{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T13:21:05Z","timestamp":1776777665148,"version":"3.51.2"},"reference-count":15,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,1]]},"abstract":"<jats:p>This is a case report of an 81-year-old woman who underwent tracheostomy, bilateral cervical dissection, partial tongue resection, radial forearm free flap reconstruction, and split-thickness skin grafting under general anesthesia. After successful surgery, she was moderately sedated postoperatively with intravenous dexmedetomidine (DEX) and fentanyl. The fentanyl was discontinued 5 hours postoperatively. Eight hours after the operation, an atrioventricular junctional rhythm, a 2-mm elevation of the ST segment, and biphasic T waves were detected in lead II that lasted approximately 3 minutes. Hypotension and bradycardia were observed simultaneously with the abnormal electrocardiogram. The next day, a cardiologist examined the patient and suggested that coronary spasm had occurred based on those findings. The transient coronary spasm was likely caused by a combination of various factors including surgical stress and altered autonomic function. However, it is possible that stimulation of \u03b1-2 adrenergic receptors induced by DEX may also be linked to the coronary vasospasm that occurred.<\/jats:p>","DOI":"10.2344\/anpr-69-01-02","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T15:51:42Z","timestamp":1665589902000},"page":"20-24","source":"Crossref","is-referenced-by-count":5,"title":["Coronary Spasm During Postoperative Sedation With Dexmedetomidine"],"prefix":"10.2344","volume":"69","author":[{"given":"Yu","family":"Sato","sequence":"first","affiliation":[{"name":"Dental Anesthesiology and Orofacial Pain Management, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoka","family":"Matsumura","sequence":"additional","affiliation":[{"name":"Dental Anesthesiology and Orofacial Pain Management, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yushi","family":"Abe","sequence":"additional","affiliation":[{"name":"Dental Anesthesiology and Orofacial Pain Management, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chihiro","family":"Kutsumizu","sequence":"additional","affiliation":[{"name":"Dental Anesthesiology and Orofacial Pain Management, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Maeda","sequence":"additional","affiliation":[{"name":"Dental Anesthesiology and Orofacial Pain Management, Tokyo Medical and Dental University, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1191","published-online":{"date-parts":[[2022,10,6]]},"reference":[{"key":"2022101215510028000_i1878-7177-69-3-20-b01","doi-asserted-by":"crossref","unstructured":"Correa-Sales\n              C,\n       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