"Ishikawa","sequence":"first","affiliation":[{"name":"Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rie","family":"Iwamoto","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Hojo","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahito","family":"Teshirogi","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiji","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makiko","family":"Shibuya","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukifumi","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Fujisawa","sequence":"additional","affiliation":[{"name":"Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1191","published-online":{"date-parts":[[2022,4,4]]},"reference":[{"key":"2022040416094031500_i0003-3006-69-1-18-b01","doi-asserted-by":"crossref","unstructured":"Laskin\n              DM,\n            \n            \n              Carrico\n              CK,\n            \n            \n              Wood\n              J.\n            \n          \n          Predicting postoperative nausea and vomiting in patients undergoing oral and maxillofacial surgery.\n\t\t\t\t\tInt J Oral Maxillofac 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Its etiology, treatment, and prevention.\n\t\t\t\t\tAnesthesiology.\n\t\t\t\t\t1992;\n\t\t\t\t\t77:\n\t\t\t\t\t162\u2013\n\t\t\t\t\t184.","DOI":"10.1097\/00000542-199207000-00023"},{"key":"2022040416094031500_i0003-3006-69-1-18-b14","doi-asserted-by":"crossref","unstructured":"Lerman\n              J.\n            \n          \n          Surgical and patient factors involved in postoperative nausea and vomiting.\n\t\t\t\t\tBr J Anaesth.\n\t\t\t\t\t1992;\n\t\t\t\t\t69(7 suppl 1):\n\t\t\t\t\t24S\u2013\n\t\t\t\t\t32S.","DOI":"10.1093\/bja\/69.supplement_1.24S"},{"key":"2022040416094031500_i0003-3006-69-1-18-b15","doi-asserted-by":"crossref","unstructured":"Brookes\n              CD,\n            \n            \n              Berry\n              J,\n            \n            \n              Rich\n              J,\n            \n            et al.\n\t\t\t\t\t\n          Multimodal protocol reduces postoperative nausea and vomiting in patients undergoing Le Fort I osteotomy.\n\t\t\t\t\tJ Oral Maxillofac Surg.\n\t\t\t\t\t2015;\n\t\t\t\t\t73:\n\t\t\t\t\t324\u2013\n\t\t\t\t\t332.","DOI":"10.1016\/j.joms.2014.08.007"},{"key":"2022040416094031500_i0003-3006-69-1-18-b16","doi-asserted-by":"crossref","unstructured":"Habib\n              AS,\n            \n            \n              White\n              WD,\n            \n            \n              Eubanks\n              S,\n            \n            \n              Pappas\n              TN,\n            \n            \n              Gan\n              TJ.\n            \n          \n          A randomized comparison of a multimodal management strategy versus combination antiemetics for the prevention of postoperative nausea and vomiting.\n\t\t\t\t\tAnesth Analg.\n\t\t\t\t\t2004;\n\t\t\t\t\t99:\n\t\t\t\t\t77\u2013\n\t\t\t\t\t81.","DOI":"10.1213\/01.ANE.0000120161.30788.04"},{"key":"2022040416094031500_i0003-3006-69-1-18-b17","doi-asserted-by":"crossref","unstructured":"Andrews\n              PL.\n            \n          \n          Physiology of nausea and vomiting.\n\t\t\t\t\tBr J Anaesth.\n\t\t\t\t\t1992;\n\t\t\t\t\t69(7 suppl 1):\n\t\t\t\t\t2S\u2013\n\t\t\t\t\t19S.","DOI":"10.1093\/bja\/69.supplement_1.2S"},{"key":"2022040416094031500_i0003-3006-69-1-18-b18","doi-asserted-by":"crossref","unstructured":"Borgeat\n              A,\n            \n            \n              Wilder-Smith\n              OH,\n            \n            \n              Suter\n              PM.\n            \n          \n          The nonhypnotic therapeutic applications of propofol.\n\t\t\t\t\tAnesthesiology.\n\t\t\t\t\t1994;\n\t\t\t\t\t80:\n\t\t\t\t\t642\u2013\n\t\t\t\t\t656.","DOI":"10.1097\/00000542-199403000-00022"},{"key":"2022040416094031500_i0003-3006-69-1-18-b19","doi-asserted-by":"crossref","unstructured":"Apfel\n              CC,\n            \n            \n              Korttila\n              K,\n            \n            \n              Abdalla\n              M,\n            \n            et al;\n          \n          IMPACT Investigators. 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