{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T08:02:54Z","timestamp":1771488174134,"version":"3.50.1"},"reference-count":15,"publisher":"American Dental Society of Anesthesiology (ADSA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,1]]},"abstract":"<jats:p>Two case reports present the use of vasopressin for treating refractory hypotension associated with continued angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) therapy prior to general anesthesia for oral surgery. Both patients were treated in an ambulatory dental surgery clinic and took either their ACEI or ARB medication for hypertension within 24 hours prior to undergoing an intubated general anesthetic. Persistent profound hypotension was encountered intraoperatively that was refractory to treatment with traditional methods. However, the ACEI- or ARB-induced refractory hypotension was successfully managed with the administration of vasopressin.<\/jats:p>","DOI":"10.2344\/anpr-69-02-06","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T15:52:44Z","timestamp":1665589964000},"page":"30-35","source":"Crossref","is-referenced-by-count":3,"title":["ACE-Inhibitor or ARB-Induced Refractory Hypotension Treated With Vasopressin in Patients Undergoing General Anesthesia for Dentistry: Two Case Reports"],"prefix":"10.2344","volume":"69","author":[{"given":"Caitlin M.","family":"Waters","sequence":"first","affiliation":[{"name":"*Department of Dental Anesthesiology, University of Pittsburgh School of Dental Medicine, Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen","family":"Pelczar","sequence":"additional","affiliation":[{"name":"*Department of Dental Anesthesiology, University of Pittsburgh School of Dental Medicine, Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward C.","family":"Adlesic","sequence":"additional","affiliation":[{"name":"*Department of Dental Anesthesiology, University of Pittsburgh School of Dental Medicine, Pittsburgh, Pennsylvania"},{"name":"\u2020Department of Oral and Maxillofacial Surgery, University of Pittsburgh School of Dental Medicine, Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"*Department of Dental Anesthesiology, University of Pittsburgh School of Dental Medicine, Pittsburgh, Pennsylvania"},{"name":"\u2020Department of Oral and Maxillofacial Surgery, University of Pittsburgh School of Dental Medicine, Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Joseph A.","family":"Giovannitti","sequence":"additional","affiliation":[{"name":"*Department of Dental Anesthesiology, University of Pittsburgh School of Dental Medicine, Pittsburgh, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1191","published-online":{"date-parts":[[2022,10,6]]},"reference":[{"key":"2022101215510131100_i1878-7177-69-3-30-b01","doi-asserted-by":"crossref","unstructured":"Marik\n              PE,\n            \n            \n              Varon\n              J.\n            \n          \n          Perioperative hypertension: a review of current and emerging therapeutic agents.\n\t\t\t\t\tJ Clin Anesth.\n\t\t\t\t\t2009;21:\n\t\t\t\t\t220\u2013229.","DOI":"10.1016\/j.jclinane.2008.09.003"},{"key":"2022101215510131100_i1878-7177-69-3-30-b02","doi-asserted-by":"crossref","unstructured":"Varon\n              J,\n            \n            \n              Marik\n              PE.\n            \n          \n          Perioperative hypertension management.\n\t\t\t\t\tVasc Health Risk Manag.\n\t\t\t\t\t2008;4:\n\t\t\t\t\t615\u2013627.","DOI":"10.2147\/VHRM.S2471"},{"key":"2022101215510131100_i1878-7177-69-3-30-b03","doi-asserted-by":"crossref","unstructured":"Nabbi\n              R,\n            \n            \n              Woehlck\n              HJ,\n            \n            \n              Riess\n              ML.\n            \n          \n          Refractory hypotension during general anesthesia despite preoperative discontinuation of an angiotensin receptor blocker.\n\t\t\t\t\tF1000Res.\n\t\t\t\t\t2013;2:\n\t\t\t\t\t12.","DOI":"10.12688\/f1000research.2-12.v1"},{"key":"2022101215510131100_i1878-7177-69-3-30-b04","unstructured":"Thoma\n              A.\n            \n          \n          Pathophysiology and management of angiotensin-converting enzyme inhibitor-associated refractory hypotension during the perioperative period.\n\t\t\t\t\tAANA J.\n\t\t\t\t\t2013;81(2):133\u2013140."},{"key":"2022101215510131100_i1878-7177-69-3-30-b05","doi-asserted-by":"crossref","unstructured":"Walsh\n              M,\n            \n            \n              Devereaux\n              PJ,\n            \n            \n              Garg\n              AX,\n            \n            et al.\n          \n          Relationship between intraoperative mean arterial pressure and clinical outcomes after noncardiac surgery: toward an empirical definition of hypotension.\n\t\t\t\t\tAnesthesiology.\n\t\t\t\t\t2013;119:\n\t\t\t\t\t507\u2013515.","DOI":"10.1097\/ALN.0b013e3182a10e26"},{"key":"2022101215510131100_i1878-7177-69-3-30-b06","doi-asserted-by":"crossref","unstructured":"Salmasi\n              V,\n            \n            \n              Maheshwari\n              K,\n            \n            \n              Yang\n              D,\n            \n            et al.\n          \n          Relationship between intraoperative hypotension, defined by either reduction from baseline or absolute thresholds, and acute kidney and myocardial injury after noncardiac surgery: a retrospective cohort analysis.\n\t\t\t\t\tAnesthesiology.\n\t\t\t\t\t2017;126:\n\t\t\t\t\t47\u201365.","DOI":"10.1097\/ALN.0000000000001432"},{"key":"2022101215510131100_i1878-7177-69-3-30-b07","doi-asserted-by":"crossref","unstructured":"Wheeler\n              AD,\n            \n            \n              Turchiano\n              J,\n            \n            \n              Tobias\n              JD.\n            \n          \n          A case of refractory intraoperative hypotension treated with vasopressin infusion.\n\t\t\t\t\tJ Clin Anesth.\n\t\t\t\t\t2008;20(2):139\u2013142.","DOI":"10.1016\/j.jclinane.2007.06.023"},{"key":"2022101215510131100_i1878-7177-69-3-30-b08","doi-asserted-by":"crossref","unstructured":"Fleisher\n              LA,\n            \n            \n              Fleischmann\n              KE,\n            \n            \n              Auerbach\n              AD,\n            \n            et al.\n          \n          2014 ACC\/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines.\n\t\t\t\t\tCirculation.\n\t\t\t\t\t2014;130:\n\t\t\t\t\te278\u2013e333.","DOI":"10.1161\/CIR.0000000000000104"},{"key":"2022101215510131100_i1878-7177-69-3-30-b09","doi-asserted-by":"crossref","unstructured":"Smith\n              I,\n            \n            \n              Jackson\n              I.\n            \n          \n          Beta-blockers, calcium channel blockers, angiotensin converting enzyme inhibitors and angiotensin receptor blockers: should they be stopped or not before ambulatory anesthesia?\n          \n            Curr Opin Anesthesiol\n          .\n\t\t\t\t\t2010;23(6):687\u2013690.","DOI":"10.1097\/ACO.0b013e32833eeb19"},{"key":"2022101215510131100_i1878-7177-69-3-30-b10","doi-asserted-by":"crossref","unstructured":"Hollmann\n              C,\n            \n            \n              Fernandes\n              N,\n            \n            \n              Biccard\n              B.\n            \n          \n          A systematic review of outcomes associated with withholding or continuing angiotensin-converting enzyme inhibitors and angiotensin receptor blockers before noncardiac surgery.\n\t\t\t\t\tInternat Anesth Res Soc.\n\t\t\t\t\t2018;127:\n\t\t\t\t\t678\u2013687.","DOI":"10.1213\/ANE.0000000000002837"},{"key":"2022101215510131100_i1878-7177-69-3-30-b11","doi-asserted-by":"crossref","unstructured":"Meersschaert\n              K,\n            \n            \n              Brun\n              L,\n            \n            \n              Gourdin\n              M,\n            \n            et al.\n          \n          Terlipressin-ephedrine versus ephedrine to treat hypotension at the induction of anesthesia in patients chronically treated with angiotensin converting-enzyme inhibitors: a prospective, randomized, double-blinded, crossover study.\n\t\t\t\t\tAnesth Analg.\n\t\t\t\t\t2002;94(4):835\u2013840.","DOI":"10.1097\/00000539-200204000-00011"},{"key":"2022101215510131100_i1878-7177-69-3-30-b12","doi-asserted-by":"crossref","unstructured":"Kheterpal\n              S,\n            \n            \n              Khodaparast\n              O,\n            \n            \n              Shanks\n              A,\n            \n            et al.\n          \n          Chronic angiotensin-converting enzyme inhibitor or angiotensin receptor blocker therapy combined with diuretic therapy is associated with increased episodes of hypotension in noncardiac surgery.\n\t\t\t\t\tJ Cardiothorac Vasc Anesth.\n\t\t\t\t\t2008;22:\n\t\t\t\t\t180\u2013186.","DOI":"10.1053\/j.jvca.2007.12.020"},{"key":"2022101215510131100_i1878-7177-69-3-30-b13","doi-asserted-by":"crossref","unstructured":"Lange\n              M,\n            \n            \n              Hugo\n              VA,\n            \n            \n              Westphal\n              M,\n            \n            \n              Morelli\n              A.\n            \n          \n          Role of vasopressinergic V1 receptor agonists in the treatment of perioperative catecholamine-refractory arterial hypotension. Best Pract Res Clin Anaesthesiol.\n          2008;\n\t\t\t\t\t22(2);369\u2013381.","DOI":"10.1016\/j.bpa.2008.02.010"},{"key":"2022101215510131100_i1878-7177-69-3-30-b14","doi-asserted-by":"crossref","unstructured":"Treschan\n              TA,\n            \n            \n              Peters\n              J.\n            \n          \n          The vasopressin system: physiology and clinical strategies.\n\t\t\t\t\tAnesthesiology.\n\t\t\t\t\t2006;105(3):599\u2013612,\n\t\t\t\t\t639\u2013640.","DOI":"10.1097\/00000542-200609000-00026"},{"key":"2022101215510131100_i1878-7177-69-3-30-b15","doi-asserted-by":"crossref","unstructured":"Liu\n              H,\n            \n            \n              Yu\n              L,\n            \n            \n              Yank\n              L,\n            \n            \n              Green\n              M.\n            \n          \n          Vasoplegic syndrome: an update on perioperative considerations.\n\t\t\t\t\tJ Clin Anesth.\n\t\t\t\t\t2017;40:\n\t\t\t\t\t63\u201371.","DOI":"10.1016\/j.jclinane.2017.04.017"}],"container-title":["Anesthesia Progress"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/meridian.allenpress.com\/anesthesia-progress\/article-pdf\/69\/3\/30\/3128856\/i1878-7177-69-3-30.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/meridian.allenpress.com\/anesthesia-progress\/article-pdf\/69\/3\/30\/3128856\/i1878-7177-69-3-30.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T19:50:51Z","timestamp":1705607451000},"score":1,"resource":{"primary":{"URL":"https:\/\/anesthesiaprogress.kglmeridian.com\/view\/journals\/anpr\/69\/3\/article-p30.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,1]]},"references-count":15,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,10,6]]},"published-print":{"date-parts":[[2022,9,1]]}},"URL":"https:\/\/doi.org\/10.2344\/anpr-69-02-06","relation":{},"ISSN":["1878-7177","0003-3006"],"issn-type":[{"value":"1878-7177","type":"electronic"},{"value":"0003-3006","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9,1]]}}}